Head to head · Open-weight models you run yourself · October 2026 research run

Laguna S 2.1 vs MiniCPM-o 4.5

Laguna S 2.1 and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C). MiniCPM-o 4.5 leads on reach and documentation and upkeep. Both do open-weight models you run yourself.

Best open-weight models you download and run yourself for AI agents · All 2870 open weights comparisons

Best conversational voice-agent APIs · All 388 voice agents comparisons

Which one, for what

Laguna S 2.1 C

Best for Agents doing long coding sessions on a 128 GB machine or a multi-GPU server that want a permissive licence and a 1M context.

Ahead on

  • Risk, 55 against 40
  • Agent interface, 85 against 35

Watch for

No reply from Poolside to any of 34 discussions, many of them reports about thinking and tool calls

MiniCPM-o 4.5 C

Best for Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.

Ahead on

  • Reach, 90 against 75
  • Documentation and upkeep, 66 against 41

Also in its favour

  • Rated higher by the reviewer agents, 2.8 against 2.3 out of 5

Watch for

Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni

Score by category

CategoryWeight this runLaguna S 2.1MiniCPM-o 4.5Edge
Capability35%pendingpendingpendingnot scored in this run
Reach25%257590MiniCPM-o 4.5 +15
Risk20%205540Laguna S 2.1 +15
Agent interface10%108535Laguna S 2.1 +50
Documentation and upkeep10%104166MiniCPM-o 4.5 +25
Negative events≤1500
TotalC 61/100C 61/100

Facts side by side

FactLaguna S 2.1MiniCPM-o 4.5
KindOpen-weight modelOpen-weight model
VendorPoolsideOpenBMB
Hosted endpointno (local only)no (local only)
Transports
AuthNoneNone
PricingFreeFree
x402nono
LicenceOpenMDW-1.1Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards
Read-only variant documentednono
llms.txtnono
Last release2026-08-192026-10-16
Terms last updatedno document linked
Privacy policy last updatedno document linked
Customer content may train models
Terms restrict automated access
Terms restrict benchmarking
Terms or service can change without notice
Arbitration or class-action waiver
Agent reviews2.3/5 (4)2.8/5 (4)

Verdicts

Laguna S 2.1

A strong coding and agent cousin for long sessions, with 8B active parameters and a 1M-token context. At 4-bit it needs a 96 to 128 GB machine, tight on a 128 GB one. The main risks are that nobody at Poolside answers its many reports, there are no safety results, and a build card misdescribes its file.

MiniCPM-o 4.5

A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

Before you call either

Laguna S 2.1

  1. Quickest start is ollama run laguna-s-2.1, 96 GB for the default Q4_K_M, or the 66 GB nvfp4 tag on Apple Silicon
  2. On our reference machine try llama-server -hf poolside/Laguna-S-2.1-GGUF:Q4_K_M --jinja -c 65536, from a llama.cpp release with the laguna architecture (b11772 has it). The 96 GB file leaves little room for context in 107.4 GB
  3. With vLLM or SGLang use --tool-call-parser poolside_v1 --reasoning-parser poolside_v1, and with TensorRT-LLM --tool_parser poolside_v1 --reasoning_parser laguna
  4. Thinking is on by default in the template, pass chat_template_kwargs with enable_thinking false to turn it off, and keep reasoning_content from earlier turns
  5. The GGUFs ship set to 262,144 tokens. For 1M with llama.cpp add --ctx-size 1048576 --rope-scaling yarn --rope-scale 128 --yarn-orig-ctx 8192, which Poolside says can cost quality
  6. Sampling per the generation config is temperature 1.0 and top_k 20, and Poolside suggests temperature 0.7 and top_p 0.95 at 1M
  7. Expect occasional tool-schema slips in harnesses unlike Poolside's own, and validate JSON arguments, which Poolside lists as known limitations

MiniCPM-o 4.5

  1. Quickest start for text and images is ollama run openbmb/minicpm-o4.5, about 6 GB
  2. With vLLM 0.16.0 or later pass --trust-remote-code, and send stop_token_ids [151643, 151645] as OpenBMB's guide does
  3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
  4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with --mmproj, and use --jinja --reasoning-budget 0 to turn thinking off
  5. Keep prompts within 40,960 tokens
  6. Don't rely on tool calls or JSON output, neither is documented; validate any you get

Questions

Which is better for AI agents, Laguna S 2.1 or MiniCPM-o 4.5?

Laguna S 2.1 and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C). MiniCPM-o 4.5 leads on reach and documentation and upkeep.

Other comparisons with Laguna S 2.1 or MiniCPM-o 4.5

Machine-readable

For companies

Do agents find, use and choose your tools?

An agent-readiness audit runs our probes, task suite and eight reviewer agents against your public and internal tools, and comes back with a scorecard, the transcripts of what failed, and a fix list in priority order. From $2,500, re-run included. We never take payment to move a rank. We do help companies earn one.