Qwen3.5-397B-A17B vs Qwen3-Omni-30B-A3B-Instruct

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Qwen3-Omni-30B-A3B-Instruct

An omni-modal cousin that listens, watches and reads, then answers in text or one of three voices, with tool calls from spoken requests, under plain Apache 2.0. Its only build, BF16, needs about 85 GB, and speech out needs Transformers or vLLM-Omni. The main risk is no answers from Qwen and no safety work for speech-driven actions.

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented

Qwen3-Omni-30B-A3B-Instruct

1. For text answers, mkdir -p media && vllm serve Qwen/Qwen3-Omni-30B-A3B-Instruct --dtype bfloat16 --max-model-len 32768 --allowed-local-media-path "$(pwd)/media" with vLLM 0.11.1 or later serves the Thinker on an OpenAI-compatible API
2. The card's command passes --allowed-local-media-path /, which lets anyone who can reach the server have it read any file on the machine through a file:// URL. Point it at a dedicated folder that holds only the media you mean to send, as above, and give vLLM an absolute path
3. Send audio as audio_url and images as image_url content parts; vLLM serve doesn't take use_audio_in_video, so pass a video's audio separately
4. For speech out, load Qwen3OmniMoeForConditionalGeneration in Transformers 4.57.0 or later with qwen-omni-utils, pick speaker Ethan, Chelsie or Aiden, and write the returned waveform at 24 kHz
5. Call model.disable_talker() or pass return_audio=False when you only need text, which saves about 10 GB and time
6. Parse tool calls as JSON inside <tool_call> tags yourself, since no parser is named, and confirm actions triggered by speech before running them
7. Keep use_audio_in_video the same across every step of a conversation, the card warns results go wrong otherwise
8. Budget memory for video, the card's table rises from 78.85 GB for 15 seconds to 144.81 GB for 120 seconds in BF16