{ "data": { "a": { "slug": "carbon-x", "name": "Carbon-X", "vendor": "Hugging Face (HuggingFaceBio)", "vendorUrl": "https://huggingface.co/HuggingFaceBio", "kind": "weights", "category": "open-weights", "summary": "Carbon-X is Hugging Face's open-weight 14.8B language model for DNA, a fine-tune of Qwen3-14B that reads raw DNA in a chat and answers in English about variant effects and regulatory regions, with a 40,960-token context, under Apache 2.0.", "url": "https://www.anchorterminal.com/tools/carbon-x", "markdownUrl": "https://www.anchorterminal.com/tools/carbon-x.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/carbon-x.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/carbon-x.json", "repo": "https://huggingface.co/HuggingFaceBio/Carbon-X", "license": "Apache-2.0", "transports": [], "packages": [ { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X" }, { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X-GGUF" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The Hub reports gated false for HuggingFaceBio/Carbon-X and HuggingFaceBio/Carbon-X-GGUF (checked 2026-10-23). The Python tokenizer fetches Qwen/Qwen3-4B-Base's tokenizer at a pinned revision on first load, which is also ungated.", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0, and the base Qwen3-14B is Apache 2.0 too. Hugging Face sells no per-call access to it and no inference provider serves it. Running it costs the hardware, 29.6 GB for the BF16 safetensors and 9.6 GB for the publisher's smallest GGUF, Q4_K_M (checked 2026-10-23).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-23).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-23" }, "docsUrl": "https://huggingface.co/HuggingFaceBio/Carbon-X", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "dense", "dna", "genomics", "biology", "fine-tune", "apache-2.0", "safetensors", "gguf", "self-hosted" ], "lastRelease": "2026-10-22", "graded": true, "anchor": { "graded": true, "score": 61, "grade": "C", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 30, "methodology": "0.6", "run": "2026-10-01", "scores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "low", "date": "2026-10-23" }, "negative": 0, "verdict": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "bestFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "strengths": [ "Hugging Face's own GGUFs at four precisions, the smallest about 12 GB with a fifth added", "Runs in released llama.cpp, vLLM, SGLang and Transformers", "Apache 2.0 on the model and its Qwen3-14B base, nothing gated", "A ready-made skill, an OpenAI-style tool example and an Inspect example for calling it from another agent", "Mid-training data listed by source with shares of 302B tokens" ], "weaknesses": [ "Not clinically validated and no wet-lab validation reported", "The Python tokenizer needs trust_remote_code, and llama.cpp before b11742 tokenizes DNA wrongly", "Not trained for tool calling, structured output or reasoning", "The card says llama.cpp is unsupported while the publisher's GGUF repository says it is", "No inference provider or hosted API, and no knowledge cut-off" ], "agentNotes": [ "Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later", "With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load", "Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used", "Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences", "Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token", "Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text", "Cap max_tokens for next-base questions, long DNA generation is slow and degrades" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 3, "history": [ { "basis": "public evidence", "confidence": "low", "grade": "C", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 61 } ], "editorialScores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "provenanceScore": 53, "checked": { "categories": { "interface": "2026-10-23", "reach": "2026-10-23", "risk": "2026-10-23", "upkeep": "2026-10-23" }, "last": "2026-10-23", "oldest": "2026-10-23", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "# llama.cpp b11742 or later (older builds tokenize DNA wrongly):\nllama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja \\\n --chat-template-kwargs '{\"enable_thinking\": false}' \\\n --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080\n# or, with vLLM:\nvllm serve HuggingFaceBio/Carbon-X --trust-remote-code", "http": "curl http://localhost:8080/v1/chat/completions -H 'Content-Type: application/json' \\\n -d '{\"messages\": [{\"role\": \"user\", \"content\": \"Is this sequence more likely coding or non-coding? ATGGCGCTGTGGATGCGCCTCCTG\"}]}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/carbon-x" }, "sameCompany": [ "hugging-face-inference-endpoints", "smollm3-3b" ], "weights": { "trainedBy": "Hugging Face with Zhongguancun Academy and TIGEM / University of Naples Federico II", "builtOn": "Qwen/Qwen3-14B (vocabulary extension, mid-training, supervised fine-tune and GRPO; base Apache 2.0, declared in the card's metadata)", "params": "14.8B", "context": 40960, "goodFor": "A DNA specialist another agent calls, for variant-effect questions, regulatory regions and next-base prediction on raw DNA kept on local hardware.", "runtimes": [ "llama.cpp", "vLLM", "SGLang", "Transformers" ], "builds": [ { "name": "Carbon-X-GGUF Q4_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q4_k_m", "sizeGB": 9.64, "memoryGB": 12, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q4_k_m.gguf, 9,636,318,080 bytes. Embedding and output tensors stay at Q8_0. The publisher's own runs put it lowest of the builds on FrontierVEP (67.8) and NextBase (38.6)" }, { "name": "Carbon-X-GGUF Q6_K", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q6_k", "sizeGB": 12.56, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q6_k.gguf, 12,555,946,880 bytes" }, { "name": "Carbon-X-GGUF Q5_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q5_k_m", "sizeGB": 11.05, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q5_k_m.gguf, 11,051,895,680 bytes" }, { "name": "Carbon-X-GGUF Q8_0", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q8_0", "sizeGB": 15.76, "memoryGB": 24, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q8_0.gguf, 15,755,742,080 bytes, the build the publisher recommends" }, { "name": "Carbon-X", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X", "who": "publisher", "precision": "bf16", "sizeGB": 29.64, "memoryGB": 48, "format": "safetensors", "runsOn": [ "vLLM", "Transformers" ], "note": "Needs trust_remote_code for the custom HybridDNATokenizer, and Transformers v5 or later. The card says it fits one 80 GB GPU" }, { "name": "Carbon-X-GGUF BF16", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "bf16", "sizeGB": 29.65, "memoryGB": 48, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-bf16.gguf, 29,651,012,480 bytes. llama.cpp b11742 or later" } ], "run": "llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080", "runBuild": "Carbon-X-GGUF Q8_0", "checked": "2026-10-23", "minMemoryGB": 12 }, "family": { "lab": "Hugging Face (Carbon)", "family": "Carbon", "url": "https://www.anchorterminal.com/open-weights/#huggingface-bio", "others": [ { "name": "Carbon-A-1.2B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-A-1.2B", "params": "1.2B" }, { "name": "Carbon-8B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-8B", "params": "8.3B" }, { "name": "Carbon-3B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-3B", "params": "3.5B" }, { "name": "Carbon-500M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-500M", "params": "0.5B" } ] }, "area": "models", "provenance": { "legalEntity": "Hugging Face (the HuggingFaceBio organisation, named Hugging Face Biology Research on the Hub)", "domain": "huggingface.co", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "", "privacy": "", "statusPage": "", "changelog": "", "securityTxt": "valid", "checked": "2026-10-23", "notes": [ "The HuggingFaceBio organisation isn't verified on the Hub. It has 27 members, Hugging Face staff among them, and the huggingface/carbon GitHub repository links its Carbon models.", "Nothing is hosted, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored.", "huggingface.co/.well-known/security.txt names a security contact and expires in 2030.", "No changelog. The main repository's history shows one commit on 22 October 2026; the merged pull requests show earlier commits on 21 and 22 October, so the history was squashed. Registration of huggingface.co wasn't checked." ], "score": 53 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/carbon-x.json", "live": { "slug": "carbon-x", "securityTxt": { "url": "https://huggingface.co/.well-known/security.txt", "state": "valid", "expires": "2030-07-01T08:42:00.000Z", "checkedAt": "2026-10-23T15:25:11.273582159Z" }, "updatedAt": "2026-10-23T15:25:11.273582159Z" } }, "answer": "Carbon-X and Laguna XS 2.1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Laguna XS 2.1 leads on agent interface.", "b": { "slug": "laguna-xs-2-1", "name": "Laguna XS 2.1", "vendor": "Poolside", "vendorUrl": "https://poolside.ai", "kind": "weights", "category": "open-weights", "summary": "Laguna XS 2.1 is Poolside's open-weight Mixture-of-Experts coding model, 33B total and 3B active parameters, with switchable reasoning and a 262,144-token context, published on Hugging Face under OpenMDW-1.1.", "url": "https://www.anchorterminal.com/tools/laguna-xs-2-1", "markdownUrl": "https://www.anchorterminal.com/tools/laguna-xs-2-1.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/laguna-xs-2-1.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/laguna-xs-2-1.json", "repo": "https://huggingface.co/poolside/Laguna-XS-2.1", "license": "OpenMDW-1.1", "transports": [], "packages": [ { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1" }, { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1-FP8" }, { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1-INT4" }, { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1-NVFP4" }, { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1-NVFP4-mlx" }, { "registry": "huggingface", "name": "poolside/Laguna-XS-2.1-GGUF" }, { "registry": "ollama", "name": "laguna-xs-2.1" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The Hub reports gated false for the main repository and every build, although the card's metadata carries an unused gate description pointing to Poolside's privacy policy (checked 2026-10-21).", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under OpenMDW-1.1. Running it yourself costs the hardware, 66.9 GB for the BF16 files and 20.3 GB for Poolside's Q4_K_M GGUF, which is also Ollama's default build. Poolside serves it on OpenRouter with a free and a paid endpoint, both marked to expire on 31 October 2026 (checked 2026-10-21).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-21).