Qwen3-4B-Instruct-2507 vs Qwen3.5-397B-A17B

Qwen3-4B-Instruct-2507

A small, fast cousin for instruction following, short tool-calling jobs and long documents on modest hardware, with no thinking step. It runs in about 3 GB at 4 bits on every common runtime, and two providers host it. The main risk is neglect, with no file changes in over a year, no answers from Alibaba and no safety results.

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Qwen3-4B-Instruct-2507

1. Quickest start is ollama run qwen3:4b-instruct, 2.5 GB. Plain qwen3:4b is the Thinking-2507 edition, not this one
2. On our reference machine use BF16 with vllm serve Qwen/Qwen3-4B-Instruct-2507 --max-model-len 262144 --enable-auto-tool-choice --tool-call-parser hermes
3. Use the hermes parser in vLLM or qwen25 in SGLang, the template emits JSON inside tool_call tags
4. Don't pass enable_thinking, this edition never thinks and the card says the flag isn't needed
5. Sampling per the card is temperature 0.7, top_p 0.8, top_k 20 and min_p 0, with presence_penalty up to 2 against repetition
6. Drop the context to 32,768 tokens if memory runs out, as the card suggests
7. Validate JSON yourself or use the runtime's guided decoding, since structured output isn't documented

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented