Qwen3.5-397B-A17B vs Qwen3.6-27B

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Qwen3.6-27B

A capable dense cousin for agentic coding and tool calls with images and video in, running in every major runtime. Ollama's 4-bit build needs about 22 GB, and three providers host it. The main risk is silence, with no safety results, no agent guidance, no answers in its repository and Qwen3.8-27B now ahead of it.

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented

Qwen3.6-27B

1. Quickest start is ollama run qwen3.6:27b, about 18 GB of files with the vision projector
2. Alibaba's FP8 build with the card's parsers is vllm serve Qwen/Qwen3.6-27B-FP8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, vllm 0.19.0 or later
3. Use the qwen3_coder tool parser, the template writes calls as function and parameter blocks inside tool_call
4. Thinking is on by default, pass "chat_template_kwargs": {"enable_thinking": false} for short tasks, and /think and /nothink aren't supported
5. "preserve_thinking": true in chat_template_kwargs keeps earlier reasoning in context, which helps long agent sessions but grows the prompt
6. Sampling per the card is temperature 1.0, top_p 0.95, top_k 20 when thinking, and temperature 0.7, top_p 0.8, presence_penalty 1.5 without
7. Keep at least 128K of context if you rely on thinking, and turn on YaRN only beyond 262,144 tokens
8. Validate any JSON it returns or use the runtime's guided decoding, since structured output isn't documented
9. Qwen3.8-27B (listed as qwen3-8-27b) is the newer model at this size on the same runtimes