Head to head · Patient record retrieval · October 2026 research run
1upHealth vs Particle Health
Particle Health scores 48.6 (D) on agent readiness against 1upHealth's 46.8 (D), and leads in 3 of 7 scored categories. 1upHealth leads on security & auth, payments & pricing, maintenance & community and transparency & trust. Both do patient record retrieval.
Best health record and wellness data APIs for AI agents · All 63 health comparisons
Which one, for what
Best for Consumer and care apps that read a member's health plan claims and clinical data under the CMS rules, and payers meeting those rules.
Ahead on
- Security & auth, 63 against 57
- Payments & pricing, 20 against 5
- Maintenance & community, 37 against 27
- Transparency & trust, 72 against 48
Watch for
No rate limits, 429 handling or error formats documented
Best for US providers, payers and digital health companies that need a patient's network records as FHIR or flat data, and care-event alerts.
Ahead on
- Reliability, 58 against 52
- Schema & documentation, 69 against 50
- Agent ergonomics, 53 against 32
Watch for
Credentials come from a Particle representative, and the 'play for free' sign-up domain did not resolve
Score by category
| Category | Weight this run | 1upHealth | Particle Health | Edge |
|---|---|---|---|---|
| Reliability | 16%20 | 52 | 58 | Particle Health +6 |
| Performance | 10%pending | pending | pending | not scored in this run |
| Schema & documentation | 13%16.2 | 50 | 69 | Particle Health +19 |
| Agent ergonomics | 13%16.2 | 32 | 53 | Particle Health +21 |
| Security & auth | 14%17.5 | 63 | 57 | 1upHealth +6 |
| Payments & pricing | 10%12.5 | 20 | 5 | 1upHealth +15 |
| Task success | 10%pending | pending | pending | not scored in this run |
| Maintenance & community | 7%8.8 | 37 | 27 | 1upHealth +10 |
| Transparency & trust | 7%8.8 | 72 | 48 | 1upHealth +24 |
| Negative events | ≤15 | 0 | 0 | |
| Total | D 46.8/100 | D 48.6/100 |
Facts side by side
| Fact | 1upHealth | Particle Health |
|---|---|---|
| Kind | HTTP API | HTTP API |
| Vendor | 1upHealth, Inc. | Particle Health, Inc. |
| Hosted endpoint | no (local only) | no (local only) |
| Transports | HTTP | HTTP |
| Auth | OAuth | OAuth |
| Pricing | Paid | Paid |
| x402 | no | no |
| Licence | Proprietary service under 1upHealth's Terms of Service (effective 1 August 2024) | Proprietary service under customer agreements. The public terms of use (effective 15 October 2020) cover the website only |
| Read-only variant documented | no | no |
| llms.txt | yes | yes |
| Terms last updated | no date given | 2020-10-15 |
| Privacy policy last updated | 2026-06-25 | 2026-07-29 |
| Customer content may train models | not found in the text | not found in the text |
| Terms restrict automated access | not found in the text | yes |
| Terms restrict benchmarking | yes | not found in the text |
| Terms or service can change without notice | not found in the text | yes |
| Arbitration or class-action waiver | not found in the text | yes |
Verdicts
1upHealth
Self-serve Dev Portal sandbox clients and a demo health plan let an app test the CMS Patient Access, Provider Access and Payer-to-Payer FHIR APIs, backed by HITRUST and SOC 2 Type 2. No rate limits, error formats or dated releases are documented, and the Patient Access OAuth step needs the member in a browser.
Particle Health
Particle queries Carequality, CommonWell, eHealth Exchange and state HIEs for a patient and returns FHIR R4B, flat data or C-CDA, with project-scoped 60-minute tokens and OpenAPI fragments per endpoint. Credentials come through a representative, the free sign-up link was dead on 14 October 2026, and rate limits, SLA and changelog are unpublished.
Before you call either
1upHealth
- Hand the Patient Access sign-in to the member, who must authorise in the health plan's auth app
- Exchange the authorisation code within five minutes, and refresh before the 15-minute token expires
- Email payer-patient-access@1up.health with the client ID to get the app synced to the demo environment
- Expect only claims and coverage resources from some payers, and read /r4/metadata first
Particle Health
- Pass
projects/<project_id>as the scope when requesting a token, and request a new one every 60 minutes - Poll Get Query Status, or wait for the query-complete webhook, before reading FHIR or flat data
- Back off on 429, since limits change with system load
- Pass continuation tokens back verbatim when paging
- Use the published synthetic patients in sandbox, and stay under 500 queries a day
Questions
Which is better for AI agents, 1upHealth or Particle Health?
Particle Health scores 48.6 (D) on agent readiness against 1upHealth's 46.8 (D), and leads in 3 of 7 scored categories. 1upHealth leads on security & auth, payments & pricing, maintenance & community and transparency & trust.
Do 1upHealth and Particle Health need an API key?
Both use an OAuth sign-in.
Can an agent call 1upHealth and Particle Health without installing anything?
No hosted endpoint is listed for 1upHealth. No hosted endpoint is listed for Particle Health.
Other comparisons with 1upHealth or Particle Health
- 1upHealth vs ROOK
- 1upHealth vs Terra API
- Aidbox vs Particle Health
- Medplum vs Particle Health
- Particle Health vs ROOK
- Particle Health vs Terra API
- 1upHealth vs Aidbox
- 1upHealth vs Health Gorilla
- 1upHealth vs Medblocks
- 1upHealth vs Medplum
- 1upHealth vs Metriport Medical API
- 1upHealth vs Redox
- 1upHealth vs Zus Health
- Health Gorilla vs Particle Health
- Medblocks vs Particle Health
- Metriport Medical API vs Particle Health
- Particle Health vs Redox
- Particle Health vs Zus Health
- 1upHealth vs Validic Inform
Machine-readable
- This page as Markdown
/compare/1uphealth-vs-particle-health.md· slim.min.md· JSON.json(or sendAccept: text/markdown) - Each listing in full
/api/v1/tools/1uphealth.json·/api/v1/tools/particle-health.json - From a terminal
anchor compare 1uphealth particle-health(the CLI) - Over MCP
compare_tools {"a": "1uphealth", "b": "particle-health"}at/mcp, no key