Qwen3.5-397B-A17B vs Qwen3.5-4B

Qwen3.5-397B-A17B

Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

Qwen3.5-4B

A small vision-language cousin for tool calls, light agent steps and image or video reading on almost any machine, with switchable thinking. Ollama's 3.3 GB build or the 9.3 GB BF16 files run in every major runtime under plain Apache 2.0. The main risks are no safety results, no structured-output guarantee and no answers from Alibaba since March.

Qwen3.5-397B-A17B

1. The card's server command is vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass "enable_thinking": false directly, while vLLM and SGLang take "chat_template_kwargs": {"enable_thinking": false}
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add --speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented

Qwen3.5-4B

1. Smallest start is ollama run qwen3.5:4b (Q4_K_M, about 4 GB with context)
2. Full precision vllm serve Qwen/Qwen3.5-4B --port 8000 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder
3. Turn thinking off with "chat_template_kwargs": {"enable_thinking": false} in the request body, since it's on by default and /think and /nothink aren't supported
4. There's no generation_config.json, so pass the card's sampling yourself, for example temperature=0.7, top_p=0.8, top_k=20, presence_penalty=1.5 without thinking
5. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
6. Validate any JSON it returns, since structured output isn't documented