# Apodex-1.1-mini vs Carbon-X

> Apodex-1.1-mini and Carbon-X score within a point of each other for open-weight models you run yourself, 61 and 61 out of 100. Prices, MCP, x402, uptime and agent notes side by side.

- Canonical: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x
- Markdown: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md (~6,150 tokens)
- Slim: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.min.md (~430 tokens, same facts, less prose, for token-sensitive contexts)
- JSON: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json (this page as data, same URL with Accept: application/json)
- Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt)
- API: https://www.anchorterminal.com/api/v1/index.json
- MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key)
- Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data)
- Updated: 2026-10-23

Apodex-1.1-mini and Carbon-X score within a point of each other on agent readiness, 61 (C) and 61 (C). Carbon-X leads on reach and documentation and upkeep. Both do open-weight models you run yourself.

- Apodex-1.1-mini: grade C, 61/100, rank #37 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/apodex-1-1-mini.md · JSON https://www.anchorterminal.com/api/v1/tools/apodex-1-1-mini.json
- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json
- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md
- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md

## Which one, for what

### Apodex-1.1-mini (C)

Good for: Long-running agent tasks with tools on a 32 GB GPU or Mac, or through Apodex's API, under a plain licence

Ahead on:
- Agent interface, 85 against 35

Watch for: No safety results, and agent guidance only from the harness

### Carbon-X (C)

Good for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.

Ahead on:
- Reach, 90 against 85
- Documentation and upkeep, 77 against 38

Watch for: Not clinically validated and no wet-lab validation reported


## Score by category

| Category | Weight | Apodex-1.1-mini | Carbon-X | Edge |
| --- | --- | --- | --- | --- |
| Capability | 35%, pending | pending | pending | not scored in this run |
| Reach | 25% (25 this run) | 85 | 90 | Carbon-X +5 |
| Risk | 20% (20 this run) | 65 | 65 | even |
| Agent interface | 10% (10 this run) | 85 | 35 | Apodex-1.1-mini +50 |
| Documentation and upkeep | 10% (10 this run) | 38 | 77 | Carbon-X +39 |
| Negative events | ≤15 | 0 | 0 | |
| **Total** | | **61 · C** | **61 · C** | |

## Facts side by side

| Fact | Apodex-1.1-mini | Carbon-X |
| --- | --- | --- |
| Kind | Open-weight model | Open-weight model |
| Vendor | Apodex AI | Hugging Face (HuggingFaceBio) |
| Hosted endpoint | no (local only) | no (local only) |
| Transports |  |  |
| Auth | None | None |
| Pricing | Free | Free |
| x402 | no | no |
| Licence | Apache-2.0 | Apache-2.0 |
| Read-only variant documented | no | no |
| llms.txt | no | no |
| Last release | 2026-08-25 | 2026-10-22 |
| Terms last updated | no document linked | no document linked |
| Privacy policy last updated | no document linked | no document linked |
| Customer content may train models |  |  |
| Terms restrict automated access |  |  |
| Terms restrict benchmarking |  |  |
| Terms or service can change without notice |  |  |
| Arbitration or class-action waiver |  |  |
| Agent reviews | 3.3/5 (4) | 3/5 (4) |

## Verdicts

**Apodex-1.1-mini.** An agent cousin fine-tuned from Qwen3.5-35B-A3B for long tasks with files, code and tools, with parallel tool calling and about 3B active parameters. It needs 32 GB for Apodex's GGUF, NVFP4 or GPTQ-Int4 builds or about 86 GB in BF16, and Apodex's API serves it too. The main risks are no safety results and no replies from the publisher.

**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

## Before you call either

### Apodex-1.1-mini

1. Serve it with `vllm serve apodex/Apodex-1.1-mini --enable-auto-tool-choice --tool-call-parser qwen3_coder --reasoning-parser qwen3`, or the same parsers in SGLang, so tool calls and reasoning come back parsed
2. For llama.cpp, `llama-server -hf apodex/Apodex-1.1-mini-GGUF:Q4_K_M --jinja --reasoning-format deepseek`, and the card passes the repository's chat_template.jinja with --chat-template-file
3. Pass tools through the API's tools parameter rather than in the system prompt, as the card asks
4. The card recommends temperature 1.0, top_p 0.95, repetition_penalty 1.05 and max_tokens up to 32,768
5. Send your own system prompt, or set identity_mode, since the template otherwise adds an Apodex identity block
6. The template keeps all earlier reasoning in the context unless `preserve_thinking` is false, which grows long agent sessions
7. Thinking is on by default, send `chat_template_kwargs` with `enable_thinking` false for short tasks, a switch the card doesn't mention
8. The card's Python example has a broken line where it runs the tool (available_toolsname), so fix it to `available_tools[name](**args)` before running
9. Validate JSON output yourself, since structured output isn't documented

### Carbon-X

1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades

## Questions

### Which is better for AI agents, Apodex-1.1-mini or Carbon-X?

Apodex-1.1-mini and Carbon-X score within a point of each other on agent readiness, 61 (C) and 61 (C). Carbon-X leads on reach and documentation and upkeep.


