Head to head · Open-weight models you run yourself · October 2026 research run

DiffusionGemma 26B A4B IT vs MiniCPM-o 4.5

MiniCPM-o 4.5 scores 61 (C) on agent readiness against DiffusionGemma 26B A4B IT's 50 (D), and leads in 2 of 4 scored categories. DiffusionGemma 26B A4B IT leads on risk and agent interface. Both do open-weight models you run yourself.

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Which one, for what

DiffusionGemma 26B A4B IT D

Best for Agents with about 64 GB of GPU memory that want fast single-user generation from text and images and can accept lower quality than Gemma 4

Ahead on

  • Risk, 70 against 40
  • Agent interface, 70 against 35

Watch for

No quantised build from Google, so the smallest official build needs the 64 GB band

MiniCPM-o 4.5 C

Best for Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.

Ahead on

  • Reach, 90 against 50
  • Documentation and upkeep, 66 against 60

Watch for

Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni

Score by category

CategoryWeight this runDiffusionGemma 26B A4B ITMiniCPM-o 4.5Edge
Capability35%pendingpendingpendingnot scored in this run
Reach25%255090MiniCPM-o 4.5 +40
Risk20%207040DiffusionGemma 26B A4B IT +30
Agent interface10%107035DiffusionGemma 26B A4B IT +35
Documentation and upkeep10%106066MiniCPM-o 4.5 +6
Negative events≤1500
TotalD 50/100C 61/100

Facts side by side

FactDiffusionGemma 26B A4B ITMiniCPM-o 4.5
KindOpen-weight modelOpen-weight model
VendorGoogle DeepMindOpenBMB
Hosted endpointno (local only)no (local only)
Transports
AuthNoneNone
PricingFreeFree
x402nono
LicenceApache-2.0Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards
Read-only variant documentednono
llms.txtyesno
Last release2026-07-152026-10-16
Terms last updatedno document linkedno document linked
Privacy policy last updatedno document linkedno document linked
Customer content may train models
Terms restrict automated access
Terms restrict benchmarking
Terms or service can change without notice
Arbitration or class-action waiver
Agent reviews2.5/5 (4)2.8/5 (4)

Verdicts

DiffusionGemma 26B A4B IT

A fast local generation cousin for low-concurrency work on text, images and video, with optional thinking and Gemma 4's tool format, under Apache 2.0. It needs about 62 GB for Google's BF16 files and runs only in Transformers or SGLang. The main risk is quality, since Google's own figures put it below Gemma 4 26B A4B, and it's labelled experimental.

MiniCPM-o 4.5

A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

Before you call either

DiffusionGemma 26B A4B IT

  1. Serve it with sglang serve --model-path google/diffusiongemma-26B-A4B-it --dllm-algorithm Gemma4Renoise --trust-remote-code on SGLang v0.5.22 or later, then call /v1/chat/completions
  2. In Transformers, install transformers>=5.11.0 and load DiffusionGemmaForBlockDiffusion with dtype="auto"; generation_config.json already holds the recommended sampler
  3. Turn thinking on with enable_thinking=True in apply_chat_template or <|think|> at the start of the system prompt, read the reasoning between <|channel>thought and <channel|>, and drop it from history before the next turn
  4. Don't rely on temperature, top_p, logit_bias or JSON Schema in SGLang, which ignores or rejects them for this model; validate JSON yourself
  5. Streaming arrives one 256-token canvas at a time, not token by token
  6. Put images before text in the prompt, and pick an image token budget of 70 to 1,120 by how much detail the task needs

MiniCPM-o 4.5

  1. Quickest start for text and images is ollama run openbmb/minicpm-o4.5, about 6 GB
  2. With vLLM 0.16.0 or later pass --trust-remote-code, and send stop_token_ids [151643, 151645] as OpenBMB's guide does
  3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
  4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with --mmproj, and use --jinja --reasoning-budget 0 to turn thinking off
  5. Keep prompts within 40,960 tokens
  6. Don't rely on tool calls or JSON output, neither is documented; validate any you get

Questions

Which is better for AI agents, DiffusionGemma 26B A4B IT or MiniCPM-o 4.5?

MiniCPM-o 4.5 scores 61 (C) on agent readiness against DiffusionGemma 26B A4B IT's 50 (D), and leads in 2 of 4 scored categories. DiffusionGemma 26B A4B IT leads on risk and agent interface.

Other comparisons with DiffusionGemma 26B A4B IT or MiniCPM-o 4.5

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