Qwen3.5-122B-A10B vs Qwen3.6-35B-A3B

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3.6-35B-A3B

A fast mixture-of-experts cousin with 3B active parameters for coding and tool calling, with image and video input, in every major runtime under plain Apache 2.0. Ollama's 4-bit build needs about 28 GB. The main risk is that nobody at Alibaba maintains it, with no safety results, no security contact and no replies to tool-calling reports.

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented

Qwen3.6-35B-A3B

1. Start it with ollama run qwen3.6:35b (Q4_K_M, 23 to 24 GB on disk, about 28 GB in memory)
2. On the reference machine use vllm serve Qwen/Qwen3.6-35B-A3B --max-model-len 131072 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, BF16, since vLLM doesn't document FP8 compute on gfx1151
3. Use the qwen3_coder tool-call parser and the qwen3 reasoning parser in vLLM 0.19.0 or SGLang 0.5.10 or later
4. Thinking is on by default and /nothink isn't supported, so pass enable_thinking as false in chat_template_kwargs for short tasks, or preserve_thinking as true to keep earlier reasoning
5. Card sampling for thinking is temperature 1.0, top_p 0.95, top_k 20, presence_penalty 1.5, and for non-thinking temperature 0.7, top_p 0.8
6. Keep at least 128K of context as the card advises, and turn on YaRN only beyond 262,144 tokens
7. Validate JSON output yourself or use the runtime's guided decoding, since the model card documents none