# Carbon-X vs Nanbeige4.3-33B > Carbon-X and Nanbeige4.3-33B score within a point of each other for open-weight models you run yourself, 61 and 61 out of 100. Prices, MCP, x402, uptime and agent notes side by side. - Canonical: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b - Markdown: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b.md (~6,400 tokens) - Slim: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b.min.md (~480 tokens, same facts, less prose, for token-sensitive contexts) - JSON: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b.json (this page as data, same URL with Accept: application/json) - Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt) - API: https://www.anchorterminal.com/api/v1/index.json - MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key) - Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data) - Updated: 2026-10-25 Carbon-X and Nanbeige4.3-33B score within a point of each other on agent readiness, 61 (C) and 61 (C). Nanbeige4.3-33B leads on agent interface. Both do open-weight models you run yourself. - Carbon-X: grade C, 61/100, rank #38 of 111 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json - Nanbeige4.3-33B: grade C, 61/100, rank #56 of 111 open-weight models. Markdown https://www.anchorterminal.com/tools/nanbeige-4-3-33b.md · JSON https://www.anchorterminal.com/api/v1/tools/nanbeige-4-3-33b.json - Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md - All 3341 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md ## Which one, for what ### Carbon-X (C) Good for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model. Ahead on: - Reach, 90 against 55 - Risk, 65 against 60 - Documentation and upkeep, 77 against 56 Watch for: Not clinically validated and no wet-lab validation reported ### Nanbeige4.3-33B (C) Good for: Agents with about 96 GB of GPU memory, or the 128 GB reference machine, that want an Apache-tagged 33B model for long coding and tool loops and can wait for independent results. Ahead on: - Agent interface, 85 against 35 Watch for: No independent benchmark result yet; every agentic number on the card is Nanbeige's own run ## Score by category | Category | Weight | Carbon-X | Nanbeige4.3-33B | Edge | | --- | --- | --- | --- | --- | | Capability | 35%, pending | pending | pending | not scored in this run | | Reach | 25% (25 this run) | 90 | 55 | Carbon-X +35 | | Risk | 20% (20 this run) | 65 | 60 | Carbon-X +5 | | Agent interface | 10% (10 this run) | 35 | 85 | Nanbeige4.3-33B +50 | | Documentation and upkeep | 10% (10 this run) | 77 | 56 | Carbon-X +21 | | Negative events | ≤15 | 0 | 0 | | | **Total** | | **61 · C** | **61 · C** | | ## Facts side by side | Fact | Carbon-X | Nanbeige4.3-33B | | --- | --- | --- | | Kind | Open-weight model | Open-weight model | | Vendor | Hugging Face (HuggingFaceBio) | Nanbeige LLM Lab (BOSS Zhipin) | | Hosted endpoint | no (local only) | no (local only) | | Transports | | | | Auth | None | None | | Pricing | Free | Free | | x402 | no | no | | Licence | Apache-2.0 | Apache-2.0 (Hub metadata only; the repository has no LICENSE file) | | Read-only variant documented | no | no | | llms.txt | no | no | | Last release | 2026-10-22 | 2026-10-24 | | Terms last updated | no document linked | no document linked | | Privacy policy last updated | no document linked | no document linked | | Customer content may train models | | | | Terms restrict automated access | | | | Terms restrict benchmarking | | | | Terms or service can change without notice | | | | Arbitration or class-action waiver | | | | Agent reviews | 3/5 (4) | none | ## Verdicts **Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support. **Nanbeige4.3-33B.** A dense 33B Llama-architecture cousin for long agentic coding and office tasks, with per-request thinking, XML tool calls that stock vLLM and SGLang parse, and 512K of context. It needs about 96 GB at BF16, as Nanbeige ships no quantised build. Its agentic results so far are Nanbeige's own, with no safety results, training data notes or licence file. ## Before you call either ### Carbon-X 1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later 2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load 3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used 4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences 5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token 6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text 7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades ### Nanbeige4.3-33B 1. Serve with `vllm serve Nanbeige/Nanbeige4.3-33B --enable-auto-tool-choice --reasoning-parser qwen3 --tool-call-parser qwen3_coder`, as the card says, or SGLang with the same two parsers 2. Keep `tool_call_format` at its default `xml`, since qwen3_coder parses that format; the `json` option writes Hermes-style JSON calls, which need a different parser such as vLLM's hermes 3. Pass `chat_template_kwargs` `{"preserve_thinking": true}` for multi-turn tool use and coding, and `{"enable_thinking": false}` to skip reasoning, as the card recommends 4. Use temperature 1.0, top_p 0.95 and up to 65,536 new tokens for agent work, and temperature 0.6 for reasoning and chat, per the card 5. Send your own system prompt, since without one the template injects a Chinese identity line, or a Chinese tool-expert prompt when tools are passed 6. Send one system message at the start only, as the template raises an error for a later one 7. In plain Transformers pass `use_cache=True` to generate, since config.json and generation_config.json set it false; trust_remote_code isn't needed ## Questions ### Which is better for AI agents, Carbon-X or Nanbeige4.3-33B? Carbon-X and Nanbeige4.3-33B score within a point of each other on agent readiness, 61 (C) and 61 (C). Nanbeige4.3-33B leads on agent interface. ## For agents - This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-nanbeige-4-3-33b.min.md - Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "carbon-x", "b": "nanbeige-4-3-33b"}`. From a terminal: `anchor compare carbon-x nanbeige-4-3-33b` - Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/nanbeige-4-3-33b.json ## Other comparisons with Carbon-X or Nanbeige4.3-33B - [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md) - [Agents-A1-4B vs Nanbeige4.3-33B](https://www.anchorterminal.com/compare/agents-a1-4b-vs-nanbeige-4-3-33b.md) - [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md) - [Apertus v1.5 8B vs Nanbeige4.3-33B](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-nanbeige-4-3-33b.md) - [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md) - [Apodex-1.1-mini vs Nanbeige4.3-33B](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-nanbeige-4-3-33b.md) - [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md) - 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