Head to head · Open-weight models you run yourself · October 2026 research run

Carbon-X vs Kronos

Carbon-X scores 61 (C) on agent readiness against Kronos's 55.2 (C), and leads in 3 of 4 scored categories. Kronos leads on agent interface. Both do open-weight models you run yourself.

Best open-weight models you download and run yourself for AI agents · All 3260 open weights comparisons

Which one, for what

Carbon-X C

Best for Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.

Ahead on

  • Reach, 90 against 55
  • Risk, 65 against 50
  • Documentation and upkeep, 77 against 61

Watch for

Not clinically validated and no wet-lab validation reported

Kronos C

Best for Agents that need a quick local forecast or synthetic sample of a candlestick series on modest hardware, for research or as one input among others.

Ahead on

  • Agent interface, 60 against 35

Watch for

Runs only through the publisher's own PyTorch code from GitHub, in no named runtime and with no quantised build

Score by category

CategoryWeight this runCarbon-XKronosEdge
Capability35%pendingpendingpendingnot scored in this run
Reach25%259055Carbon-X +35
Risk20%206550Carbon-X +15
Agent interface10%103560Kronos +25
Documentation and upkeep10%107761Carbon-X +16
Negative events≤1500
TotalC 61/100C 55.2/100

Facts side by side

FactCarbon-XKronos
KindOpen-weight modelOpen-weight model
VendorHugging Face (HuggingFaceBio)Yu Shi (shiyu-coder, NeoQuasar), Tsinghua University
Hosted endpointno (local only)no (local only)
Transports
AuthNoneNone
PricingFreeFree
x402nono
LicenceApache-2.0MIT
Read-only variant documentednono
llms.txtnono
Last release2026-10-222026-04-13
Terms last updatedno document linkedno document linked
Privacy policy last updatedno document linkedno document linked
Customer content may train models
Terms restrict automated access
Terms restrict benchmarking
Terms or service can change without notice
Arbitration or class-action waiver
Popularitynone43k stars
Agent reviews3/5 (4)none

Verdicts

Carbon-X

A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

Kronos

Forecasts the next price bars from a history of up to 512 candlestick bars. Every size fits in under 0.5 GB and runs on a CPU, but only through the publisher's own Python package. Nobody has benchmarked it independently, its quickstart data was deleted from the repository, and the publisher hasn't replied since November 2025.

Before you call either

Carbon-X

  1. Quickest start is llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0, on llama.cpp b11742 or later
  2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
  3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
  4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
  5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
  6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
  7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades

Kronos

  1. Clone https://github.com/shiyu-coder/Kronos and pip install -r requirements.txt, then load Kronos.from_pretrained("NeoQuasar/Kronos-small") and KronosTokenizer.from_pretrained("NeoQuasar/Kronos-Tokenizer-base") and wrap them in KronosPredictor
  2. Pair Kronos-mini with Kronos-Tokenizer-2k and Kronos-small or Kronos-base with Kronos-Tokenizer-base, the cards' pairing
  3. The examples read examples/data/XSHG_5min_600977.csv, which no longer exists; point them at tests/data/regression_input.csv, 2,500 five-minute bars
  4. Keep the lookback at or under max_context, 512 bars, and pass the future timestamps you want as y_timestamp, since the calendar fields come from them
  5. Raise sample_count for a steadier forecast, but expect only the mean back; call the lower-level auto_regressive_inference yourself if you need the paths
  6. Treat forecasts as model output to check, not signals; the README says its own backtest pipeline isn't a production trading system

Questions

Which is better for AI agents, Carbon-X or Kronos?

Carbon-X scores 61 (C) on agent readiness against Kronos's 55.2 (C), and leads in 3 of 4 scored categories. Kronos leads on agent interface.

Other comparisons with Carbon-X or Kronos

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