Mistral Large 4 vs Nemotron 3 Super 120B A12B

Mistral Large 4

A frontier-sized open cousin for coding agents and defensive security, with strict JSON Schema output, parallel tool calls and three reasoning efforts. It needs a multi-GPU server, about 732 GB for the smallest 4-bit build, and vLLM and SGLang run it only from special images. The main risk is a licence that bars Model-as-a-Service businesses without a separate deal.

Nemotron 3 Super 120B A12B

A long-context agent cousin with trained parallel tool calls, a reasoning switch and a full account of its training data, under a free commercial licence. It needs about 100 GB of GPU memory, a 128 GB unified machine or Blackwell hardware for NVIDIA's NVFP4. The main risks are serving commands that run repository code and no published safety results.

Mistral Large 4

1. Serve the NVFP4 build on Blackwell with vllm/vllm-openai:mistral-large-4 --model mistralai/Mistral-Large-4-1T-A52B-NVFP4 --tensor-parallel-size 8 --kv-cache-dtype fp8_ds_mla --tool-call-parser mistral --reasoning-parser mistral --enable-auto-tool-choice; released vLLM doesn't load it
2. On H200 use the FP8 build with tensor parallelism of 16 or 8 by 2 pipelines, per vLLM's recipe
3. Pass reasoning_effort low, medium or high (default high); any other value makes the template raise an error, and there is no off switch
4. Read the reasoning from message.reasoning; max_completion_tokens counts reasoning tokens too
5. Use temperature 1.0 and top_p 0.95 at every effort, per the card
6. Ask for JSON with response_format type json_schema and strict true; the template passes the schema to the model
7. The template rejects a tool message straight after a user message and a conversation that doesn't start with a user or system message
8. Add --speculative-config '{"method": "dspark", "num_speculative_tokens": 3}' to use the embedded draft head
9. If you'll offer it to others as a hosted model, read the licence first; Model-as-a-Service use needs Mistral's commercial licence

Nemotron 3 Super 120B A12B

1. On the reference machine start it with ollama run nemotron-3-super, the 87 GB q4_K_M build, the only one that fits (about 104 GB with the margin)
2. Raise the Strix Halo GPU memory limit first with amd-ttm --set 100, since the default of about 62.8 GiB is far below what it needs
3. With vLLM serve it with --reasoning-parser nemotron_v3 --enable-auto-tool-choice --tool-call-parser qwen3_coder (SGLang uses --reasoning-parser nemotron_3)
4. Use temperature=1.0 and top_p=0.95 for every task, as the card says
5. Thinking is on by default. Pass enable_thinking: false or low_effort: true in chat_template_kwargs for short tasks
6. For coding agents pass force_nonempty_content: true in chat_template_kwargs, so a cut-off reasoning trace still returns content
7. Raise context past 262,144 only with the card's flags (VLLM_ALLOW_LONG_MAX_MODEL_LEN=1, --max-model-len 1048576)