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-21" }, "docsUrl": "https://huggingface.co/poolside/Laguna-XS-2.1", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "moe", "coding", "reasoning", "tool-calling", "openmdw-1.1", "safetensors", "gguf", "fp8", "nvfp4", "self-hosted" ], "lastRelease": "2026-08-19", "graded": true, "anchor": { "graded": true, "score": 61, "grade": "C", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 34, "methodology": "0.6", "run": "2026-10-01", "scores": { "interface": 85, "reach": 85, "risk": 55, "upkeep": 46 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "low", "date": "2026-10-21" }, "negative": 0, "verdict": "A small coding and agent cousin with 3B active parameters, so it's quick on modest hardware. Poolside's 4-bit GGUF, also Ollama's default, needs about 24 GB, and every major runtime runs it. The main risks are that nobody at Poolside answers its discussions, there are no safety results, and the SGLang route runs repository code.", "bestFor": "Agents that want a fast local coding model on a 32 GB GPU or Mac, with tool calling and a permissive licence.", "strengths": [ "Released support in llama.cpp, Ollama, vLLM, SGLang, Transformers and mlx-lm", "Poolside's own Q4_K_M, FP8, INT4, NVFP4 and MLX builds, the Q4_K_M at 20.3 GB", "Permissive OpenMDW-1.1 licence with no gate, account or use policy", "Tool calling and the poolside_v1 parser documented on the card, several calls a turn", "Thinking on or off per request, with the reasoning returned in reasoning_content" ], "weaknesses": [ "No reply from Poolside to any discussion, including reports about the tokenizer and remote code", "No safety results and only general cautions for agent use", "The SGLang and TensorRT-LLM commands run the repository's Python with trust_remote_code", "The template defaults thinking off while generation_config.json turns it on", "No structured output documentation, and no limitations, languages or cut-off on the card" ], "agentNotes": [ "Quickest start is `ollama run laguna-xs-2.1`, 20 GB of files, the same Q4_K_M as Poolside's GGUF", "On our reference machine use `llama-server -hf poolside/Laguna-XS-2.1-GGUF:Q4_K_M --jinja -c 131072`, from a llama.cpp release with the laguna architecture (b11772 has it), or BF16 with vLLM (66.9 GB)", "With vLLM use `--tool-call-parser poolside_v1 --reasoning-parser poolside_v1 --enable-auto-tool-choice`, on a build with vllm-project/vllm#47311, or `--tool-call-parser glm47` on older builds", "Thinking is off in the template unless you pass `enable_thinking` true or start the server with `--default-chat-template-kwargs '{\"enable_thinking\": true}'`, which Poolside recommends for agentic coding", "Pass earlier reasoning back as `reasoning_content` in the history, since the card says reasoning may stop in later steps if it's dropped", "Sampling per the card is temperature 1.0 and top_k 20", "The card warns that Ollama on Apple Silicon may return empty output until llama.cpp#25389 ships", "Validate JSON output yourself or use the runtime's guided decoding, since structured output isn't documented" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 2.8, "history": [ { "basis": "public evidence", "confidence": "low", "grade": "C", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 61 } ], "editorialScores": { "interface": 85, "reach": 85, "risk": 55, "upkeep": 46 }, "provenanceScore": 71, "checked": { "categories": { "interface": "2026-10-21", "reach": "2026-10-21", "risk": "2026-10-21", "upkeep": "2026-10-21" }, "last": "2026-10-21", "oldest": "2026-10-21", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "ollama run laguna-xs-2.1\n# or, with vLLM 0.21.0 or later (a build with vllm-project/vllm#47311):\nvllm serve poolside/Laguna-XS-2.1 --tool-call-parser poolside_v1 --reasoning-parser poolside_v1 \\\n --enable-auto-tool-choice --default-chat-template-kwargs '{\"enable_thinking\": true}'", "http": "curl http://localhost:11434/api/chat \\\n -d '{\"model\": \"laguna-xs-2.1\", \"messages\": [{\"role\": \"user\", \"content\": \"Hello!\"}]}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/laguna-xs-2-1" }, "sameCompany": [ "laguna-m-1", "laguna-s-2-1" ], "weights": { "trainedBy": "Poolside", "params": "33.4B total, 3B active", "context": 262144, "goodFor": "Agentic coding and long-horizon terminal work on one GPU or a 32 GB machine, with tool calling and reasoning that turns on or off per request.", "runtimes": [ "llama.cpp", "Ollama", "vLLM", "SGLang", "LM Studio", "Transformers" ], "builds": [ { "name": "Laguna-XS-2.1-INT4", "url": "https://huggingface.co/poolside/Laguna-XS-2.1-INT4", "who": "publisher", "precision": "int4 (w4a16)", "sizeGB": 23.9, "memoryGB": 32, "format": "safetensors" }, { "name": "Laguna-XS-2.1-NVFP4", "url": "https://huggingface.co/poolside/Laguna-XS-2.1-NVFP4", "who": "publisher", "precision": "nvfp4", "sizeGB": 21.6, "memoryGB": 32, "format": "safetensors", "note": "For NVIDIA Blackwell GPUs" }, { "name": "Laguna-XS-2.1-NVFP4-mlx", "url": "https://huggingface.co/poolside/Laguna-XS-2.1-NVFP4-mlx", "who": "publisher", "precision": "nvfp4", "sizeGB": 21.6, "memoryGB": 32, "format": "mlx", "runsOn": [ "MLX" ] }, { "name": "Laguna-XS-2.1-GGUF Q4_K_M", "url": "https://huggingface.co/poolside/Laguna-XS-2.1-GGUF", "who": "publisher", "precision": "q4_k_m", "sizeGB": 20.3, "memoryGB": 32, "format": "gguf", "runsOn": [ "llama.cpp", "Ollama" ], "note": "Laguna-XS-2.1-Q4_K_M.gguf, 20,274,300,032 bytes. The repository also holds a BF16 