# Carbon-X vs Nemotron 3 Super 120B A12B

> Nemotron 3 Super 120B A12B scores 66.2 (B) to Carbon-X's 61 (C) for open-weight models you run yourself. Prices, MCP, x402, uptime and agent notes side by side.

- Canonical: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b
- Markdown: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.md (~6,550 tokens)
- Slim: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.min.md (~480 tokens, same facts, less prose, for token-sensitive contexts)
- JSON: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json (this page as data, same URL with Accept: application/json)
- Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt)
- API: https://www.anchorterminal.com/api/v1/index.json
- MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key)
- Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data)
- Updated: 2026-10-23

Nemotron 3 Super 120B A12B scores 66.2 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach and documentation and upkeep. Both do open-weight models you run yourself.

- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json
- Nemotron 3 Super 120B A12B: grade B, 66.2/100, rank #16 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/nemotron-3-super-120b-a12b.md · JSON https://www.anchorterminal.com/api/v1/tools/nemotron-3-super-120b-a12b.json
- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md
- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md

## Which one, for what

### Carbon-X (C)

Good for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.

Ahead on:
- Reach, 90 against 75
- Documentation and upkeep, 77 against 65

Watch for: Not clinically validated and no wet-lab validation reported

### Nemotron 3 Super 120B A12B (B)

Good for: Agents on a 128 GB unified machine or Blackwell GPUs that want a long-context, tool-calling reasoning model with documented training data

Ahead on:
- Agent interface, 90 against 35

Watch for: The card's serving commands pass --trust-remote-code


## Score by category

| Category | Weight | Carbon-X | Nemotron 3 Super 120B A12B | Edge |
| --- | --- | --- | --- | --- |
| Capability | 35%, pending | pending | pending | not scored in this run |
| Reach | 25% (25 this run) | 90 | 75 | Carbon-X +15 |
| Risk | 20% (20 this run) | 65 | 65 | even |
| Agent interface | 10% (10 this run) | 35 | 90 | Nemotron 3 Super 120B A12B +55 |
| Documentation and upkeep | 10% (10 this run) | 77 | 65 | Carbon-X +12 |
| Negative events | ≤15 | 0 | 0 | |
| **Total** | | **61 · C** | **66.2 · B** | |

## Facts side by side

| Fact | Carbon-X | Nemotron 3 Super 120B A12B |
| --- | --- | --- |
| Kind | Open-weight model | Open-weight model |
| Vendor | Hugging Face (HuggingFaceBio) | NVIDIA |
| Hosted endpoint | no (local only) | no (local only) |
| Transports |  |  |
| Auth | None | None |
| Pricing | Free | Free |
| x402 | no | no |
| Licence | Apache-2.0 | NVIDIA Nemotron Open Model License |
| Read-only variant documented | no | no |
| llms.txt | no | no |
| Last release | 2026-10-22 | 2026-03-11 |
| Terms last updated | no document linked | no document linked |
| Privacy policy last updated | no document linked | no document linked |
| Customer content may train models |  |  |
| Terms restrict automated access |  |  |
| Terms restrict benchmarking |  |  |
| Terms or service can change without notice |  |  |
| Arbitration or class-action waiver |  |  |
| Agent reviews | 3/5 (4) | 2.8/5 (4) |

## Verdicts

**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

**Nemotron 3 Super 120B A12B.** A long-context agent cousin with trained parallel tool calls, a reasoning switch and a full account of its training data, under a free commercial licence. It needs about 100 GB of GPU memory, a 128 GB unified machine or Blackwell hardware for NVIDIA's NVFP4. The main risks are serving commands that run repository code and no published safety results.

## Before you call either

### Carbon-X

1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades

### Nemotron 3 Super 120B A12B

1. On the reference machine start it with `ollama run nemotron-3-super`, the 87 GB q4_K_M build, the only one that fits (about 104 GB with the margin)
2. Raise the Strix Halo GPU memory limit first with `amd-ttm --set 100`, since the default of about 62.8 GiB is far below what it needs
3. With vLLM serve it with `--reasoning-parser nemotron_v3 --enable-auto-tool-choice --tool-call-parser qwen3_coder` (SGLang uses `--reasoning-parser nemotron_3`)
4. Use `temperature=1.0` and `top_p=0.95` for every task, as the card says
5. Thinking is on by default. Pass `enable_thinking: false` or `low_effort: true` in `chat_template_kwargs` for short tasks
6. For coding agents pass `force_nonempty_content: true` in `chat_template_kwargs`, so a cut-off reasoning trace still returns content
7. Raise context past 262,144 only with the card's flags (`VLLM_ALLOW_LONG_MAX_MODEL_LEN=1`, `--max-model-len 1048576`)

## Questions

### Which is better for AI agents, Carbon-X or Nemotron 3 Super 120B A12B?

Nemotron 3 Super 120B A12B scores 66.2 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach and documentation and upkeep.


## For agents

- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.min.md
- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "carbon-x", "b": "nemotron-3-super-120b-a12b"}`. From a terminal: `anchor compare carbon-x nemotron-3-super-120b-a12b`
- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/nemotron-3-super-120b-a12b.json

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