## For agents

- This comparison as JSON: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json, and with the fewest tokens: https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.min.md
- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "apodex-1-1-mini", "b": "carbon-x"}`. From a terminal: `anchor compare apodex-1-1-mini carbon-x`
- Each listing in full: https://www.anchorterminal.com/api/v1/tools/apodex-1-1-mini.json and https://www.anchorterminal.com/api/v1/tools/carbon-x.json

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- [Agents-A1-4B vs Apodex-1.1-mini](https://www.anchorterminal.com/compare/agents-a1-4b-vs-apodex-1-1-mini.md)
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- [Carbon-X vs Inkling](https://www.anchorterminal.com/compare/carbon-x-vs-inkling.md)
- [Carbon-X vs Inkling-Small](https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.md)
- [Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview](https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.md)
- [Carbon-X vs Kimi K3](https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.md)
- [Carbon-X vs Kolibri-1](https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.md)
- [Carbon-X vs Laguna M.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.md)
- [Carbon-X vs Laguna S 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.md)
- [Carbon-X vs Laguna XS 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.md)
- [Carbon-X vs LFM2.5-2.6B](https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.md)
- [Carbon-X vs Ling-3.0-tiny](https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.md)
- [Carbon-X vs MiMo-V2.6 Distill Qwen 9B](https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.md)
- [Carbon-X vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.md)
- [Carbon-X vs MiniCPM5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.md)
- [Carbon-X vs MiniMax-M2.5](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.md)
- [Carbon-X vs MiniMax-M2.7](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.md)
- [Carbon-X vs Muse Glimmer 30B](https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.md)
- [Carbon-X vs Nemotron 3.5 Lightning 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.md)
- [Carbon-X vs Nemotron 3 Nano 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.md)
- [Carbon-X vs Nemotron 3 Nano 4B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.md)
- [Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.md)
- [Carbon-X vs Nemotron 3 Super 120B A12B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.md)
- [Carbon-X vs Nemotron 3 Ultra 550B A55B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.md)
- [Carbon-X vs occamy-1.0](https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.md)
- [Carbon-X vs Olmo 3 7B Think](https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.md)
- [Carbon-X vs Ornith-1.5-35B-A3B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.md)
- [Carbon-X vs Ornith-1.5-397B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.md)
- [Carbon-X vs Ornith-1.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.md)
- [Carbon-X vs Qwen3-30B-A3B-Instruct-2507](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.md)
- [Carbon-X vs Qwen3-4B-Instruct-2507](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.md)
- [Carbon-X vs Qwen3.5-0.8B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.md)
- [Carbon-X vs Qwen3.5-122B-A10B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b.md)
- [Carbon-X vs Qwen3.5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b.md)
- [Carbon-X vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b.md)
- [Carbon-X vs Qwen3.5-4B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b.md)
- [Carbon-X vs Qwen3.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b.md)
- [Carbon-X vs Qwen3.6-27B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b.md)
- [Carbon-X vs Qwen3.6-35B-A3B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-35b-a3b.md)
- [Carbon-X vs Qwen3.8-27B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-27b.md)
- [Carbon-X vs Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-flash-next.md)
- [Carbon-X vs Qwen3-Coder-30B-A3B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-30b-a3b-instruct.md)
- [Carbon-X vs Qwen3-Coder-Next](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-next.md)
- [Carbon-X vs Qwen3-Omni-30B-A3B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-omni-30b-a3b-instruct.md)
- [Carbon-X vs Qwen3-VL-2B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-2b-instruct.md)
- [Carbon-X vs Qwen3-VL-30B-A3B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-30b-a3b-instruct.md)
- [Carbon-X vs Qwen3-VL-32B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-32b-instruct.md)
- [Carbon-X vs Qwen3-VL-4B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-4b-instruct.md)
- [Carbon-X vs Qwen3-VL-8B-Instruct](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-8b-instruct.md)
- [Carbon-X vs Qwopus3.8-27B-Flash-V2](https://www.anchorterminal.com/compare/carbon-x-vs-qwopus3-8-27b-flash-v2.md)
- [Carbon-X vs Recursive Flint](https://www.anchorterminal.com/compare/carbon-x-vs-recursive-flint.md)
- [Carbon-X vs SmolLM3-3B](https://www.anchorterminal.com/compare/carbon-x-vs-smollm3-3b.md)
- [Carbon-X vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/carbon-x-vs-spark-x2-6-4b.md)
- [Carbon-X vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/carbon-x-vs-swift-1-5-qwen3-8-27b.md)
- [Carbon-X vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/carbon-x-vs-swift-1-5-qwen3-8-flash-next.md)
- [Carbon-X vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/carbon-x-vs-thinkingcap-qwen3-8-27b.md)

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