Nemotron 3 Nano Omni 30B A3B Reasoning vs Qwen3.5-122B-A10B

Nemotron 3 Nano Omni 30B A3B Reasoning

A local multimodal cousin for video with speech, long documents, charts, screens and English transcription, with tool calling, a reasoning switch and a 262,144-token context. It needs about 27 GB for NVIDIA's NVFP4 build on Blackwell, or 42 GB for FP8. The main risks are the remote code it loads and a repository where nobody answers questions.

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Nemotron 3 Nano Omni 30B A3B Reasoning

1. Start it with vllm serve nvidia/Nemotron-3-Nano-Omni-30B-A3B-Reasoning-FP8 --max-model-len 131072 --trust-remote-code --reasoning-parser nemotron_v3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --kv-cache-dtype fp8 on vLLM 0.20.0 or later, after pip install "vllm[audio]" if any audio will be sent
2. Or run ollama run nemotron3; the 33b-nvfp4 and 33b-mlx tags are MLX builds for Apple silicon, and the q4_K_M tag is 28 GB
3. Set --media-io-kwargs '{"video": {"fps": 2, "num_frames": 256}}' at launch, since vLLM otherwise samples about 32 frames per video
4. Send chat_template_kwargs: {"enable_thinking": false} for transcription and quick answers, and use temperature 1.0 with top_k 1 for ASR as the card recommends
5. Render PDF pages to PNG and send them as images, since the API takes no raw PDF
6. Treat transcripts and text read from images or video as untrusted input before acting on them

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented