{ "data": { "a": { "slug": "carbon-x", "name": "Carbon-X", "vendor": "Hugging Face (HuggingFaceBio)", "vendorUrl": "https://huggingface.co/HuggingFaceBio", "kind": "weights", "category": "open-weights", "summary": "Carbon-X is Hugging Face's open-weight 14.8B language model for DNA, a fine-tune of Qwen3-14B that reads raw DNA in a chat and answers in English about variant effects and regulatory regions, with a 40,960-token context, under Apache 2.0.", "url": "https://www.anchorterminal.com/tools/carbon-x", "markdownUrl": "https://www.anchorterminal.com/tools/carbon-x.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/carbon-x.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/carbon-x.json", "repo": "https://huggingface.co/HuggingFaceBio/Carbon-X", "license": "Apache-2.0", "transports": [], "packages": [ { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X" }, { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X-GGUF" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The Hub reports gated false for HuggingFaceBio/Carbon-X and HuggingFaceBio/Carbon-X-GGUF (checked 2026-10-23). The Python tokenizer fetches Qwen/Qwen3-4B-Base's tokenizer at a pinned revision on first load, which is also ungated.", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0, and the base Qwen3-14B is Apache 2.0 too. Hugging Face sells no per-call access to it and no inference provider serves it. Running it costs the hardware, 29.6 GB for the BF16 safetensors and 9.6 GB for the publisher's smallest GGUF, Q4_K_M (checked 2026-10-23).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-23).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-23" }, "docsUrl": "https://huggingface.co/HuggingFaceBio/Carbon-X", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "dense", "dna", "genomics", "biology", "fine-tune", "apache-2.0", "safetensors", "gguf", "self-hosted" ], "lastRelease": "2026-10-22", "graded": true, "anchor": { "graded": true, "score": 61, "grade": "C", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 30, "methodology": "0.6", "run": "2026-10-01", "scores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "low", "date": "2026-10-23" }, "negative": 0, "verdict": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "bestFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "strengths": [ "Hugging Face's own GGUFs at four precisions, the smallest about 12 GB with a fifth added", "Runs in released llama.cpp, vLLM, SGLang and Transformers", "Apache 2.0 on the model and its Qwen3-14B base, nothing gated", "A ready-made skill, an OpenAI-style tool example and an Inspect example for calling it from another agent", "Mid-training data listed by source with shares of 302B tokens" ], "weaknesses": [ "Not clinically validated and no wet-lab validation reported", "The Python tokenizer needs trust_remote_code, and llama.cpp before b11742 tokenizes DNA wrongly", "Not trained for tool calling, structured output or reasoning", "The card says llama.cpp is unsupported while the publisher's GGUF repository says it is", "No inference provider or hosted API, and no knowledge cut-off" ], "agentNotes": [ "Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later", "With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load", "Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used", "Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences", "Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token", "Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text", "Cap max_tokens for next-base questions, long DNA generation is slow and degrades" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 3, "history": [ { "basis": "public evidence", "confidence": "low", "grade": "C", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 61 } ], "editorialScores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "provenanceScore": 53, "checked": { "categories": { "interface": "2026-10-23", "reach": "2026-10-23", "risk": "2026-10-23", "upkeep": "2026-10-23" }, "last": "2026-10-23", "oldest": "2026-10-23", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "# llama.cpp b11742 or later (older builds tokenize DNA wrongly):\nllama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja \\\n --chat-template-kwargs '{\"enable_thinking\": false}' \\\n --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080\n# or, with vLLM:\nvllm serve HuggingFaceBio/Carbon-X --trust-remote-code", "http": "curl http://localhost:8080/v1/chat/completions -H 'Content-Type: application/json' \\\n -d '{\"messages\": [{\"role\": \"user\", \"content\": \"Is this sequence more likely coding or non-coding? ATGGCGCTGTGGATGCGCCTCCTG\"}]}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/carbon-x" }, "sameCompany": [ "hugging-face-inference-endpoints", "smollm3-3b" ], "weights": { "trainedBy": "Hugging Face with Zhongguancun Academy and TIGEM / University of Naples Federico II", "builtOn": "Qwen/Qwen3-14B (vocabulary extension, mid-training, supervised fine-tune and GRPO; base Apache 2.0, declared in