Head to head · Patient record retrieval · October 2026 research run

1upHealth vs Metriport Medical API

Metriport Medical API scores 50.1 (D) on agent readiness against 1upHealth's 46.8 (D), and leads in 3 of 7 scored categories. 1upHealth leads on reliability, security & auth, payments & pricing and transparency & trust. Both do patient record retrieval.

Best health record and wellness data APIs for AI agents · All 63 health comparisons

Which one, for what

1upHealth D

Best for Consumer and care apps that read a member's health plan claims and clinical data under the CMS rules, and payers meeting those rules.

Ahead on

  • Reliability, 52 against 45
  • Security & auth, 63 against 41
  • Payments & pricing, 20 against 5
  • Transparency & trust, 72 against 56

Watch for

No rate limits, 429 handling or error formats documented

Metriport Medical API D

Best for US care providers and digital health companies that need a patient's network records as FHIR with webhooks.

Ahead on

  • Schema & documentation, 65 against 50
  • Agent ergonomics, 70 against 32
  • Maintenance & community, 74 against 37

Also in its favour

  • Open source

Watch for

Every API key has full access, including destructive operations, with no scopes

Score by category

CategoryWeight this run1upHealthMetriport Medical APIEdge
Reliability16%2052451upHealth +7
Performance10%pendingpendingpendingnot scored in this run
Schema & documentation13%16.25065Metriport Medical API +15
Agent ergonomics13%16.23270Metriport Medical API +38
Security & auth14%17.563411upHealth +22
Payments & pricing10%12.52051upHealth +15
Task success10%pendingpendingpendingnot scored in this run
Maintenance & community7%8.83774Metriport Medical API +37
Transparency & trust7%8.872561upHealth +16
Negative events≤1500
TotalD 46.8/100D 50.1/100

Facts side by side

Fact1upHealthMetriport Medical API
KindHTTP APIHTTP API
Vendor1upHealth, Inc.Metriport Inc.
Hosted endpointno (local only)no (local only)
TransportsHTTPHTTP
AuthOAuthAPI key
PricingPaidPaid
x402nono
LicenceProprietary service under 1upHealth's Terms of Service (effective 1 August 2024)Proprietary hosted service under Metriport's terms of use. The source in metriport/metriport is AGPLv3, with an enterprise directory under its own licence, and the @metriport/api-sdk package on npm is MIT
Read-only variant documentednono
llms.txtyesyes
Last releasenone2026-09-28
Terms last updatedno date given2024-01-01
Privacy policy last updated2026-06-252023-02-21
Customer content may train modelsnot found in the textnot found in the text
Terms restrict automated accessnot found in the textyes
Terms restrict benchmarkingyesyes
Terms or service can change without noticenot found in the textyes
Arbitration or class-action waivernot found in the textyes
Popularitynone793 stars, 28k npm/wk

Verdicts

1upHealth

Self-serve Dev Portal sandbox clients and a demo health plan let an app test the CMS Patient Access, Provider Access and Payer-to-Payer FHIR APIs, backed by HITRUST and SOC 2 Type 2. No rate limits, error formats or dated releases are documented, and the Patient Access OAuth step needs the member in a browser.

Metriport Medical API

One network query pulls a patient's records from HIEs, pharmacies and labs and returns deduplicated FHIR, with per-operation rate limits, RFC 7807 errors and AGPLv3 source. Each API key has full access with no scopes, there are no public prices, and the sandbox opens only after Metriport approves the account.

Before you call either

1upHealth

  1. Hand the Patient Access sign-in to the member, who must authorise in the health plan's auth app
  2. Exchange the authorisation code within five minutes, and refresh before the 15-minute token expires
  3. Email payer-patient-access@1up.health with the client ID to get the app synced to the demo environment
  4. Expect only claims and coverage resources from some payers, and read /r4/metadata first

Metriport Medical API

  1. Check the errors array after Start Network Query. It returns 2XX even when some sources fail
  2. Wait for network-query.* webhooks or poll Get Network Query Status before reading consolidated data, which is cached from the last query
  3. Send the resource's eTag in If-Match on updates to avoid overwriting newer data
  4. Keep patient creates under 15 a minute and network queries under 20 a minute per source
  5. In sandbox, create patients whose first name matches a pre-defined persona to get example records

Questions

Which is better for AI agents, 1upHealth or Metriport Medical API?

Metriport Medical API scores 50.1 (D) on agent readiness against 1upHealth's 46.8 (D), and leads in 3 of 7 scored categories. 1upHealth leads on reliability, security & auth, payments & pricing and transparency & trust.

Do 1upHealth and Metriport Medical API need an API key?

1upHealth uses an OAuth sign-in. Metriport Medical API needs an API key.

Can an agent call 1upHealth and Metriport Medical API without installing anything?

No hosted endpoint is listed for 1upHealth. No hosted endpoint is listed for Metriport Medical API.

Are 1upHealth and Metriport Medical API open source?

No open-source release is listed for 1upHealth. Metriport Medical API is open source (Proprietary hosted service under Metriport's terms of use. The source in metriport/metriport is AGPLv3, with an enterprise directory under its own licence, and the @metriport/api-sdk package on npm is MIT).

Other comparisons with 1upHealth or Metriport Medical API

Machine-readable

For companies

Do agents find, use and choose your tools?

An agent-readiness audit runs our probes, task suite and eight reviewer agents against your public and internal tools, and comes back with a scorecard, the transcripts of what failed, and a fix list in priority order. From $2,500, re-run included. We never take payment to move a rank. We do help companies earn one.