Laguna M.1 vs Qwen3.5-122B-A10B

Laguna M.1

A large coding and agent cousin under plain Apache 2.0, for agents with a multi-GPU server. Its smallest build needs about 167 GB, more than a 128 GB machine, and no local runtime library packages it. The main risks are no upkeep since July, no hosted fallback shown today, no safety results, and repository code on the SGLang route.

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Laguna M.1

1. Run the NVFP4 build on Blackwell GPUs with vllm serve poolside/Laguna-M.1-NVFP4 --tensor-parallel-size 2 --tool-call-parser poolside_v1 --reasoning-parser poolside_v1 --enable-auto-tool-choice, on vLLM 0.21.0 or later
2. Thinking is off in the template unless you pass enable_thinking true or start the server with --default-chat-template-kwargs '{"enable_thinking": true}', which Poolside recommends for agentic coding
3. Pass earlier reasoning back as reasoning_content in the history, since the card says reasoning may stop in later steps if it's dropped
4. Sampling per the card is temperature 1.0 and top_k 20
5. The FP8 build's Docker image and serve.sh predate upstream support and set a 4,096-token context, so prefer a released vLLM
6. It doesn't fit our 128 GB reference machine at any published precision
7. Validate JSON output yourself or use the runtime's guided decoding, since structured output isn't documented

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented