Qwen3.5-122B-A10B vs Qwen3-VL-8B-Instruct

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3-VL-8B-Instruct

A small vision-language cousin for reading screenshots, documents, charts and video, in about 6 GB from Alibaba's Q4_K_M GGUF and every major runtime, under plain Apache 2.0. It has no thinking mode and documents tool calls only in the template. The main risk is no published safety work, so add your own guardrails before it drives a GUI.

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented

Qwen3-VL-8B-Instruct

1. Start it with llama-server -hf Qwen/Qwen3-VL-8B-Instruct-GGUF:Q4_K_M --jinja -c 32768, or ollama run qwen3-vl:8b-instruct
2. In Ollama the plain qwen3-vl:8b tag is the Thinking edition, so name 8b-instruct
3. With the GGUF, load the mmproj vision file too, or images won't be read
4. Parse tool calls as JSON inside <tool_call> tags, or use SGLang's --tool-call-parser qwen
5. Use the card's sampling, temperature=0.7, top_p=0.8, top_k=20, presence_penalty=1.5 for vision and temperature=1.0, top_p=1.0, top_k=40, presence_penalty=2.0 for text
6. Validate JSON output yourself, since structured output isn't documented
7. vLLM needs 0.11.0 or later and Transformers 4.57.0 or later