Laguna M.1 vs Qwen3.5-397B-A17B

Laguna M.1

A large coding and agent cousin under plain Apache 2.0, for agents with a multi-GPU server. Its smallest build needs about 167 GB, more than a 128 GB machine, and no local runtime library packages it. The main risks are no upkeep since July, no hosted fallback shown today, no safety results, and repository code on the SGLang route.

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Laguna M.1

1. Run the NVFP4 build on Blackwell GPUs with vllm serve poolside/Laguna-M.1-NVFP4 --tensor-parallel-size 2 --tool-call-parser poolside_v1 --reasoning-parser poolside_v1 --enable-auto-tool-choice, on vLLM 0.21.0 or later
2. Thinking is off in the template unless you pass enable_thinking true or start the server with --default-chat-template-kwargs '{"enable_thinking": true}', which Poolside recommends for agentic coding
3. Pass earlier reasoning back as reasoning_content in the history, since the card says reasoning may stop in later steps if it's dropped
4. Sampling per the card is temperature 1.0 and top_k 20
5. The FP8 build's Docker image and serve.sh predate upstream support and set a 4,096-token context, so prefer a released vLLM
6. It doesn't fit our 128 GB reference machine at any published precision
7. Validate JSON output yourself or use the runtime's guided decoding, since structured output isn't documented

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented