Apertus v1.5 8B vs Carbon-X

Apertus v1.5 8B

A fully open 8B cousin, training data included, for multilingual chat and tool calls with images and audio in. It needs about 22 GB in BF16 and Swiss AI's own vLLM or Transformers fork, since no released runtime supports it. The main risks are a gated download with a policy to pass on and tools that fail with thinking on.

Carbon-X

A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

Apertus v1.5 8B

1. Accept the terms on the card and set HF_TOKEN before downloading
2. Use Swiss AI's Docker image ghcr.io/swiss-ai/vllm_apertus_1.5_release, since stock vLLM and Transformers don't load Apertus1p5ForConditionalGeneration yet
3. Serve with --chat-template-content-format string --enable-auto-tool-choice --tool-call-parser apertus for tools, and leave thinking off when you need tools
4. For thinking, set --reasoning-parser apertus and --default-chat-template-kwargs.enable_thinking true, and budget max tokens generously
5. Audio is resampled to 24 kHz and costs 40 tokens a second, and video must be passed as frames
6. Don't cast the loaded model with .half(), the image and audio tokenizers must stay in F32
7. If you redistribute the weights, the policy says you must pass it on and get the recipient's express assent

Carbon-X

1. Quickest start is llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades