Qwen3.5-122B-A10B vs Qwen3-Omni-30B-A3B-Instruct

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3-Omni-30B-A3B-Instruct

An omni-modal cousin that listens, watches and reads, then answers in text or one of three voices, with tool calls from spoken requests, under plain Apache 2.0. Its only build, BF16, needs about 85 GB, and speech out needs Transformers or vLLM-Omni. The main risk is no answers from Qwen and no safety work for speech-driven actions.

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented

Qwen3-Omni-30B-A3B-Instruct

1. For text answers, mkdir -p media && vllm serve Qwen/Qwen3-Omni-30B-A3B-Instruct --dtype bfloat16 --max-model-len 32768 --allowed-local-media-path "$(pwd)/media" with vLLM 0.11.1 or later serves the Thinker on an OpenAI-compatible API
2. The card's command passes --allowed-local-media-path /, which lets anyone who can reach the server have it read any file on the machine through a file:// URL. Point it at a dedicated folder that holds only the media you mean to send, as above, and give vLLM an absolute path
3. Send audio as audio_url and images as image_url content parts; vLLM serve doesn't take use_audio_in_video, so pass a video's audio separately
4. For speech out, load Qwen3OmniMoeForConditionalGeneration in Transformers 4.57.0 or later with qwen-omni-utils, pick speaker Ethan, Chelsie or Aiden, and write the returned waveform at 24 kHz
5. Call model.disable_talker() or pass return_audio=False when you only need text, which saves about 10 GB and time
6. Parse tool calls as JSON inside <tool_call> tags yourself, since no parser is named, and confirm actions triggered by speech before running them
7. Keep use_audio_in_video the same across every step of a conversation, the card warns results go wrong otherwise
8. Budget memory for video, the card's table rises from 78.85 GB for 15 seconds to 144.81 GB for 120 seconds in BF16