Qwen3.5-122B-A10B vs Qwen3.6-27B

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3.6-27B

A capable dense cousin for agentic coding and tool calls with images and video in, running in every major runtime. Ollama's 4-bit build needs about 22 GB, and three providers host it. The main risk is silence, with no safety results, no agent guidance, no answers in its repository and Qwen3.8-27B now ahead of it.

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented

Qwen3.6-27B

1. Quickest start is ollama run qwen3.6:27b, about 18 GB of files with the vision projector
2. Alibaba's FP8 build with the card's parsers is vllm serve Qwen/Qwen3.6-27B-FP8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, vllm 0.19.0 or later
3. Use the qwen3_coder tool parser, the template writes calls as function and parameter blocks inside tool_call
4. Thinking is on by default, pass "chat_template_kwargs": {"enable_thinking": false} for short tasks, and /think and /nothink aren't supported
5. "preserve_thinking": true in chat_template_kwargs keeps earlier reasoning in context, which helps long agent sessions but grows the prompt
6. Sampling per the card is temperature 1.0, top_p 0.95, top_k 20 when thinking, and temperature 0.7, top_p 0.8, presence_penalty 1.5 without
7. Keep at least 128K of context if you rely on thinking, and turn on YaRN only beyond 262,144 tokens
8. Validate any JSON it returns or use the runtime's guided decoding, since structured output isn't documented
9. Qwen3.8-27B (listed as qwen3-8-27b) is the newer model at this size on the same runtimes