MiniCPM-o 4.5 vs NVIDIA Nemotron 3.5 Bolt E4B 4GB

MiniCPM-o 4.5

A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

NVIDIA Nemotron 3.5 Bolt E4B 4GB

A small cousin for voice and device assistants, game characters and robot interfaces, trained for multi-turn tool calls, instruction hierarchy and short spoken replies, with thinking switchable per request. NVIDIA's Q4_K_M GGUF needs about 8 GB, and Ollama and LM Studio carry it. Context is 64K, half the Gemma 4 base, and NVIDIA publishes no safety results.

MiniCPM-o 4.5

1. Quickest start for text and images is ollama run openbmb/minicpm-o4.5, about 6 GB
2. With vLLM 0.16.0 or later pass --trust-remote-code, and send stop_token_ids [151643, 151645] as OpenBMB's guide does
3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with --mmproj, and use --jinja --reasoning-budget 0 to turn thinking off
5. Keep prompts within 40,960 tokens
6. Don't rely on tool calls or JSON output, neither is documented; validate any you get

NVIDIA Nemotron 3.5 Bolt E4B 4GB

1. Quickest start is ollama run nemotron-3.5-bolt:e4b, about 8 GB of files, and set num_ctx to 65536 or less, since NVIDIA supports 64K
2. With NVIDIA's GGUF use llama-server -m Nemotron-3.5-Bolt-E4B-Q4_K_M.gguf -c 65536 -ngl 999 --jinja, and add --reasoning on --reasoning-budget <tokens> to cap thinking
3. With vLLM 0.31.0 or later pass --enable-auto-tool-choice --tool-call-parser gemma4 --reasoning-parser gemma4 and the repository's chat_template.jinja
4. Pass enable_thinking explicitly in chat_template_kwargs, since the template defaults to off whatever the card says, and set skip_special_tokens false as the card's examples do
5. Use temperature=1.0 and top_p=0.95 in both modes, as the card says
6. Set conversational_mode true for spoken replies, which appends a brevity instruction to the system prompt
7. Answer a slow tool at once with a pending tool message, then send the result later as a user message starting TOOL RESULT, as the card's asynchronous pattern says
8. Keep persistent rules in the system prompt and send state updates as separate user or system messages in order, per the card's prompting guidelines