GGUF of 66.9 GB (96 GB of memory)" }, { "name": "ollama laguna-xs-2.1:latest", "url": "https://ollama.com/library/laguna-xs-2.1:latest", "who": "ollama", "precision": "q4_k_m", "sizeGB": 20.3, "memoryGB": 32, "format": "ollama", "runsOn": [ "Ollama" ], "note": "Ollama shows 20 GB. Its model blob (sha256 1ac7079101fc) is Poolside's Q4_K_M GGUF, so the exact size is Poolside's. The library also has q8_0 (36 GB), bf16 (67 GB) and MLX tags (nvfp4 shown as 20 GB, exact size unpublished, mxfp8 40 GB, mlx-bf16 68 GB). The card warns that ollama run may return empty output on Apple Silicon until llama.cpp#25389 ships" }, { "name": "Laguna-XS-2.1-FP8", "url": "https://huggingface.co/poolside/Laguna-XS-2.1-FP8", "who": "publisher", "precision": "fp8", "sizeGB": 35.3, "memoryGB": 48, "format": "safetensors" }, { "name": "Laguna-XS-2.1", "url": "https://huggingface.co/poolside/Laguna-XS-2.1", "who": "publisher", "precision": "bf16", "sizeGB": 66.9, "memoryGB": 96, "format": "safetensors", "runsOn": [ "vLLM", "SGLang", "Transformers" ] } ], "run": "llama-server -hf poolside/Laguna-XS-2.1-GGUF:Q4_K_M --jinja -c 131072 --port 8000", "runBuild": "Laguna-XS-2.1-GGUF Q4_K_M", "checked": "2026-10-21", "minMemoryGB": 32 }, "family": { "lab": "Poolside", "family": "Laguna 2 (XS.2, XS 2.1, S 2.1)", "url": "https://www.anchorterminal.com/open-weights/#poolside", "others": [ { "name": "Laguna-S-2.1", "url": "https://huggingface.co/poolside/Laguna-S-2.1", "params": "117.56B (Hub safetensors count; the name gives only the size class S)", "listing": "https://www.anchorterminal.com/tools/laguna-s-2-1" }, { "name": "Laguna-S-2.1-base", "url": "https://huggingface.co/poolside/Laguna-S-2.1-base", "params": "not stated (no safetensors count on the Hub; the instruct model is 117.56B)" }, { "name": "Laguna-XS.2", "url": "https://huggingface.co/poolside/Laguna-XS.2", "params": "33.44B (Hub safetensors count; the name gives only the size class XS)" } ], "unrestrictedCopies": 1 }, "area": "models", "provenance": { "legalEntity": "Poolside, Inc. (named in Poolside's Terms of Use)", "domain": "poolside.ai", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "https://poolside.ai/legal/eula", "privacy": "https://poolside.ai/legal/privacy", "statusPage": "", "changelog": "https://docs.poolside.ai/release-notes/models", "securityTxt": "valid", "checked": "2026-10-21", "notes": [ "The Hugging Face organisation poolside is verified, and Poolside's blog post for this release links its collection there.", "Nothing is hosted for this listing, so the OpenMDW-1.1 licence stands in for terms of service and no privacy policy is scored.", "Poolside's docs keep dated model release notes. The June 2026 entry calls XS 2.1 an incremental update to Laguna XS.2.", "security.txt is PGP-signed, names a security contact at poolside.ai and expires on 1 April 2028. The domain's registration date wasn't checked." ], "score": 71 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/laguna-xs-2-1.json", "live": { "slug": "laguna-xs-2-1", "securityTxt": { "url": "https://poolside.ai/.well-known/security.txt", "state": "valid", "expires": "2028-04-01T12:00:00.000Z", "checkedAt": "2026-10-23T15:24:50.518630429Z" }, "updatedAt": "2026-10-23T15:24:50.518630429Z" } }, "facts": [ { "a": "Open-weight model", "b": "Open-weight model", "name": "Kind" }, { "a": "Hugging Face (HuggingFaceBio)", "b": "Poolside", "name": "Vendor" }, { "a": "no (local only)", "b": "no (local only)", "name": "Hosted endpoint" }, { "a": "", "b": "", "name": "Transports" }, { "a": "None", "b": "None", "name": "Auth" }, { "a": "Free", "b": "Free", "name": "Pricing" }, { "a": "no", "b": "no", "name": "x402" }, { "a": "Apache-2.0", "b": "OpenMDW-1.1", "name": "Licence" }, { "a": "no", "b": "no", "name": "Read-only variant documented" }, { "a": "no", "b": "no", "name": "llms.txt" }, { "a": "2026-10-22", "b": "2026-08-19", "name": "Last release" }, { "a": "no document linked", "b": "", "name": "Terms last updated" }, { "a": "no document linked", "b": "", "name": "Privacy policy last updated" }, { "a": "", "b": "", "name": "Customer content may train models" }, { "a": "", "b": "", "name": "Terms restrict automated access" }, { "a": "", "b": "", "name": "Terms restrict benchmarking" }, { "a": "", "b": "", "name": "Terms or service can change without notice" }, { "a": "", "b": "", "name": "Arbitration or class-action waiver" }, { "a": "3/5 (4)", "b": "2.8/5 (4)", "name": "Agent reviews" } ], "faq": [ { "answer": "Carbon-X and Laguna XS 2.1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Laguna XS 2.1 leads on agent interface.", "question": "Which is better for AI agents, Carbon-X or Laguna XS 2.1?" } ], "goodFor": [ { "aheadOn": [ "Reach, 90 against 85", "Risk, 65 against 55", "Documentation and upkeep, 77 against 46" ], "also": null, "goodFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "slug": "carbon-x", "watchFor": "Not clinically validated and no wet-lab validation reported" }, { "aheadOn": [ "Agent interface, 85 against 35" ], "also": null, "goodFor": "Agents that want a fast local coding model on a 32 GB GPU or Mac, with tool calling and a permissive licence.", "slug": "laguna-xs-2-1", "watchFor": "No reply from Poolside to any discussion, including reports about the tokenizer and remote code" } ], "job": { "capability": "model.open-weights", "name": "Open-weight models you run yourself" }, "others": [ { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.json", "title": "Agents-A1-4B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-laguna-xs-2-1.json", "title": "Agents-A1-4B vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.json", "title": "Apertus v1.5 8B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-laguna-xs-2-1.json", "title": "Apertus v1.5 8B vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json", "title": "Apodex-1.1-mini vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-laguna-xs-2-1.json", "title": "Apodex-1.1-mini vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.json", "title": "BigBang-v1 vs Carbon-X", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-laguna-xs-2-1.json", "title": "BigBang-v1 vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.json", "title": "Carbon-X vs Cosmos-Reason2-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.json", "title": "Carbon-X vs Darwin-36B-Opus", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.json", "title": "Carbon-X vs DeepSeek-V3.2", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.json", "title": "Carbon-X vs DeepSeek V4.1 Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.json", "title": "Carbon-X vs DeepSeek-V4-Flash-0731", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.json", "title": "Carbon-X vs DiffusionGemma 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.json", "title": "Carbon-X vs Gemma 4 12B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.json", "title": "Carbon-X vs Gemma 4 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.json", "title": "Carbon-X vs Gemma 4 31B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.json", "title": "Carbon-X vs Gemma 4 E2B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.json", "title": "Carbon-X vs Gemma 4 E4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.json", "title": "Carbon-X vs GLM-4.5-Air", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.json", "title": "Carbon-X vs GLM-4.7-Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.json", "title": "Carbon-X vs GLM-5.3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.json", "title": "Carbon-X vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.json", "title": "Carbon-X vs gpt-oss-120b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.json", "title": "Carbon-X vs gpt-oss-20b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.json", "title": "Carbon-X vs Granite 4.2 3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3.json", "title": "Carbon-X vs Hy3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling.json", "title": "Carbon-X vs Inkling", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.json", "title": "Carbon-X vs Inkling-Small", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.json", "title": "Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.json", "title": "Carbon-X vs Kimi K3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json", "title": "Carbon-X vs Kolibri-1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.json", "title": "Carbon-X vs Laguna M.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.json", "title": "Carbon-X vs Laguna S 2.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.json", "title": "Carbon-X vs LFM2.5-2.6B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.json", "title": "Carbon-X vs Ling-3.0-tiny", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.json", "title": "Carbon-X vs MiMo-V2.6 Distill Qwen 9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.json", "title": "Carbon-X vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.json", "title": "Carbon-X vs MiniCPM5-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.json", "title": "Carbon-X vs MiniMax-M2.5", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.json", "title": "Carbon-X vs MiniMax-M2.7", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.json", "title": "Carbon-X vs Muse Glimmer 30B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.json", "title": "Carbon-X vs Nemotron 3.5 Lightning 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.json", "title": "Carbon-X vs Nemotron 3 Nano 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.json", "title": "Carbon-X vs Nemotron 3 Nano 4B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.json", "title": "Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json", "title": "Carbon-X vs Nemotron 3 Super 120B A12B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.json", "title": "Carbon-X vs Nemotron 3 Ultra 550B A55B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.json", "title": "Carbon-X vs occamy-1.0", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.json", "title": "Carbon-X vs Olmo 3 7B Think", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.json", "title": "Carbon-X vs Ornith-1.5-35B-A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.json", "title": "Carbon-X vs Ornith-1.5-397B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.json", "title": "Carbon-X vs Ornith-1.5-9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.json", "title": "Carbon-X vs Qwen3-30B-A3B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.json", "title": "Carbon-X vs Qwen3-4B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.json", "title": "Carbon-X vs Qwen3.5-0.8B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b.json", "title": "Carbon-X vs Qwen3.5-122B-A10B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b.json", "title": "Carbon-X vs Qwen3.5-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b.json", "title": "Carbon-X vs Qwen3.5-397B-A17B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b.json", "title": "Carbon-X vs Qwen3.5-4B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b.json", "title": "Carbon-X vs Qwen3.5-9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b.json", "title": "Carbon-X vs Qwen3.6-27B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-35b-a3b.json", "title": "Carbon-X vs Qwen3.6-35B-A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-27b.json", "title": "Carbon-X vs Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-flash-next.json", "title": "Carbon-X vs Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-Coder-30B-A3B-Instruct", "url": 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"https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-5-9b.json", "title": "Laguna XS 2.1 vs Qwen3.5-9B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-5-9b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-6-27b.json", "title": "Laguna XS 2.1 vs Qwen3.6-27B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-6-27b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-6-35b-a3b.json", "title": "Laguna XS 2.1 vs Qwen3.6-35B-A3B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-6-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-8-27b.json", "title": "Laguna XS 2.1 vs Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-8-flash-next.json", "title": "Laguna XS 2.1 vs Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-coder-30b-a3b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-Coder-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-coder-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-coder-next.json", "title": "Laguna XS 2.1 vs Qwen3-Coder-Next", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-coder-next" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-omni-30b-a3b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-Omni-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-omni-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-2b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-VL-2B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-2b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-30b-a3b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-VL-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-32b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-VL-32B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-32b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-4b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-VL-4B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-4b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-8b-instruct.json", "title": "Laguna XS 2.1 vs Qwen3-VL-8B-Instruct", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwen3-vl-8b-instruct" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwopus3-8-27b-flash-v2.json", "title": "Laguna XS 2.1 vs Qwopus3.8-27B-Flash-V2", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwopus3-8-27b-flash-v2" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-recursive-flint.json", "title": "Laguna XS 2.1 vs Recursive Flint", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-recursive-flint" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-smollm3-3b.json", "title": "Laguna XS 2.1 vs SmolLM3-3B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-smollm3-3b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-spark-x2-6-4b.json", "title": "Laguna XS 2.1 vs Spark-X2.6-4B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-spark-x2-6-4b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-27b.json", "title": "Laguna XS 2.1 vs Swift 1.5 Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-flash-next.json", "title": "Laguna XS 2.1 vs Swift 1.5 Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-thinkingcap-qwen3-8-27b.json", "title": "Laguna XS 2.1 vs ThinkingCap (Qwen3.8 27B)", "url": "https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-thinkingcap-qwen3-8-27b" } ], "scores": [ { "key": "capability", "name": "Capability", "pending": true, "weight": 35 }, { "by": 5, "carbon-x": 90, "edge": "carbon-x", "key": "reach", "laguna-xs-2-1": 85, "name": "Reach", "weight": 25 }, { "by": 10, "carbon-x": 65, "edge": "carbon-x", "key": "risk", "laguna-xs-2-1": 55, "name": "Risk", "weight": 20 }, { "by": 50, "carbon-x": 35, "edge": "laguna-xs-2-1", "key": "interface", "laguna-xs-2-1": 85, "name": "Agent interface", "weight": 10 }, { "by": 31, "carbon-x": 77, "edge": "carbon-x", "key": "upkeep", "laguna-xs-2-1": 46, "name": "Documentation and upkeep", "weight": 10 } ], "summary": "Carbon-X and Laguna XS 2.1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Laguna XS 2.1 leads on agent interface. Both do open-weight models you run yourself.", "tutorials": [], "verdicts": { "carbon-x": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "laguna-xs-2-1": "A small coding and agent cousin with 3B active parameters, so it's quick on modest hardware. Poolside's 4-bit GGUF, also Ollama's default, needs about 24 GB, and every major runtime runs it. The main risks are that nobody at Poolside answers its discussions, there are no safety results, and the SGLang route runs repository code." } }, "kind": "anchor.page", "links": { "api": "https://www.anchorterminal.com/api/v1/index.json", "html": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1", "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.json", "llms": "https://www.anchorterminal.com/llms.txt", "markdown": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.md", "mcp": "https://www.anchorterminal.com/mcp", "slim": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.min.md" }, "markdown": "Carbon-X and Laguna XS 2.1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Laguna XS 2.1 leads on agent interface. Both do open-weight models you run yourself.\n\n- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json\n- Laguna XS 2.1: grade C, 61/100, rank #42 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/laguna-xs-2-1.md · JSON https://www.anchorterminal.com/api/v1/tools/laguna-xs-2-1.json\n- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md\n- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md\n\n## Which one, for what\n\n### Carbon-X (C)\n\nGood for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.\n\nAhead on:\n- Reach, 90 against 85\n- Risk, 65 against 55\n- Documentation and upkeep, 77 against 46\n\nWatch for: Not clinically validated and no wet-lab validation reported\n\n### Laguna XS 2.1 (C)\n\nGood for: Agents that want a fast local coding model on a 32 GB GPU or Mac, with tool calling and a permissive licence.\n\nAhead on:\n- Agent interface, 85 against 35\n\nWatch for: No reply from Poolside to any discussion, including reports about the tokenizer and remote code\n\n\n## Score by category\n\n| Category | Weight | Carbon-X | Laguna XS 2.1 | Edge |\n| --- | --- | --- | --- | --- |\n| Capability | 35%, pending | pending | pending | not scored in this run |\n| Reach | 25% (25 this run) | 90 | 85 | Carbon-X +5 |\n| Risk | 20% (20 this run) | 65 | 55 | Carbon-X +10 |\n| Agent interface | 10% (10 this run) | 35 | 85 | Laguna XS 2.1 +50 |\n| Documentation and upkeep | 10% (10 this run) | 77 | 46 | Carbon-X +31 |\n| Negative events | ≤15 | 0 | 0 | |\n| **Total** | | **61 · C** | **61 · C** | |\n\n## Facts side by side\n\n| Fact | Carbon-X | Laguna XS 2.1 |\n| --- | --- | --- |\n| Kind | Open-weight model | Open-weight model |\n| Vendor | Hugging Face (HuggingFaceBio) | Poolside |\n| Hosted endpoint | no (local only) | no (local only) |\n| Transports | | |\n| Auth | None | None |\n| Pricing | Free | Free |\n| x402 | no | no |\n| Licence | Apache-2.0 | OpenMDW-1.1 |\n| Read-only variant documented | no | no |\n| llms.txt | no | no |\n| Last release | 2026-10-22 | 2026-08-19 |\n| Terms last updated | no document linked | |\n| Privacy policy last updated | no document linked | |\n| Customer content may train models | | |\n| Terms restrict automated access | | |\n| Terms restrict benchmarking | | |\n| Terms or service can change without notice | | |\n| Arbitration or class-action waiver | | |\n| Agent reviews | 3/5 (4) | 2.8/5 (4) |\n\n## Verdicts\n\n**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.\n\n**Laguna XS 2.1.** A small coding and agent cousin with 3B active parameters, so it's quick on modest hardware. Poolside's 4-bit GGUF, also Ollama's default, needs about 24 GB, and every major runtime runs it. The main risks are that nobody at Poolside answers its discussions, there are no safety results, and the SGLang route runs repository code.\n\n## Before you call either\n\n### Carbon-X\n\n1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later\n2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load\n3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used\n4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences\n5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token\n6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text\n7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades\n\n### Laguna XS 2.1\n\n1. Quickest start is `ollama run laguna-xs-2.1`, 20 GB of files, the same Q4_K_M as Poolside's GGUF\n2. On our reference machine use `llama-server -hf poolside/Laguna-XS-2.1-GGUF:Q4_K_M --jinja -c 131072`, from a llama.cpp release with the laguna architecture (b11772 has it), or BF16 with vLLM (66.9 GB)\n3. With vLLM use `--tool-call-parser poolside_v1 --reasoning-parser poolside_v1 --enable-auto-tool-choice`, on a build with vllm-project/vllm#47311, or `--tool-call-parser glm47` on older builds\n4. Thinking is off in the template unless you pass `enable_thinking` true or start the server with `--default-chat-template-kwargs '{\"enable_thinking\": true}'`, which Poolside recommends for agentic coding\n5. Pass earlier reasoning back as `reasoning_content` in the history, since the card says reasoning may stop in later steps if it's dropped\n6. Sampling per the card is temperature 1.0 and top_k 20\n7. The card warns that Ollama on Apple Silicon may return empty output until llama.cpp#25389 ships\n8. Validate JSON output yourself or use the runtime's guided decoding, since structured output isn't documented\n\n## Questions\n\n### Which is better for AI agents, Carbon-X or Laguna XS 2.1?\n\nCarbon-X and Laguna XS 2.1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Laguna XS 2.1 leads on agent interface.