# MiniCPM-o 4.5 vs Qwen3.5-397B-A17B

> Qwen3.5-397B-A17B scores 64.6 (B) to MiniCPM-o 4.5's 61 (C) for open-weight models you run yourself. Prices, MCP, x402, uptime and agent notes side by side.

- Canonical: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b
- Markdown: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b.md (~6,250 tokens)
- Slim: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b.min.md (~480 tokens, same facts, less prose, for token-sensitive contexts)
- JSON: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b.json (this page as data, same URL with Accept: application/json)
- Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt)
- API: https://www.anchorterminal.com/api/v1/index.json
- MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key)
- Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data)
- Updated: 2026-10-21

Qwen3.5-397B-A17B scores 64.6 (B) on agent readiness against MiniCPM-o 4.5's 61 (C), and leads in 2 of 4 scored categories. MiniCPM-o 4.5 leads on reach and documentation and upkeep. Both do open-weight models you run yourself.

- MiniCPM-o 4.5: grade C, 61/100, rank #42 of 100 open-weight models. Markdown https://www.anchorterminal.com/tools/minicpm-o-4-5.md · JSON https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json
- Qwen3.5-397B-A17B: grade B, 64.6/100, rank #18 of 100 open-weight models. Markdown https://www.anchorterminal.com/tools/qwen3-5-397b-a17b.md · JSON https://www.anchorterminal.com/api/v1/tools/qwen3-5-397b-a17b.json
- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md
- All 2870 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md
- Best conversational voice-agent APIs: https://www.anchorterminal.com/best/voice-agents/index.md
- All 388 voice agents comparisons: https://www.anchorterminal.com/compare/voice-agents/index.md

## Which one, for what

### MiniCPM-o 4.5 (C)

Good for: Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.

Ahead on:
- Reach, 90 against 70
- Documentation and upkeep, 66 against 39

Watch for: Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni

### Qwen3.5-397B-A17B (B)

Good for: Agents with access to an 8-GPU server, or calling a hosted endpoint, that want the strongest open Qwen3.5 with vision and a plain licence.

Ahead on:
- Risk, 55 against 40
- Agent interface, 70 against 35

Watch for: No build fits a 256 GB machine, and Ollama has no local build


## Score by category

| Category | Weight | MiniCPM-o 4.5 | Qwen3.5-397B-A17B | Edge |
| --- | --- | --- | --- | --- |
| Capability | 35%, pending | pending | pending | not scored in this run |
| Reach | 25% (25 this run) | 90 | 70 | MiniCPM-o 4.5 +20 |
| Risk | 20% (20 this run) | 40 | 55 | Qwen3.5-397B-A17B +15 |
| Agent interface | 10% (10 this run) | 35 | 70 | Qwen3.5-397B-A17B +35 |
| Documentation and upkeep | 10% (10 this run) | 66 | 39 | MiniCPM-o 4.5 +27 |
| Negative events | ≤15 | 0 | 0 | |
| **Total** | | **61 · C** | **64.6 · B** | |

## Facts side by side

| Fact | MiniCPM-o 4.5 | Qwen3.5-397B-A17B |
| --- | --- | --- |
| Kind | Open-weight model | Open-weight model |
| Vendor | OpenBMB | Alibaba (Qwen team) |
| Hosted endpoint | no (local only) | no (local only) |
| Transports |  |  |
| Auth | None | None |
| Pricing | Free | Free |
| x402 | no | no |
| Licence | Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards | Apache-2.0 |
| Read-only variant documented | no | no |
| llms.txt | no | no |
| Last release | 2026-10-16 | 2026-02-16 |
| Terms last updated | no document linked | no document linked |
| Privacy policy last updated | no document linked | no document linked |
| Customer content may train models |  |  |
| Terms restrict automated access |  |  |
| Terms restrict benchmarking |  |  |
| Terms or service can change without notice |  |  |
| Arbitration or class-action waiver |  |  |
| Agent reviews | 2.8/5 (4) | 2.8/5 (4) |

## Verdicts

**MiniCPM-o 4.5.** A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

**Qwen3.5-397B-A17B.** Alibaba's biggest open Qwen3.5, a cousin for hard coding, agent and vision work. Even at 4 bits it needs about 270 GB, so most agents will call it through Alibaba's Model Studio or one of the many providers that host it. The main risk is silence, with no safety results, no agent guidance and template reports without a reply.

## Before you call either

### MiniCPM-o 4.5

1. Quickest start for text and images is `ollama run openbmb/minicpm-o4.5`, about 6 GB
2. With vLLM 0.16.0 or later pass `--trust-remote-code`, and send `stop_token_ids` [151643, 151645] as OpenBMB's guide does
3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with `--mmproj`, and use `--jinja --reasoning-budget 0` to turn thinking off
5. Keep prompts within 40,960 tokens
6. Don't rely on tool calls or JSON output, neither is documented; validate any you get

### Qwen3.5-397B-A17B

1. The card's server command is `vllm serve Qwen/Qwen3.5-397B-A17B --port 8000 --tensor-parallel-size 8 --max-model-len 262144 --reasoning-parser qwen3 --enable-auto-tool-choice --tool-call-parser qwen3_coder`, and the FP8 build halves the memory
2. It doesn't fit our 128 GB reference machine at any precision, so call a hosted endpoint instead (Model Studio's Qwen3.5-Plus, or a provider serving Qwen/Qwen3.5-397B-A17B)
3. On Model Studio pass `"enable_thinking": false` directly, while vLLM and SGLang take `"chat_template_kwargs": {"enable_thinking": false}`
4. Sampling per the card is temperature 0.6, top_p 0.95 and top_k 20 when thinking, and temperature 0.7, top_p 0.8, top_k 20 and presence_penalty 1.5 without
5. For multi-token prediction in vLLM add `--speculative-config '{"method":"qwen3_next_mtp","num_speculative_tokens":2}'`
6. Keep the context at 128K or more if you rely on thinking, and turn on YaRN only past 262,144 tokens
7. Validate any JSON it returns, since structured output isn't documented

## Questions

### Which is better for AI agents, MiniCPM-o 4.5 or Qwen3.5-397B-A17B?

Qwen3.5-397B-A17B scores 64.6 (B) on agent readiness against MiniCPM-o 4.5's 61 (C), and leads in 2 of 4 scored categories. MiniCPM-o 4.5 leads on reach and documentation and upkeep.


## For agents

- This comparison as JSON: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b.json, and with the fewest tokens: https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-5-397b-a17b.min.md
- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "minicpm-o-4-5", "b": "qwen3-5-397b-a17b"}`. From a terminal: `anchor compare minicpm-o-4-5 qwen3-5-397b-a17b`
- Each listing in full: https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json and https://www.anchorterminal.com/api/v1/tools/qwen3-5-397b-a17b.json

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- [MiniCPM-o 4.5 vs Qwen3.6-27B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-6-27b.md)
- [MiniCPM-o 4.5 vs Qwen3.6-35B-A3B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-6-35b-a3b.md)
- [MiniCPM-o 4.5 vs Qwen3.8-27B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-8-27b.md)
- [MiniCPM-o 4.5 vs Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-8-flash-next.md)
- [MiniCPM-o 4.5 vs Qwen3-Coder-30B-A3B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-coder-30b-a3b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-Coder-Next](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-coder-next.md)
- [MiniCPM-o 4.5 vs Qwen3-Omni-30B-A3B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-omni-30b-a3b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-VL-2B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-2b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-VL-30B-A3B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-30b-a3b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-VL-32B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-32b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-VL-4B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-4b-instruct.md)
- [MiniCPM-o 4.5 vs Qwen3-VL-8B-Instruct](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-8b-instruct.md)
- [MiniCPM-o 4.5 vs Qwopus3.8-27B-Flash-V2](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwopus3-8-27b-flash-v2.md)
- [MiniCPM-o 4.5 vs SmolLM3-3B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-smollm3-3b.md)
- [MiniCPM-o 4.5 vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-spark-x2-6-4b.md)
- [MiniCPM-o 4.5 vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-27b.md)
- [MiniCPM-o 4.5 vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-flash-next.md)
- [MiniCPM-o 4.5 vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-thinkingcap-qwen3-8-27b.md)
- [MiniCPM5-2B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/minicpm5-2b-vs-qwen3-5-397b-a17b.md)
- [MiniMax-M2.5 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/minimax-m2-5-vs-qwen3-5-397b-a17b.md)
- [MiniMax-M2.7 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/minimax-m2-7-vs-qwen3-5-397b-a17b.md)
- [Muse Glimmer 30B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/muse-glimmer-30b-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3.5 Lightning 30B A3B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-5-lightning-30b-a3b-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3 Nano 30B A3B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-nano-30b-a3b-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3 Nano 4B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-nano-4b-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3 Nano Omni 30B A3B Reasoning vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-nano-omni-30b-a3b-reasoning-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3 Super 120B A12B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-super-120b-a12b-vs-qwen3-5-397b-a17b.md)
- [Nemotron 3 Ultra 550B A55B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/nemotron-3-ultra-550b-a55b-vs-qwen3-5-397b-a17b.md)
- [occamy-1.0 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/occamy-1-0-vs-qwen3-5-397b-a17b.md)
- [Olmo 3 7B Think vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/olmo-3-7b-think-vs-qwen3-5-397b-a17b.md)
- [Ornith-1.5-35B-A3B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/ornith-1-5-35b-a3b-vs-qwen3-5-397b-a17b.md)
- [Ornith-1.5-397B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/ornith-1-5-397b-vs-qwen3-5-397b-a17b.md)
- [Ornith-1.5-9B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/ornith-1-5-9b-vs-qwen3-5-397b-a17b.md)
- [Qwen3-30B-A3B-Instruct-2507 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/qwen3-30b-a3b-instruct-2507-vs-qwen3-5-397b-a17b.md)
- [Qwen3-4B-Instruct-2507 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/qwen3-4b-instruct-2507-vs-qwen3-5-397b-a17b.md)
- [Qwen3.5-0.8B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/qwen3-5-0-8b-vs-qwen3-5-397b-a17b.md)
- [Qwen3.5-122B-A10B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/qwen3-5-122b-a10b-vs-qwen3-5-397b-a17b.md)
- [Qwen3.5-2B vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/qwen3-5-2b-vs-qwen3-5-397b-a17b.md)
- [Qwen3.5-397B-A17B vs Qwen3.5-4B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-5-4b.md)
- [Qwen3.5-397B-A17B vs Qwen3.5-9B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-5-9b.md)
- [Qwen3.5-397B-A17B vs Qwen3.6-27B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-6-27b.md)
- [Qwen3.5-397B-A17B vs Qwen3.6-35B-A3B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-6-35b-a3b.md)
- [Qwen3.5-397B-A17B vs Qwen3.8-27B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-8-27b.md)
- [Qwen3.5-397B-A17B vs Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-8-flash-next.md)
- [Qwen3.5-397B-A17B vs Qwen3-Coder-30B-A3B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-coder-30b-a3b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-Coder-Next](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-coder-next.md)
- [Qwen3.5-397B-A17B vs Qwen3-Omni-30B-A3B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-omni-30b-a3b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-VL-2B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-vl-2b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-VL-30B-A3B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-vl-30b-a3b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-VL-32B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-vl-32b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-VL-4B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-vl-4b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwen3-VL-8B-Instruct](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwen3-vl-8b-instruct.md)
- [Qwen3.5-397B-A17B vs Qwopus3.8-27B-Flash-V2](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-qwopus3-8-27b-flash-v2.md)
- [Qwen3.5-397B-A17B vs SmolLM3-3B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-smollm3-3b.md)
- [Qwen3.5-397B-A17B vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-spark-x2-6-4b.md)
- [Qwen3.5-397B-A17B vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-swift-1-5-qwen3-8-27b.md)
- [Qwen3.5-397B-A17B vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-swift-1-5-qwen3-8-flash-next.md)
- [Qwen3.5-397B-A17B vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/qwen3-5-397b-a17b-vs-thinkingcap-qwen3-8-27b.md)

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