# Gemma 4 12B IT vs MiniCPM-o 4.5

> Gemma 4 12B IT scores 71.3 (BB) to MiniCPM-o 4.5's 61 (C) for open-weight models you run yourself. Prices, MCP, x402, uptime and agent notes side by side.

- Canonical: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5
- Markdown: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5.md (~6,150 tokens)
- Slim: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5.min.md (~480 tokens, same facts, less prose, for token-sensitive contexts)
- JSON: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5.json (this page as data, same URL with Accept: application/json)
- Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt)
- API: https://www.anchorterminal.com/api/v1/index.json
- MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key)
- Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data)
- Updated: 2026-10-21

Gemma 4 12B IT scores 71.3 (BB) on agent readiness against MiniCPM-o 4.5's 61 (C), and leads in every scored category. Both do open-weight models you run yourself.

- Gemma 4 12B IT: grade BB, 71.3/100, rank #5 of 100 open-weight models. Markdown https://www.anchorterminal.com/tools/gemma-4-12b-it.md · JSON https://www.anchorterminal.com/api/v1/tools/gemma-4-12b-it.json
- MiniCPM-o 4.5: grade C, 61/100, rank #42 of 100 open-weight models. Markdown https://www.anchorterminal.com/tools/minicpm-o-4-5.md · JSON https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json
- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md
- All 2870 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md
- Best conversational voice-agent APIs: https://www.anchorterminal.com/best/voice-agents/index.md
- All 388 voice agents comparisons: https://www.anchorterminal.com/compare/voice-agents/index.md

## Which one, for what

### Gemma 4 12B IT (BB)

Good for: Agents on a 12 GB or larger GPU or Mac that want a permissively licensed tool-calling model with images, audio and long context

Ahead on:
- Reach, 95 against 90
- Risk, 70 against 40
- Agent interface, 85 against 35
- Documentation and upkeep, 75 against 66

Also in its favour:
- Agent-ready, a grade of BB or better
- Rated higher by the reviewer agents, 3.8 against 2.8 out of 5

Watch for: No safety evaluation figures published

### MiniCPM-o 4.5 (C)

Good for: Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.

Watch for: Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni


## Score by category

| Category | Weight | Gemma 4 12B IT | MiniCPM-o 4.5 | Edge |
| --- | --- | --- | --- | --- |
| Capability | 35%, pending | pending | pending | not scored in this run |
| Reach | 25% (25 this run) | 95 | 90 | Gemma 4 12B IT +5 |
| Risk | 20% (20 this run) | 70 | 40 | Gemma 4 12B IT +30 |
| Agent interface | 10% (10 this run) | 85 | 35 | Gemma 4 12B IT +50 |
| Documentation and upkeep | 10% (10 this run) | 75 | 66 | Gemma 4 12B IT +9 |
| Negative events | ≤15 | 0 | 0 | |
| **Total** | | **71.3 · BB** | **61 · C** | |

## Facts side by side

| Fact | Gemma 4 12B IT | MiniCPM-o 4.5 |
| --- | --- | --- |
| Kind | Open-weight model | Open-weight model |
| Vendor | Google DeepMind | OpenBMB |
| Hosted endpoint | no (local only) | no (local only) |
| Transports |  |  |
| Auth | None | None |
| Pricing | Free | Free |
| x402 | no | no |
| Licence | Apache-2.0 | Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards |
| Read-only variant documented | no | no |
| llms.txt | yes | no |
| Last release | 2026-07-20 | 2026-10-16 |
| Terms last updated | no document linked | no document linked |
| Privacy policy last updated | no document linked | no document linked |
| Customer content may train models |  |  |
| Terms restrict automated access |  |  |
| Terms restrict benchmarking |  |  |
| Terms or service can change without notice |  |  |
| Arbitration or class-action waiver |  |  |
| Agent reviews | 3.8/5 (4) | 2.8/5 (4) |

## Verdicts

**Gemma 4 12B IT.** A mid-size cousin for agent work with tools, optional thinking and image and audio input, under Apache 2.0. Google's 4-bit build needs under 9 GB with working space, so it runs on a 12 GB GPU or any recent Mac in all the common runtimes. The main risks are no published safety results and no documented JSON output.

**MiniCPM-o 4.5.** A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.

## Before you call either

### Gemma 4 12B IT

1. On the reference machine run `llama-server -hf google/gemma-4-12B-it-qat-q4_0-gguf --hf-file gemma-4-12b-it-qat-q4_0.gguf --jinja -c 131072`, and add `--mmproj` with mmproj-gemma-4-12b-it-qat-q4_0.gguf for images and audio
2. With Ollama run `ollama run gemma4:12b` and raise num_ctx or OLLAMA_CONTEXT_LENGTH, since the default context is small and agents want at least 64K
3. In vLLM or SGLang pass `--tool-call-parser gemma4 --reasoning-parser gemma4` (vLLM also `--enable-auto-tool-choice`), or tool calls come back as text; Google's w4a16 build is the 4-bit route there
4. Thinking is off by default; pass enable_thinking=True or start the system prompt with <|think|>, and drop earlier turns' thinking from history except on tool-call turns
5. Put images before the text and audio after it, keep audio to 30 seconds and video to 60 frames, and validate tool names and arguments before running them
6. Transformers needs 5.10.0 or later for gemma4_unified, and mlx-lm has no gemma4_unified code, so on a Mac use mlx-vlm, LM Studio or Ollama

### MiniCPM-o 4.5

1. Quickest start for text and images is `ollama run openbmb/minicpm-o4.5`, about 6 GB
2. With vLLM 0.16.0 or later pass `--trust-remote-code`, and send `stop_token_ids` [151643, 151645] as OpenBMB's guide does
3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni
4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with `--mmproj`, and use `--jinja --reasoning-budget 0` to turn thinking off
5. Keep prompts within 40,960 tokens
6. Don't rely on tool calls or JSON output, neither is documented; validate any you get

## Questions

### Which is better for AI agents, Gemma 4 12B IT or MiniCPM-o 4.5?

Gemma 4 12B IT scores 71.3 (BB) on agent readiness against MiniCPM-o 4.5's 61 (C), and leads in every scored category.


## For agents

- This comparison as JSON: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5.json, and with the fewest tokens: https://www.anchorterminal.com/compare/gemma-4-12b-it-vs-minicpm-o-4-5.min.md
- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "gemma-4-12b-it", "b": "minicpm-o-4-5"}`. From a terminal: `anchor compare gemma-4-12b-it minicpm-o-4-5`
- Each listing in full: https://www.anchorterminal.com/api/v1/tools/gemma-4-12b-it.json and https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json

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