\n\n\n## For agents\n\n- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.min.md\n- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {\"a\": \"carbon-x\", \"b\": \"laguna-xs-2-1\"}`. From a terminal: `anchor compare carbon-x laguna-xs-2-1`\n- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/laguna-xs-2-1.json\n\n## Other comparisons with Carbon-X or Laguna XS 2.1\n\n- [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md)\n- [Agents-A1-4B vs Laguna XS 2.1](https://www.anchorterminal.com/compare/agents-a1-4b-vs-laguna-xs-2-1.md)\n- [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md)\n- [Apertus v1.5 8B vs Laguna XS 2.1](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-laguna-xs-2-1.md)\n- [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md)\n- [Apodex-1.1-mini vs Laguna XS 2.1](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-laguna-xs-2-1.md)\n- [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md)\n- [BigBang-v1 vs Laguna XS 2.1](https://www.anchorterminal.com/compare/bigbang-v1-vs-laguna-xs-2-1.md)\n- [Carbon-X vs Cosmos-Reason2-2B](https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.md)\n- [Carbon-X vs Darwin-36B-Opus](https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.md)\n- [Carbon-X vs DeepSeek-V3.2](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.md)\n- [Carbon-X vs DeepSeek V4.1 Flash](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.md)\n- [Carbon-X vs DeepSeek-V4-Flash-0731](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.md)\n- [Carbon-X vs DiffusionGemma 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 12B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.md)\n- [Carbon-X vs Gemma 4 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 31B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.md)\n- [Carbon-X vs Gemma 4 E2B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.md)\n- [Carbon-X vs Gemma 4 E4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.md)\n- [Carbon-X vs GLM-4.5-Air](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.md)\n- [Carbon-X vs GLM-4.7-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.md)\n- [Carbon-X vs GLM-5.3](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.md)\n- [Carbon-X vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.md)\n- [Carbon-X vs gpt-oss-120b](https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.md)\n- [Carbon-X vs gpt-oss-20b](https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.md)\n- [Carbon-X vs Granite 4.2 3B](https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.md)\n- [Carbon-X vs Hy3](https://www.anchorterminal.com/compare/carbon-x-vs-hy3.md)\n- [Carbon-X vs Inkling](https://www.anchorterminal.com/compare/carbon-x-vs-inkling.md)\n- [Carbon-X vs Inkling-Small](https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.md)\n- [Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview](https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.md)\n- [Carbon-X vs Kimi K3](https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.md)\n- [Carbon-X vs Kolibri-1](https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.md)\n- [Carbon-X vs Laguna M.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.md)\n- [Carbon-X vs Laguna S 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.md)\n- [Carbon-X vs LFM2.5-2.6B](https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.md)\n- [Carbon-X vs Ling-3.0-tiny](https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.md)\n- [Carbon-X vs MiMo-V2.6 Distill Qwen 9B](https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.md)\n- [Carbon-X vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.md)\n- [Carbon-X vs MiniCPM5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.md)\n- [Carbon-X vs MiniMax-M2.5](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.md)\n- [Carbon-X vs MiniMax-M2.7](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.md)\n- [Carbon-X vs Muse Glimmer 30B](https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.md)\n- [Carbon-X vs Nemotron 3.5 Lightning 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 4B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.md)\n- [Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.md)\n- [Carbon-X vs Nemotron 3 Super 120B A12B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.md)\n- [Carbon-X vs Nemotron 3 Ultra 550B A55B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.md)\n- [Carbon-X vs occamy-1.0](https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.md)\n- [Carbon-X vs Olmo 3 7B Think](https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.md)\n- [Carbon-X vs Ornith-1.5-35B-A3B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.md)\n- [Carbon-X vs Ornith-1.5-397B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.md)\n- [Carbon-X vs Ornith-1.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.md)\n- 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Qwopus3.8-27B-Flash-V2](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-qwopus3-8-27b-flash-v2.md)\n- [Laguna XS 2.1 vs Recursive Flint](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-recursive-flint.md)\n- [Laguna XS 2.1 vs SmolLM3-3B](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-smollm3-3b.md)\n- [Laguna XS 2.1 vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-spark-x2-6-4b.md)\n- [Laguna XS 2.1 vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-27b.md)\n- [Laguna XS 2.1 vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-swift-1-5-qwen3-8-flash-next.md)\n- [Laguna XS 2.1 vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/laguna-xs-2-1-vs-thinkingcap-qwen3-8-27b.md)\n", "meta": { "attribution": "Anchor Terminal (https://www.anchorterminal.com)", "attributionRequired": true, "credit": "CC BY 4.0, credit Anchor Terminal and link the 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