the card's metadata)", "params": "14.8B", "context": 40960, "goodFor": "A DNA specialist another agent calls, for variant-effect questions, regulatory regions and next-base prediction on raw DNA kept on local hardware.", "runtimes": [ "llama.cpp", "vLLM", "SGLang", "Transformers" ], "builds": [ { "name": "Carbon-X-GGUF Q4_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q4_k_m", "sizeGB": 9.64, "memoryGB": 12, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q4_k_m.gguf, 9,636,318,080 bytes. Embedding and output tensors stay at Q8_0. The publisher's own runs put it lowest of the builds on FrontierVEP (67.8) and NextBase (38.6)" }, { "name": "Carbon-X-GGUF Q6_K", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q6_k", "sizeGB": 12.56, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q6_k.gguf, 12,555,946,880 bytes" }, { "name": "Carbon-X-GGUF Q5_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q5_k_m", "sizeGB": 11.05, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q5_k_m.gguf, 11,051,895,680 bytes" }, { "name": "Carbon-X-GGUF Q8_0", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q8_0", "sizeGB": 15.76, "memoryGB": 24, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q8_0.gguf, 15,755,742,080 bytes, the build the publisher recommends" }, { "name": "Carbon-X", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X", "who": "publisher", "precision": "bf16", "sizeGB": 29.64, "memoryGB": 48, "format": "safetensors", "runsOn": [ "vLLM", "Transformers" ], "note": "Needs trust_remote_code for the custom HybridDNATokenizer, and Transformers v5 or later. The card says it fits one 80 GB GPU" }, { "name": "Carbon-X-GGUF BF16", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "bf16", "sizeGB": 29.65, "memoryGB": 48, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-bf16.gguf, 29,651,012,480 bytes. llama.cpp b11742 or later" } ], "run": "llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080", "runBuild": "Carbon-X-GGUF Q8_0", "checked": "2026-10-23", "minMemoryGB": 12 }, "family": { "lab": "Hugging Face (Carbon)", "family": "Carbon", "url": "https://www.anchorterminal.com/open-weights/#huggingface-bio", "others": [ { "name": "Carbon-A-1.2B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-A-1.2B", "params": "1.2B" }, { "name": "Carbon-8B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-8B", "params": "8.3B" }, { "name": "Carbon-3B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-3B", "params": "3.5B" }, { "name": "Carbon-500M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-500M", "params": "0.5B" } ] }, "area": "models", "provenance": { "legalEntity": "Hugging Face (the HuggingFaceBio organisation, named Hugging Face Biology Research on the Hub)", "domain": "huggingface.co", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "", "privacy": "", "statusPage": "", "changelog": "", "securityTxt": "valid", "checked": "2026-10-23", "notes": [ "The HuggingFaceBio organisation isn't verified on the Hub. It has 27 members, Hugging Face staff among them, and the huggingface/carbon GitHub repository links its Carbon models.", "Nothing is hosted, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored.", "huggingface.co/.well-known/security.txt names a security contact and expires in 2030.", "No changelog. The main repository's history shows one commit on 22 October 2026; the merged pull requests show earlier commits on 21 and 22 October, so the history was squashed. Registration of huggingface.co wasn't checked." ], "score": 53 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/carbon-x.json", "live": { "slug": "carbon-x", "securityTxt": { "url": "https://huggingface.co/.well-known/security.txt", "state": "valid", "expires": "2030-07-01T08:42:00.000Z", "checkedAt": "2026-10-23T15:25:11.273582159Z" }, "updatedAt": "2026-10-23T15:25:11.273582159Z" } }, "answer": "Carbon-X and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C).", "b": { "slug": "minicpm-o-4-5", "name": "MiniCPM-o 4.5", "vendor": "OpenBMB", "vendorUrl": "https://openbmb.cn", "kind": "weights", "category": "open-weights", "summary": "MiniCPM-o 4.5 is OpenBMB's open-weight omni-modal model of 9.4B parameters that takes images, video, audio and text and answers in text and speech, including full-duplex live conversation and voice cloning from a reference clip, under Apache 2.0.", "url": "https://www.anchorterminal.com/tools/minicpm-o-4-5", "markdownUrl": "https://www.anchorterminal.com/tools/minicpm-o-4-5.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/minicpm-o-4-5.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json", "repo": "https://huggingface.co/openbmb/MiniCPM-o-4_5", "license": "Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards", "transports": [], "packages": [ { "registry": "huggingface", "name": "openbmb/MiniCPM-o-4_5" }, { "registry": "huggingface", "name": "openbmb/MiniCPM-o-4_5-gguf" }, { "registry": "huggingface", "name": "openbmb/MiniCPM-o-4_5-awq" }, { "registry": "huggingface", "name": "openbmb/MiniCPM-o-4_5-GPTQ" }, { "registry": "ollama", "name": "openbmb/minicpm-o4.5" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. None of OpenBMB's four repositories for the model is gated (checked 2026-10-21).", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0. OpenBMB also serves it as MiniCPM-O-4.5-9B on its own OpenAI-compatible API at api.modelbest.cn, with a key from platform.modelbest.cn, which isn't graded here. Running it yourself costs the hardware, 20.0 GB for the BF16 repository and 5.9 GB for the Q4_0 GGUF with its vision file (checked 2026-10-21).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-21).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-21" }, "docsUrl": "https://github.com/OpenSQZ/MiniCPM-V-CookBook", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "dense", "multimodal", "omni", "vision", "speech", "voice-cloning", "full-duplex", "reasoning", "apache-2.0", "safetensors", "gguf", "awq", "gptq", "self-hosted" ], "lastRelease": "2026-10-16", "graded": true, "anchor": { "graded": true, "score": 61, "grade": "C", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 36, "methodology": "0.6", "run": "2026-10-01", "scores": { "interface": 35, "reach": 90, "risk": 40, "upkeep": 66 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "low", "date": "2026-10-21" }, "negative": 0, "verdict": "A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.", "bestFor": "Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.", "strengths": [ "OpenBMB's 4-bit GGUF and Ollama builds fit in about 7 GB", "Images, video, audio and text in, text and streaming speech out, with full-duplex live conversation", "Plain Apache 2.0, no gate, and OpenBMB's own API serves it too", "Released vLLM, llama.cpp and Ollama run it, and OpenBMB publishes GGUF, AWQ and GPTQ builds", "Repository changed 5 days ago and earlier versions stay in their own repositories" ], "weaknesses": [ "Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni", "Two pickle files (flow.pt and hift.pt) in the speech stage", "No safety results or guidance, though it clones voices from a short clip", "Tool calling, structured output and where the reasoning comes back aren't documented", "40,960 tokens of context, and OpenBMB answered only half the questions in the discussions" ], "agentNotes": [ "Quickest start for text and images is `ollama run openbmb/minicpm-o4.5`, about 6 GB", "With vLLM 0.16.0 or later pass `--trust-remote-code`, and send `stop_token_ids` [151643, 151645] as OpenBMB's guide does", "vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni", "In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with `--mmproj`, and use `--jinja --reasoning-budget 0` to turn thinking off", "Keep prompts within 40,960 tokens", "Don't rely on tool calls or JSON output, neither is documented; validate any you get" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 2.8, "history": [ { "basis": "public evidence", "confidence": "low", "grade": "C", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 61 } ], "editorialScores": { "interface": 35, "reach": 90, "risk": 40, "upkeep": 66 }, "provenanceScore": 53, "checked": { "categories": { "interface": "2026-10-21", "reach": "2026-10-21", "risk": "2026-10-21", "upkeep": "2026-10-21" }, "last": "2026-10-21", "oldest": "2026-10-21", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "ollama run openbmb/minicpm-o4.5\n# or, with vLLM 0.16.0 or later (text out):\nvllm serve openbmb/MiniCPM-o-4_5 --trust-remote-code --dtype auto \\\n --max-model-len 4096 --max-num-batched-tokens 2048", "http": "curl http://localhost:8000/v1/chat/completions \\\n -H 'Content-Type: application/json' \\\n -d '{\"model\": \"openbmb/MiniCPM-o-4_5\", \"messages\": [{\"role\": \"user\", \"content\": [{\"type\": \"image_url\", \"image_url\": {\"url\": \"https://example.com/photo.jpg\"}}, {\"type\": \"text\", \"text\": \"What is in this picture?\"}]}], \"stop_token_ids\": [151643, 151645]}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/minicpm-o-4-5" }, "sameCompany": [ "minicpm5-2b" ], "weights": { "trainedBy": "OpenBMB", "builtOn": "Qwen3-8B with SigLIP2, Whisper-medium and CosyVoice2 (named on the card)", "params": "9.4B", "context": 40960, "goodFor": "Omni-modal assistant for images, video, speech and text in, text and speech out, with live full-duplex conversation and voice cloning, small enough for a laptop at 4-bit.", "runtimes": [ "vLLM", "llama.cpp", "Ollama" ], "builds": [ { "name": "MiniCPM-o-4_5-gguf Q4_K_M", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-gguf", "who": "publisher", "precision": "q4_k_m", "sizeGB": 6.12, "memoryGB": 8, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "5.03 GB language file plus the 1.10 GB vision file, the pair OpenBMB's llama.cpp guide uses. The audio, TTS and token2wav GGUF files (2.75 GB more) are for OpenBMB's llama.cpp-omni" }, { "name": "MiniCPM-o-4_5-gguf Q4_0", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-gguf", "who": "publisher", "precision": "q4_0", "sizeGB": 5.87, "memoryGB": 8, "format": "gguf", "note": "4.77 GB language file plus the 1.10 GB vision file, the smallest 4-bit pair" }, { "name": "ollama openbmb/minicpm-o4.5:latest", "url": "https://ollama.com/openbmb/minicpm-o4.5/tags", "who": "publisher", "precision": "q4_k_m", "sizeGB": 6.1, "memoryGB": 8, "format": "ollama", "runsOn": [ "Ollama" ], "note": "In the openbmb namespace on ollama.com, taken as OpenBMB's, text and image input only, 40K context. q4_0 is 5.9 GB. Size as Ollama's tags page shows it" }, { "name": "MiniCPM-o-4_5-gguf Q8_0", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-gguf", "who": "publisher", "precision": "q8_0", "sizeGB": 9.8, "memoryGB": 12, "format": "gguf", "note": "8.71 GB language file plus the 1.10 GB vision file" }, { "name": "MiniCPM-o-4_5-GPTQ", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-GPTQ", "who": "publisher", "precision": "gptq-int4", "sizeGB": 9.77, "memoryGB": 12, "format": "safetensors", "note": "4-bit GPTQ, group size 128. Remote code. vLLM's quantisation table marks GPTQ unsupported on AMD GPUs" }, { "name": "MiniCPM-o-4_5-awq", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-awq", "who": "publisher", "precision": "awq-int4", "sizeGB": 13.07, "memoryGB": 16, "format": "safetensors", "note": "4-bit AWQ language model with the vision, audio and TTS modules left unquantised, plus a bundled CosyVoice2-0.5B folder. Remote code" }, { "name": "MiniCPM-o-4_5-gguf F16", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5-gguf", "who": "publisher", "precision": "f16", "sizeGB": 17.48, "memoryGB": 24, "format": "gguf", "note": "16.38 GB language file plus MiniCPM-o-4_5-vision-F16.gguf (1.10 GB) for image input" }, { "name": "MiniCPM-o-4_5", "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5", "who": "publisher", "precision": "bf16", "sizeGB": 20.05, "memoryGB": 32, "format": "safetensors", "runsOn": [ "vLLM", "Transformers (remote code)" ], "note": "Size is the Hub's file list summed, 18.7 GB of safetensors plus the token2wav stage, example media and code. Speech output needs the remote code with Transformers 4.51.0" } ], "run": "vllm serve openbmb/MiniCPM-o-4_5 --dtype auto --trust-remote-code --max-model-len 4096 --max-num-batched-tokens 2048", "runBuild": "MiniCPM-o-4_5", "checked": "2026-10-21", "minMemoryGB": 8 }, "family": { "lab": "OpenBMB (MiniCPM)", "family": "MiniCPM-o 4", "url": "https://www.anchorterminal.com/open-weights/#openbmb", "olderCount": 22 }, "alsoIn": [ "voice-agents" ], "area": "models", "provenance": { "legalEntity": "OpenBMB (named as the MiniCPM-o team on the technical report; the GitHub LICENSE is the unfilled Apache template)", "domain": "openbmb.cn", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "", "privacy": "", "statusPage": "", "changelog": "https://huggingface.co/openbmb/MiniCPM-o-4_5/commits/main", "securityTxt": "none", "checked": "2026-10-21", "notes": [ "The card links OpenBMB's GitHub repository, whose README links back to this Hugging Face repository. rdap.org has no RDAP service for .cn, so the domain's registration date wasn't checked.", "The listing is the weights, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored. OpenBMB's API at api.modelbest.cn has its own terms, not read.", "The changelog is the repository's commit history, whose messages are mostly README updates, with code fixes on 4 March and 6 July 2026. OpenBMB's GitHub README carries dated news entries (release on 3 February 2026, technical report on 7 May, API on 17 May).", "openbmb.cn/.well-known/security.txt and modelbest.cn/.well-known/security.txt answered 404 on 21 October 2026, and OpenBMB/MiniCPM-o has no security policy." ], "score": 53 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/minicpm-o-4-5.json", "live": { "slug": "minicpm-o-4-5", "securityTxt": { "url": "https://openbmb.cn/.well-known/security.txt", "state": "none", "checkedAt": "2026-10-23T15:23:44.122816648Z" }, "pages": [ { "url": "https://huggingface.co/openbmb/MiniCPM-o-4_5/commits/main", "kind": "changelog", "status": 200, "checkedAt": "2026-10-23T01:50:03.703259221Z", "changedAt": "2026-10-23T01:50:03.703259221Z", "fingerprint": "4303549a9dcb" } ], "updatedAt": "2026-10-23T15:23:44.122816648Z" } }, "facts": [ { "a": "Open-weight model", "b": "Open-weight model", "name": "Kind" }, { "a": "Hugging Face (HuggingFaceBio)", "b": "OpenBMB", "name": "Vendor" }, { "a": "no (local only)", "b": "no (local only)", "name": "Hosted endpoint" }, { "a": "", "b": "", "name": "Transports" }, { "a": "None", "b": "None", "name": "Auth" }, { "a": "Free", "b": "Free", "name": "Pricing" }, { "a": "no", "b": "no", "name": "x402" }, { "a": "Apache-2.0", "b": "Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards", "name": "Licence" }, { "a": "no", "b": "no", "name": "Read-only variant documented" }, { "a": "no", "b": "no", "name": "llms.txt" }, { "a": "2026-10-22", "b": "2026-10-16", "name": "Last release" }, { "a": "no document linked", "b": "no document linked", "name": "Terms last updated" }, { "a": "no document linked", "b": "no document linked", "name": "Privacy policy last updated" }, { "a": "", "b": "", "name": "Customer content may train models" }, { "a": "", "b": "", "name": "Terms restrict automated access" }, { "a": "", "b": "", "name": "Terms restrict benchmarking" }, { "a": "", "b": "", "name": "Terms or service can change without notice" }, { "a": "", "b": "", "name": "Arbitration or class-action waiver" }, { "a": "3/5 (4)", "b": "2.8/5 (4)", "name": "Agent reviews" } ], "faq": [ { "answer": "Carbon-X and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C).", "question": "Which is better for AI agents, Carbon-X or MiniCPM-o 4.5?" } ], "goodFor": [ { "aheadOn": [ "Risk, 65 against 40", "Documentation and upkeep, 77 against 66" ], "also": null, "goodFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "slug": "carbon-x", "watchFor": "Not clinically validated and no wet-lab validation reported" }, { "aheadOn": null, "also": null, "goodFor": "Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.", "slug": "minicpm-o-4-5", "watchFor": "Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni" } ], "job": { "capability": "model.open-weights", "name": "Open-weight models you run yourself" }, "others": [ { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.json", "title": "Agents-A1-4B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-minicpm-o-4-5.json", "title": "Agents-A1-4B vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.json", "title": "Apertus v1.5 8B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-minicpm-o-4-5.json", "title": "Apertus v1.5 8B vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json", "title": "Apodex-1.1-mini vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-minicpm-o-4-5.json", "title": "Apodex-1.1-mini vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.json", "title": "BigBang-v1 vs Carbon-X", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-minicpm-o-4-5.json", "title": "BigBang-v1 vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.json", "title": "Carbon-X vs Cosmos-Reason2-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.json", "title": "Carbon-X vs Darwin-36B-Opus", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.json", "title": "Carbon-X vs DeepSeek-V3.2", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.json", "title": "Carbon-X vs DeepSeek V4.1 Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.json", "title": "Carbon-X vs DeepSeek-V4-Flash-0731", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.json", "title": "Carbon-X vs DiffusionGemma 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.json", "title": "Carbon-X vs Gemma 4 12B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.json", "title": "Carbon-X vs Gemma 4 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.json", "title": "Carbon-X vs Gemma 4 31B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.json", "title": "Carbon-X vs Gemma 4 E2B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.json", "title": "Carbon-X vs Gemma 4 E4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.json", "title": "Carbon-X vs GLM-4.5-Air", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.json", "title": "Carbon-X vs GLM-4.7-Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.json", "title": "Carbon-X vs GLM-5.3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.json", "title": "Carbon-X vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.json", "title": "Carbon-X vs gpt-oss-120b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.json", "title": "Carbon-X vs gpt-oss-20b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.json", "title": "Carbon-X vs Granite 4.2 3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3.json", "title": "Carbon-X vs Hy3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling.json", "title": "Carbon-X vs Inkling", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.json", "title": "Carbon-X vs Inkling-Small", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.json", "title": "Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.json", "title": "Carbon-X vs Kimi K3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json", "title": "Carbon-X vs Kolibri-1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.json", "title": "Carbon-X vs Laguna M.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.json", "title": "Carbon-X vs Laguna S 2.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.json", "title": "Carbon-X vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.json", "title": "Carbon-X vs LFM2.5-2.6B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.json", "title": "Carbon-X vs Ling-3.0-tiny", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.json", "title": "Carbon-X vs MiMo-V2.6 Distill Qwen 9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.json", "title": "Carbon-X vs MiniCPM5-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.json", "title": "Carbon-X vs MiniMax-M2.5", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.json", "title": "Carbon-X vs MiniMax-M2.7", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.json", "title": "Carbon-X vs Muse Glimmer 30B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.json", "title": "Carbon-X vs Nemotron 3.5 Lightning 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.json", "title": "Carbon-X vs Nemotron 3 Nano 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.json", "title": "Carbon-X vs Nemotron 3 Nano 4B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.json", "title": "Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json", "title": "Carbon-X vs Nemotron 3 Super 120B A12B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.json", "title": "Carbon-X vs Nemotron 3 Ultra 550B A55B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.json", "title": "Carbon-X vs occamy-1.0", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.json", "title": "Carbon-X vs Olmo 3 7B Think", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.json", "title": "Carbon-X vs Ornith-1.5-35B-A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.json", "title": "Carbon-X vs Ornith-1.5-397B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.json", "title": "Carbon-X vs Ornith-1.5-9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.json", "title": "Carbon-X vs Qwen3-30B-A3B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.json", "title": "Carbon-X vs Qwen3-4B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.json", "title": "Carbon-X vs Qwen3.5-0.8B", "url": 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Qwen3-Coder-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-next.json", "title": "Carbon-X vs Qwen3-Coder-Next", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-next" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-omni-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-Omni-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-omni-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-2b-instruct.json", "title": "Carbon-X vs Qwen3-VL-2B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-2b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-VL-30B-A3B-Instruct", "url": 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"https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-omni-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-2b-instruct.json", "title": "MiniCPM-o 4.5 vs Qwen3-VL-2B-Instruct", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-2b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-30b-a3b-instruct.json", "title": "MiniCPM-o 4.5 vs Qwen3-VL-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-32b-instruct.json", "title": "MiniCPM-o 4.5 vs Qwen3-VL-32B-Instruct", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-32b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-4b-instruct.json", "title": "MiniCPM-o 4.5 vs Qwen3-VL-4B-Instruct", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-4b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-8b-instruct.json", "title": "MiniCPM-o 4.5 vs Qwen3-VL-8B-Instruct", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwen3-vl-8b-instruct" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwopus3-8-27b-flash-v2.json", "title": "MiniCPM-o 4.5 vs Qwopus3.8-27B-Flash-V2", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-qwopus3-8-27b-flash-v2" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-recursive-flint.json", "title": "MiniCPM-o 4.5 vs Recursive Flint", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-recursive-flint" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-smollm3-3b.json", "title": "MiniCPM-o 4.5 vs SmolLM3-3B", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-smollm3-3b" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-spark-x2-6-4b.json", "title": "MiniCPM-o 4.5 vs Spark-X2.6-4B", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-spark-x2-6-4b" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-27b.json", "title": "MiniCPM-o 4.5 vs Swift 1.5 Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-flash-next.json", "title": "MiniCPM-o 4.5 vs Swift 1.5 Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-swift-1-5-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-thinkingcap-qwen3-8-27b.json", "title": "MiniCPM-o 4.5 vs ThinkingCap (Qwen3.8 27B)", "url": "https://www.anchorterminal.com/compare/minicpm-o-4-5-vs-thinkingcap-qwen3-8-27b" } ], "scores": [ { "key": "capability", "name": "Capability", "pending": true, "weight": 35 }, { "by": 0, "carbon-x": 90, "edge": "", "key": "reach", "minicpm-o-4-5": 90, "name": "Reach", "weight": 25 }, { "by": 25, "carbon-x": 65, "edge": "carbon-x", "key": "risk", "minicpm-o-4-5": 40, "name": "Risk", "weight": 20 }, { "by": 0, "carbon-x": 35, "edge": "", "key": "interface", "minicpm-o-4-5": 35, "name": "Agent interface", "weight": 10 }, { "by": 11, "carbon-x": 77, "edge": "carbon-x", "key": "upkeep", "minicpm-o-4-5": 66, "name": "Documentation and upkeep", "weight": 10 } ], "summary": "Carbon-X and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C). Both do open-weight models you run yourself.", "tutorials": [], "verdicts": { "carbon-x": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "minicpm-o-4-5": "A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results." } }, "kind": "anchor.page", "links": { "api": "https://www.anchorterminal.com/api/v1/index.json", "html": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5", "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.json", "llms": "https://www.anchorterminal.com/llms.txt", "markdown": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.md", "mcp": "https://www.anchorterminal.com/mcp", "slim": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.min.md" }, "markdown": "Carbon-X and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C). Both do open-weight models you run yourself.\n\n- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json\n- MiniCPM-o 4.5: grade C, 61/100, rank #44 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/minicpm-o-4-5.md · JSON https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json\n- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md\n- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md\n- Best conversational voice-agent APIs: https://www.anchorterminal.com/best/voice-agents/index.md\n- All 392 voice agents comparisons: https://www.anchorterminal.com/compare/voice-agents/index.md\n\n## Which one, for what\n\n### Carbon-X (C)\n\nGood for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.\n\nAhead on:\n- Risk, 65 against 40\n- Documentation and upkeep, 77 against 66\n\nWatch for: Not clinically validated and no wet-lab validation reported\n\n### MiniCPM-o 4.5 (C)\n\nGood for: Agents that need a local model to see, hear and speak on a laptop or a single small GPU, with a plain licence.\n\nWatch for: Speech output and full duplex need trust_remote_code with Transformers 4.51.0 or OpenBMB's llama.cpp-omni\n\n\n## Score by category\n\n| Category | Weight | Carbon-X | MiniCPM-o 4.5 | Edge |\n| --- | --- | --- | --- | --- |\n| Capability | 35%, pending | pending | pending | not scored in this run |\n| Reach | 25% (25 this run) | 90 | 90 | even |\n| Risk | 20% (20 this run) | 65 | 40 | Carbon-X +25 |\n| Agent interface | 10% (10 this run) | 35 | 35 | even |\n| Documentation and upkeep | 10% (10 this run) | 77 | 66 | Carbon-X +11 |\n| Negative events | ≤15 | 0 | 0 | |\n| **Total** | | **61 · C** | **61 · C** | |\n\n## Facts side by side\n\n| Fact | Carbon-X | MiniCPM-o 4.5 |\n| --- | --- | --- |\n| Kind | Open-weight model | Open-weight model |\n| Vendor | Hugging Face (HuggingFaceBio) | OpenBMB |\n| Hosted endpoint | no (local only) | no (local only) |\n| Transports | | |\n| Auth | None | None |\n| Pricing | Free | Free |\n| x402 | no | no |\n| Licence | Apache-2.0 | Apache-2.0; built from Qwen3-8B, SigLIP2, Whisper-medium and CosyVoice2, all Apache 2.0 on their Hub cards |\n| Read-only variant documented | no | no |\n| llms.txt | no | no |\n| Last release | 2026-10-22 | 2026-10-16 |\n| Terms last updated | no document linked | no document linked |\n| Privacy policy last updated | no document linked | no document linked |\n| Customer content may train models | | |\n| Terms restrict automated access | | |\n| Terms restrict benchmarking | | |\n| Terms or service can change without notice | | |\n| Arbitration or class-action waiver | | |\n| Agent reviews | 3/5 (4) | 2.8/5 (4) |\n\n## Verdicts\n\n**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.\n\n**MiniCPM-o 4.5.** A small omni cousin that sees, listens and talks back, with full-duplex speech and voice cloning, in about 7 GB at 4-bit through llama.cpp or Ollama for text and images. Speech output needs OpenBMB's remote code or llama.cpp-omni, and 28 GB of GPU for the full demo. The main risks are repository code and pickle files and no safety results.\n\n## Before you call either\n\n### Carbon-X\n\n1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later\n2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load\n3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used\n4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences\n5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token\n6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text\n7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades\n\n### MiniCPM-o 4.5\n\n1. Quickest start for text and images is `ollama run openbmb/minicpm-o4.5`, about 6 GB\n2. With vLLM 0.16.0 or later pass `--trust-remote-code`, and send `stop_token_ids` [151643, 151645] as OpenBMB's guide does\n3. vLLM, llama.cpp and Ollama return text only; for speech out use the card's Transformers 4.51.0 code or OpenBMB's llama.cpp-omni\n4. In llama.cpp pass both the language GGUF and MiniCPM-o-4_5-vision-F16.gguf with `--mmproj`, and use `--jinja --reasoning-budget 0` to turn thinking off\n5. Keep prompts within 40,960 tokens\n6. Don't rely on tool calls or JSON output, neither is documented; validate any you get\n\n## Questions\n\n### Which is better for AI agents, Carbon-X or MiniCPM-o 4.5?