Head to head · Patient record retrieval · October 2026 research run
1upHealth vs Aidbox
Aidbox scores 64.2 (B) on agent readiness against 1upHealth's 46.8 (D), and leads in 6 of 7 scored categories. 1upHealth leads on transparency & trust. Both do patient record retrieval.
Best health record and wellness data APIs for AI agents · All 63 health comparisons
Which one, for what
Best for Consumer and care apps that read a member's health plan claims and clinical data under the CMS rules, and payers meeting those rules.
Ahead on
- Transparency & trust, 72 against 45
Watch for
No rate limits, 429 handling or error formats documented
Aidbox B
Best for An organisation building its own clinical data repository, EHR or payer platform on FHIR, where an agent works against that store.
Ahead on
- Reliability, 59 against 52
- Schema & documentation, 77 against 50
- Agent ergonomics, 79 against 32
- Security & auth, 74 against 63
- Payments & pricing, 25 against 20
- Maintenance & community, 80 against 37
Watch for
No built-in rate limiting or brute-force protection, by the vendor's hardening page
Score by category
| Category | Weight this run | 1upHealth | Aidbox | Edge |
|---|---|---|---|---|
| Reliability | 16%20 | 52 | 59 | Aidbox +7 |
| Performance | 10%pending | pending | pending | not scored in this run |
| Schema & documentation | 13%16.2 | 50 | 77 | Aidbox +27 |
| Agent ergonomics | 13%16.2 | 32 | 79 | Aidbox +47 |
| Security & auth | 14%17.5 | 63 | 74 | Aidbox +11 |
| Payments & pricing | 10%12.5 | 20 | 25 | Aidbox +5 |
| Task success | 10%pending | pending | pending | not scored in this run |
| Maintenance & community | 7%8.8 | 37 | 80 | Aidbox +43 |
| Transparency & trust | 7%8.8 | 72 | 45 | 1upHealth +27 |
| Negative events | ≤15 | 0 | 0 | |
| Total | D 46.8/100 | B 64.2/100 |
Facts side by side
| Fact | 1upHealth | Aidbox |
|---|---|---|
| Kind | HTTP API | HTTP API |
| Vendor | 1upHealth, Inc. | Health Samurai, Inc. |
| Hosted endpoint | no (local only) | no (local only) |
| Transports | HTTP | HTTP, Streamable HTTP, SSE (legacy) |
| Auth | OAuth | OAuth |
| Pricing | Paid | Freemium |
| x402 | no | no |
| Licence | Proprietary service under 1upHealth's Terms of Service (effective 1 August 2024) | Proprietary. Aidbox runs from Health Samurai's Docker images under a free development licence (no PHI) or a paid production licence. Examples and the Python SDK on GitHub are MIT |
| Tools exposed | none | 9 |
| Read-only variant documented | no | no |
| llms.txt | yes | yes |
| Last release | none | 2026-10-08 |
| Terms last updated | no date given | no document linked |
| Privacy policy last updated | 2026-06-25 | 2021-06-10 |
| Customer content may train models | not found in the text | |
| Terms restrict automated access | not found in the text | |
| Terms restrict benchmarking | yes | |
| Terms or service can change without notice | not found in the text | |
| Arbitration or class-action waiver | not found in the text |
Verdicts
1upHealth
Self-serve Dev Portal sandbox clients and a demo health plan let an app test the CMS Patient Access, Provider Access and Payer-to-Payer FHIR APIs, backed by HITRUST and SOC 2 Type 2. No rate limits, error formats or dated releases are documented, and the Patient Access OAuth step needs the member in a browser.
Aidbox
Graded on the FHIR REST API of an Aidbox instance the owner runs. Monthly releases, two-year LTS lines, SMART on FHIR, AccessPolicy rules and AuditEvent logging are documented, and a free development licence needs no sales call. Aidbox has no rate limiting of its own, its MCP module is alpha, and no terms of service were found on the website.
Before you call either
1upHealth
- Hand the Patient Access sign-in to the member, who must authorise in the health plan's auth app
- Exchange the authorisation code within five minutes, and refresh before the 15-minute token expires
- Email payer-patient-access@1up.health with the client ID to get the app synced to the demo environment
- Expect only claims and coverage resources from some payers, and read /r4/metadata first
Aidbox
- Ask the operator for a Client with an AccessPolicy limited to the task. Don't rely on the public MCP policy, which the docs mark unsafe
- Use
If-None-Existon creates and conditional update on identifiers so retries don't duplicate records - Use
_elementsand_countto keep responses small, and follow the Bundle's paging links - Throttle yourself. Aidbox applies no rate limit, so a burst lands on the customer's database
- Don't load real patient data into an instance on a development licence
Questions
Which is better for AI agents, 1upHealth or Aidbox?
Aidbox scores 64.2 (B) on agent readiness against 1upHealth's 46.8 (D), and leads in 6 of 7 scored categories. 1upHealth leads on transparency & trust.
Do 1upHealth and Aidbox need an API key?
Both use an OAuth sign-in.
Can an agent call 1upHealth and Aidbox without installing anything?
No hosted endpoint is listed for 1upHealth. No hosted endpoint is listed for Aidbox.
Other comparisons with 1upHealth or Aidbox
- 1upHealth vs ROOK
- 1upHealth vs Terra API
- Aidbox vs Health Gorilla
- Aidbox vs Medblocks
- Aidbox vs Medplum
- Aidbox vs Metriport Medical API
- Aidbox vs Particle Health
- Aidbox vs Redox
- Aidbox vs ROOK
- Aidbox vs Terra API
- Aidbox vs Zus Health
- 1upHealth vs Health Gorilla
- 1upHealth vs Medblocks
- 1upHealth vs Medplum
- 1upHealth vs Metriport Medical API
- 1upHealth vs Particle Health
- 1upHealth vs Redox
- 1upHealth vs Zus Health
- 1upHealth vs Validic Inform
- Aidbox vs Validic Inform
Machine-readable
- This page as Markdown
/compare/1uphealth-vs-aidbox.md· slim.min.md· JSON.json(or sendAccept: text/markdown) - Each listing in full
/api/v1/tools/1uphealth.json·/api/v1/tools/aidbox.json - From a terminal
anchor compare 1uphealth aidbox(the CLI) - Over MCP
compare_tools {"a": "1uphealth", "b": "aidbox"}at/mcp, no key