Mistral Large 4 vs Qwen3-4B-Instruct-2507

Mistral Large 4

A frontier-sized open cousin for coding agents and defensive security, with strict JSON Schema output, parallel tool calls and three reasoning efforts. It needs a multi-GPU server, about 732 GB for the smallest 4-bit build, and vLLM and SGLang run it only from special images. The main risk is a licence that bars Model-as-a-Service businesses without a separate deal.

Qwen3-4B-Instruct-2507

A small, fast cousin for instruction following, short tool-calling jobs and long documents on modest hardware, with no thinking step. It runs in about 3 GB at 4 bits on every common runtime, and two providers host it. The main risk is neglect, with no file changes in over a year, no answers from Alibaba and no safety results.

Mistral Large 4

1. Serve the NVFP4 build on Blackwell with vllm/vllm-openai:mistral-large-4 --model mistralai/Mistral-Large-4-1T-A52B-NVFP4 --tensor-parallel-size 8 --kv-cache-dtype fp8_ds_mla --tool-call-parser mistral --reasoning-parser mistral --enable-auto-tool-choice; released vLLM doesn't load it
2. On H200 use the FP8 build with tensor parallelism of 16 or 8 by 2 pipelines, per vLLM's recipe
3. Pass reasoning_effort low, medium or high (default high); any other value makes the template raise an error, and there is no off switch
4. Read the reasoning from message.reasoning; max_completion_tokens counts reasoning tokens too
5. Use temperature 1.0 and top_p 0.95 at every effort, per the card
6. Ask for JSON with response_format type json_schema and strict true; the template passes the schema to the model
7. The template rejects a tool message straight after a user message and a conversation that doesn't start with a user or system message
8. Add --speculative-config '{"method": "dspark", "num_speculative_tokens": 3}' to use the embedded draft head
9. If you'll offer it to others as a hosted model, read the licence first; Model-as-a-Service use needs Mistral's commercial licence

Qwen3-4B-Instruct-2507

1. Quickest start is ollama run qwen3:4b-instruct, 2.5 GB. Plain qwen3:4b is the Thinking-2507 edition, not this one
2. On our reference machine use BF16 with vllm serve Qwen/Qwen3-4B-Instruct-2507 --max-model-len 262144 --enable-auto-tool-choice --tool-call-parser hermes
3. Use the hermes parser in vLLM or qwen25 in SGLang, the template emits JSON inside tool_call tags
4. Don't pass enable_thinking, this edition never thinks and the card says the flag isn't needed
5. Sampling per the card is temperature 0.7, top_p 0.8, top_k 20 and min_p 0, with presence_penalty up to 2 against repetition
6. Drop the context to 32,768 tokens if memory runs out, as the card suggests
7. Validate JSON yourself or use the runtime's guided decoding, since structured output isn't documented