Carbon-X vs occamy-1.0

Carbon-X

A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

occamy-1.0

A Qwen3.6-35B-A3B fine-tuned for long agent work with tools, files and code, under plain Apache 2.0, and Accio's 4-bit builds run in about 23 GB. The main gaps are no safety results, agent guidance or security contact, and every benchmark figure is Accio's own.

Carbon-X

1. Quickest start is llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades

occamy-1.0

1. Serve with --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder on vLLM 0.19.0 or SGLang 0.5.10 and later
2. BF16 is 70.2 GB, so on a 128 GB machine run it without the card's 8-way tensor parallelism
3. Keep the whole assistant message, reasoning and tool calls included, in later turns, as the card says
4. Sampling per the card is temperature 1.0, top_p 0.95, top_k 20 and presence_penalty 1.5
5. With the GGUFs, NFC-normalise input text and read TOKENIZER.md, since the files store qwen2 pre-tokenizer metadata
6. The base's MTP layer isn't in this checkpoint, Accio-Lab/occamy-1.0-MTP is an experimental separate head