Apodex-1.1-mini vs Carbon-X

Apodex-1.1-mini

An agent cousin fine-tuned from Qwen3.5-35B-A3B for long tasks with files, code and tools, with parallel tool calling and about 3B active parameters. It needs 32 GB for Apodex's GGUF, NVFP4 or GPTQ-Int4 builds or about 86 GB in BF16, and Apodex's API serves it too. The main risks are no safety results and no replies from the publisher.

Carbon-X

A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

Apodex-1.1-mini

1. Serve it with vllm serve apodex/Apodex-1.1-mini --enable-auto-tool-choice --tool-call-parser qwen3_coder --reasoning-parser qwen3, or the same parsers in SGLang, so tool calls and reasoning come back parsed
2. For llama.cpp, llama-server -hf apodex/Apodex-1.1-mini-GGUF:Q4_K_M --jinja --reasoning-format deepseek, and the card passes the repository's chat_template.jinja with --chat-template-file
3. Pass tools through the API's tools parameter rather than in the system prompt, as the card asks
4. The card recommends temperature 1.0, top_p 0.95, repetition_penalty 1.05 and max_tokens up to 32,768
5. Send your own system prompt, or set identity_mode, since the template otherwise adds an Apodex identity block
6. The template keeps all earlier reasoning in the context unless preserve_thinking is false, which grows long agent sessions
7. Thinking is on by default, send chat_template_kwargs with enable_thinking false for short tasks, a switch the card doesn't mention
8. The card's Python example has a broken line where it runs the tool (available_toolsname), so fix it to available_tools[name](**args) before running
9. Validate JSON output yourself, since structured output isn't documented

Carbon-X

1. Quickest start is llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades