Gemma 4 E4B IT vs GLM-5.3-Flash

Gemma 4 E4B IT

A small cousin for light agent work, tool-calling loops, transcription and image reading on a phone or laptop, under Apache 2.0. Google's 4-bit build needs about 7 GB with working space and runs in all the common runtimes. Google's card puts it far below larger Gemma 4 sizes on agent and coding tasks, with no published safety results.

GLM-5.3-Flash

An MIT-licensed multimodal agent and coding model with a 1M-token context and several tool calls per turn, served by vLLM, SGLang, llama.cpp and Transformers. Z.ai's smallest build is 328 GB in FP8, so it needs a multi-GPU server. The main risk is that nothing on safety or prompt injection is published and there is no way to report a flaw.

Gemma 4 E4B IT

1. On the reference machine run llama-server -hf google/gemma-4-E4B-it-qat-q4_0-gguf --hf-file gemma-4-E4B_q4_0-it.gguf --jinja -c 131072, and add --mmproj with gemma-4-E4B-it-mmproj.gguf for images and audio
2. With Ollama run ollama run gemma4:e4b and raise num_ctx or OLLAMA_CONTEXT_LENGTH, since the default context is small and agents want at least 64K
3. In vLLM or SGLang pass --tool-call-parser gemma4 --reasoning-parser gemma4 (vLLM also --enable-auto-tool-choice), or tool calls come back as text; Google's w4a16 build is the 4-bit route there
4. Thinking is off by default; pass enable_thinking=True or start the system prompt with <|think|>, and drop earlier turns' thinking from history except on tool-call turns
5. Put images before the text and audio after it, keep audio to 30 seconds and video to 60 frames, and validate tool names and arguments before running them

GLM-5.3-Flash

1. Start it with vllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47 (vLLM 0.32.0 or later, about 386 GB of GPU memory per vLLM's recipe)
2. Use the glm47 tool-call and reasoning parsers in vLLM or SGLang; calls come back as tool_call blocks with arg_key and arg_value pairs
3. Pass chat_template_kwargs: {"reasoning_effort": "low"} for short tasks; anything other than low or high falls back to max
4. Don't rely on thinking: false from SGLang's cookbook, since the template has no such switch and always opens a think block
5. Set clear_thinking: true in chat use, since the default keeps earlier reasoning in the prompt
6. On a 128 GB machine only third-party low-bit builds come near fitting, none of them from Z.ai