Qwen3.5-397B-A17B vs Qwen3.8-27B

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Qwen3.8-27B

A dense cousin for coding and agent work with image and video input that runs almost anywhere. Ollama's 4-bit build needs about 22 GB, and five providers host it for agents without the hardware. The main risk is that nobody at Alibaba answers, there are no safety results or agent guidance, and the tool format is only in the template.

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented

Qwen3.8-27B

1. Quickest start is ollama run qwen3.8, about 18 GB of files
2. On our reference machine use BF16 with vllm serve Qwen/Qwen3.8-27B --max-model-len 131072 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, since FP8 on gfx1151 isn't documented
3. Use the qwen3_coder tool parser, SGLang's cookbook says the Hermes parser leaves its calls unparsed
4. Thinking is on by default, pass chat_template_kwargs with enable_thinking false for short tasks, and read the reasoning from reasoning_content
5. reasoning_effort takes xhigh (default), medium or low, and any other value makes the template raise an error
6. Sampling per the card is temperature 1.0 and top_p 0.95 when thinking, temperature 0.7, top_p 0.8 and presence_penalty 1.5 without
7. Preserved thinking keeps earlier reasoning in the context unless preserve_thinking is false, which grows long agent sessions
8. Turn on YaRN only beyond 262,144 tokens, the card warns static YaRN can cost quality on short texts
9. Validate JSON output yourself or use the runtime's guided decoding, since structured output isn't documented