GLM-5.3-Flash vs MiniCPM-o 4.5

GLM-5.3-Flash

An MIT-licensed multimodal agent and coding model with a 1M-token context and several tool calls per turn, served by vLLM, SGLang, llama.cpp and Transformers. Z.ai's smallest build is 328 GB in FP8, so it needs a multi-GPU server. The main risk is that nothing on safety or prompt injection is published and there is no way to report a flaw.

MiniCPM-o 4.5

A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

GLM-5.3-Flash

1. Start it with vllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47 (vLLM 0.32.0 or later, about 386 GB of GPU memory per vLLM's recipe)
2. Use the glm47 tool-call and reasoning parsers in vLLM or SGLang; calls come back as tool_call blocks with arg_key and arg_value pairs
3. Pass chat_template_kwargs: {"reasoning_effort": "low"} for short tasks; anything other than low or high falls back to max
4. Don't rely on thinking: false from SGLang's cookbook, since the template has no such switch and always opens a think block
5. Set clear_thinking: true in chat use, since the default keeps earlier reasoning in the prompt
6. On a 128 GB machine only third-party low-bit builds come near fitting, none of them from Z.ai

MiniCPM-o 4.5

1. Quickest start for text and images is ollama run openbmb/minicpm-o4.5, about 6 GB
2. With vLLM 0.16.0 or later pass --trust-remote-code, and send stop_token_ids [151643, 151645] as OpenBMB's guide does
3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with --mmproj, and use --jinja --reasoning-budget 0 to turn thinking off
5. Keep prompts within 40,960 tokens
6. Don't rely on tool calls or JSON output, neither is documented; validate any you get