Qwen3-4B-Instruct-2507 vs Qwen3.5-122B-A10B

Qwen3-4B-Instruct-2507

A small, fast cousin for instruction following, short tool-calling jobs and long documents on modest hardware, with no thinking step. It runs in about 3 GB at 4 bits on every common runtime, and two providers host it. The main risk is neglect, with no file changes in over a year, no answers from Alibaba and no safety results.

Qwen3.5-122B-A10B

A strong mid-size cousin for coding, agent steps and reading images or video, with thinking you can switch off per request. Alibaba's 4-bit build needs about 95 GB, which fits one 128 GB unified-memory machine, and several providers host it. The main risk is silence, with no safety results, agent guidance or answers from Alibaba.

Qwen3-4B-Instruct-2507

1. Quickest start is ollama run qwen3:4b-instruct, 2.5 GB. Plain qwen3:4b is the Thinking-2507 edition, not this one
2. On our reference machine use BF16 with vllm serve Qwen/Qwen3-4B-Instruct-2507 --max-model-len 262144 --enable-auto-tool-choice --tool-call-parser hermes
3. Use the hermes parser in vLLM or qwen25 in SGLang, the template emits JSON inside tool_call tags
4. Don't pass enable_thinking, this edition never thinks and the card says the flag isn't needed
5. Sampling per the card is temperature 0.7, top_p 0.8, top_k 20 and min_p 0, with presence_penalty up to 2 against repetition
6. Drop the context to 32,768 tokens if memory runs out, as the card suggests
7. Validate JSON yourself or use the runtime's guided decoding, since structured output isn't documented

Qwen3.5-122B-A10B

1. Quickest start on a 128 GB machine is ollama run qwen3.5:122b (Q4_K_M, 81 GB of files, about 97 GB with context)
2. Alibaba's 4-bit build serves with vllm serve Qwen/Qwen3.5-122B-A10B-GPTQ-Int4 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder --quantization moe_wna16, though that kernel isn't documented for AMD gfx1151
3. Use the qwen3_coder tool parser and the qwen3 reasoning parser, as the card's commands do
4. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
5. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Add --language-model-only in vLLM to skip the vision encoder and free memory for the KV cache when you only need text
8. Validate any JSON it returns, since structured output isn't documented