Darwin-36B-Opus vs Mistral Large 4

Darwin-36B-Opus

A text-only reasoning cousin merged from Qwen3.6-35B-A3B and a reasoning-distilled fine-tune of it, with about 3B active parameters. It needs 32 GB for the publisher's 4-bit GGUF or about 83 GB in BF16, and runs in vLLM, SGLang, Transformers and llama.cpp. The main risks are an undisclosed merge method, a card that disagrees with its files, and no safety results.

Mistral Large 4

A frontier-sized open cousin for coding agents and defensive security, with strict JSON Schema output, parallel tool calls and three reasoning efforts. It needs a multi-GPU server, about 732 GB for the smallest 4-bit build, and vLLM and SGLang run it only from special images. The main risk is a licence that bars Model-as-a-Service businesses without a separate deal.

Darwin-36B-Opus

1. Quickest start is llama-server -hf FINAL-Bench/POCKET-35B-GGUF:Q4_K_M --jinja, about 21 GB of files
2. On the reference machine BF16 fits, vllm serve FINAL-Bench/Darwin-36B-Opus --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, the parsers for Qwen3.6's format
3. Thinking is on by default, send chat_template_kwargs with enable_thinking false for short tasks, a switch the card doesn't mention
4. The card suggests temperature 0.6 to 0.7 and at least 5,120 new tokens for its think traces
5. generation_config.json stops only on the end-of-text token, so add <|im_end|> as a stop token if a runtime keeps generating after the turn ends
6. Text only, the vision encoder of Qwen3.6-35B-A3B isn't in these files
7. Validate JSON output yourself, since structured output isn't documented

Mistral Large 4

1. Serve the NVFP4 build on Blackwell with vllm/vllm-openai:mistral-large-4 --model mistralai/Mistral-Large-4-1T-A52B-NVFP4 --tensor-parallel-size 8 --kv-cache-dtype fp8_ds_mla --tool-call-parser mistral --reasoning-parser mistral --enable-auto-tool-choice; released vLLM doesn't load it
2. On H200 use the FP8 build with tensor parallelism of 16 or 8 by 2 pipelines, per vLLM's recipe
3. Pass reasoning_effort low, medium or high (default high); any other value makes the template raise an error, and there is no off switch
4. Read the reasoning from message.reasoning; max_completion_tokens counts reasoning tokens too
5. Use temperature 1.0 and top_p 0.95 at every effort, per the card
6. Ask for JSON with response_format type json_schema and strict true; the template passes the schema to the model
7. The template rejects a tool message straight after a user message and a conversation that doesn't start with a user or system message
8. Add --speculative-config '{"method": "dspark", "num_speculative_tokens": 3}' to use the embedded draft head
9. If you'll offer it to others as a hosted model, read the licence first; Model-as-a-Service use needs Mistral's commercial licence