Gemma 4 12B IT vs Qwen3.5-0.8B

Gemma 4 12B IT

A mid-size cousin for agent work with tools, optional thinking and image and audio input, under Apache 2.0. Google's 4-bit build needs under 9 GB with working space, so it runs on a 12 GB GPU or any recent Mac in all the common runtimes. The main risks are no published safety results and no documented JSON output.

Qwen3.5-0.8B

A tiny vision-language cousin for prototypes, fine-tuning and light local steps such as routing, tagging or reading an image, running in under 2 GB in every major runtime under plain Apache 2.0. Keep thinking off, since the card warns it loops. The main risk is neglect, with no hosted option, safety results or answers from Alibaba since March.

Gemma 4 12B IT

1. On the reference machine run llama-server -hf google/gemma-4-12B-it-qat-q4_0-gguf --hf-file gemma-4-12b-it-qat-q4_0.gguf --jinja -c 131072, and add --mmproj with mmproj-gemma-4-12b-it-qat-q4_0.gguf for images and audio
2. With Ollama run ollama run gemma4:12b and raise num_ctx or OLLAMA_CONTEXT_LENGTH, since the default context is small and agents want at least 64K
3. In vLLM or SGLang pass --tool-call-parser gemma4 --reasoning-parser gemma4 (vLLM also --enable-auto-tool-choice), or tool calls come back as text; Google's w4a16 build is the 4-bit route there
4. Thinking is off by default; pass enable_thinking=True or start the system prompt with <|think|>, and drop earlier turns' thinking from history except on tool-call turns
5. Put images before the text and audio after it, keep audio to 30 seconds and video to 60 frames, and validate tool names and arguments before running them
6. Transformers needs 5.10.0 or later for gemma4_unified, and mlx-lm has no gemma4_unified code, so on a Mac use mlx-vlm, LM Studio or Ollama

Qwen3.5-0.8B

1. Smallest start is ollama run qwen3.5:0.8b, or qwen3.5:0.8b-q8_0 at 1.0 GB
2. Full precision vllm serve Qwen/Qwen3.5-0.8B --port 8000 --max-model-len 262144 --enable-auto-tool-choice --tool-call-parser qwen3_coder
3. Thinking is off by default; if you turn it on with "chat_template_kwargs": {"enable_thinking": true}, stream and cut off runaway output, since the card warns of thinking loops, and add --reasoning-parser qwen3 in vLLM or SGLang to split the reasoning out
4. There's no generation_config.json, so pass the card's sampling yourself, for example temperature=1.0, top_p=1.0, top_k=20, presence_penalty=2.0 for text without thinking
5. Use it for narrow steps or as a fine-tuning base, not as the main agent, as the card itself suggests
6. Validate any JSON it returns, since structured output isn't documented