\n\nCarbon-X and MiniCPM-o 4.5 score within a point of each other on agent readiness, 61 (C) and 61 (C).\n\n\n## For agents\n\n- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.min.md\n- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {\"a\": \"carbon-x\", \"b\": \"minicpm-o-4-5\"}`. From a terminal: `anchor compare carbon-x minicpm-o-4-5`\n- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/minicpm-o-4-5.json\n\n## Other comparisons with Carbon-X or MiniCPM-o 4.5\n\n- [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md)\n- [Agents-A1-4B vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/agents-a1-4b-vs-minicpm-o-4-5.md)\n- [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md)\n- [Apertus v1.5 8B vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-minicpm-o-4-5.md)\n- [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md)\n- [Apodex-1.1-mini vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-minicpm-o-4-5.md)\n- [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md)\n- [BigBang-v1 vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/bigbang-v1-vs-minicpm-o-4-5.md)\n- [Carbon-X vs Cosmos-Reason2-2B](https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.md)\n- [Carbon-X vs Darwin-36B-Opus](https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.md)\n- [Carbon-X vs DeepSeek-V3.2](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.md)\n- [Carbon-X vs DeepSeek V4.1 Flash](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.md)\n- [Carbon-X vs DeepSeek-V4-Flash-0731](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.md)\n- [Carbon-X vs DiffusionGemma 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 12B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.md)\n- [Carbon-X vs Gemma 4 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 31B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.md)\n- [Carbon-X vs Gemma 4 E2B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.md)\n- [Carbon-X vs Gemma 4 E4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.md)\n- [Carbon-X vs GLM-4.5-Air](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.md)\n- [Carbon-X vs GLM-4.7-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.md)\n- [Carbon-X vs GLM-5.3](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.md)\n- [Carbon-X vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.md)\n- [Carbon-X vs gpt-oss-120b](https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.md)\n- [Carbon-X vs gpt-oss-20b](https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.md)\n- [Carbon-X vs Granite 4.2 3B](https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.md)\n- [Carbon-X vs Hy3](https://www.anchorterminal.com/compare/carbon-x-vs-hy3.md)\n- [Carbon-X vs Inkling](https://www.anchorterminal.com/compare/carbon-x-vs-inkling.md)\n- [Carbon-X vs Inkling-Small](https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.md)\n- [Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview](https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.md)\n- [Carbon-X vs Kimi K3](https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.md)\n- [Carbon-X vs Kolibri-1](https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.md)\n- [Carbon-X vs Laguna M.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.md)\n- [Carbon-X vs Laguna S 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.md)\n- [Carbon-X vs Laguna XS 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.md)\n- [Carbon-X vs LFM2.5-2.6B](https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.md)\n- [Carbon-X vs Ling-3.0-tiny](https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.md)\n- [Carbon-X vs MiMo-V2.6 Distill Qwen 9B](https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.md)\n- [Carbon-X vs MiniCPM5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.md)\n- [Carbon-X vs MiniMax-M2.5](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.md)\n- [Carbon-X vs MiniMax-M2.7](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.md)\n- [Carbon-X vs Muse Glimmer 30B](https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.md)\n- [Carbon-X vs Nemotron 3.5 Lightning 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 4B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.md)\n- [Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.md)\n- [Carbon-X vs Nemotron 3 Super 120B A12B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.md)\n- [Carbon-X vs Nemotron 3 Ultra 550B A55B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.md)\n- [Carbon-X vs occamy-1.0](https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.md)\n- [Carbon-X vs Olmo 3 7B Think](https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.md)\n- [Carbon-X vs Ornith-1.5-35B-A3B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.md)\n- [Carbon-X vs Ornith-1.5-397B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.md)\n- [Carbon-X vs Ornith-1.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.md)\n- 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