Qwen3.5-122B-A10B vs Qwen3.5-2B

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3.5-2B

A small vision-language cousin for prototypes, fine-tuning and light local steps such as tool calls, tagging or reading an image, running in about 2 GB at 4 bits in every major runtime under plain Apache 2.0. Keep thinking off, since the card warns it loops. The main risk is neglect, with no safety results or answers from Alibaba since March.

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented

Qwen3.5-2B

1. Smallest start is ollama run qwen3.5:2b-q4_K_M (1.9 GB); plain qwen3.5:2b pulls the 2.7 GB Q8_0 build
2. Full precision vllm serve Qwen/Qwen3.5-2B --port 8000 --max-model-len 262144 --enable-auto-tool-choice --tool-call-parser qwen3_coder
3. Thinking is off by default; if you turn it on with "chat_template_kwargs": {"enable_thinking": true}, stream and cut off runaway output, since the card warns of thinking loops, and add --reasoning-parser qwen3 in vLLM or SGLang to split the reasoning out
4. There's no generation_config.json, so pass the card's sampling yourself, for example temperature=1.0, top_p=1.0, top_k=20, presence_penalty=2.0 for text without thinking
5. Use it for narrow steps or as a fine-tuning base, not as the main agent, as the card itself suggests
6. Validate any JSON it returns, since structured output isn't documented