# Carbon-X vs Kolibri-1

> Carbon-X and Kolibri-1 score within a point of each other for open-weight models you run yourself, 61 and 61 out of 100. Prices, MCP, x402, uptime and agent notes side by side.

- Canonical: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1
- Markdown: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.md (~5,850 tokens)
- Slim: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.min.md (~430 tokens, same facts, less prose, for token-sensitive contexts)
- JSON: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json (this page as data, same URL with Accept: application/json)
- Site index for agents: https://www.anchorterminal.com/llms.txt (full text: https://www.anchorterminal.com/llms-full.txt)
- API: https://www.anchorterminal.com/api/v1/index.json
- MCP: https://www.anchorterminal.com/mcp (the whole catalogue as tools, no key)
- Licence: CC BY 4.0, credit Anchor Terminal and link this page (https://www.anchorterminal.com/terms/#data)
- Updated: 2026-10-23

Carbon-X and Kolibri-1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Kolibri-1 leads on agent interface. Both do open-weight models you run yourself.

- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json
- Kolibri-1: grade C, 61/100, rank #40 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/kolibri-1.md · JSON https://www.anchorterminal.com/api/v1/tools/kolibri-1.json
- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md
- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md

## Which one, for what

### Carbon-X (C)

Good for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.

Ahead on:
- Reach, 90 against 60
- Documentation and upkeep, 77 against 70

Watch for: Not clinically validated and no wet-lab validation reported

### Kolibri-1 (C)

Good for: German and English agent work with tools on a machine with about 96 GB of accelerator memory and vLLM, where a permissive licence matters.

Ahead on:
- Agent interface, 90 against 35

Watch for: The smallest publisher build is FP8 at 78.8 GB, so it needs about 95 GB and won't fit a 64 GB machine


## Score by category

| Category | Weight | Carbon-X | Kolibri-1 | Edge |
| --- | --- | --- | --- | --- |
| Capability | 35%, pending | pending | pending | not scored in this run |
| Reach | 25% (25 this run) | 90 | 60 | Carbon-X +30 |
| Risk | 20% (20 this run) | 65 | 65 | even |
| Agent interface | 10% (10 this run) | 35 | 90 | Kolibri-1 +55 |
| Documentation and upkeep | 10% (10 this run) | 77 | 70 | Carbon-X +7 |
| Negative events | ≤15 | 0 | 0 | |
| **Total** | | **61 · C** | **61 · C** | |

## Facts side by side

| Fact | Carbon-X | Kolibri-1 |
| --- | --- | --- |
| Kind | Open-weight model | Open-weight model |
| Vendor | Hugging Face (HuggingFaceBio) | Aleph Alpha |
| Hosted endpoint | no (local only) | no (local only) |
| Transports |  |  |
| Auth | None | None |
| Pricing | Free | Free |
| x402 | no | no |
| Licence | Apache-2.0 | Apache-2.0 |
| Read-only variant documented | no | no |
| llms.txt | no | no |
| Last release | 2026-10-22 | 2026-10-19 |
| Terms last updated | no document linked | no document linked |
| Privacy policy last updated | no document linked | no document linked |
| Customer content may train models |  |  |
| Terms restrict automated access |  |  |
| Terms restrict benchmarking |  |  |
| Terms or service can change without notice |  |  |
| Arbitration or class-action waiver |  |  |
| Agent reviews | 3/5 (4) | 3.3/5 (4) |

## Verdicts

**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.

**Kolibri-1.** Kolibri-1 is a German and English reasoning model with a documented tool-call format, switchable thinking and a 262,144-token context, under Apache 2.0. Aleph Alpha's FP8 build needs about 95 GB and runs on vLLM through its plugin, Transformers 5.20 or recent llama.cpp. The main risk is no published safety results or security contact, and few repository answers.

## Before you call either

### Carbon-X

1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{"enable_thinking": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later
2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load
3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used
4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences
5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token
6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text
7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades

### Kolibri-1

1. Start it with pip install 'aleph-alpha-inference>=1' then vllm serve Aleph-Alpha/Kolibri-1 --kv-cache-dtype fp8 --reasoning-parser kolibri1 --tool-call-parser kolibri1 --enable-auto-tool-choice
2. Without the kolibri1 tool-call parser and enable-auto-tool-choice, tool calls come back as text in tool_call tags
3. The plugin supports one vLLM minor version, 0.29, so don't upgrade vLLM while it's installed
4. Thinking is on by default at high effort. Pass reasoning_effort none or enable_thinking false in chat_template_kwargs for short tasks
5. Recommended sampling is temperature 1.0, top_p 0.97 and top_k 128
6. Past 262,144 tokens, add --max-model-len 1048576 and the max_position_embeddings override in --hf-overrides, though Aleph Alpha recommends staying at or below 262,144
7. With Transformers 5.20 or later, tokenizer.parse_response returns the answer in content and the reasoning in thinking
8. On the reference machine the FP8 build fits by size, but no document confirms vLLM runs FP8 on gfx1151, and Aleph Alpha ships no GGUF for llama.cpp
9. Validate tool results in your own code, as the card asks

## Questions

### Which is better for AI agents, Carbon-X or Kolibri-1?

Carbon-X and Kolibri-1 score within a point of each other on agent readiness, 61 (C) and 61 (C). Kolibri-1 leads on agent interface.


## For agents

- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.min.md
- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {"a": "carbon-x", "b": "kolibri-1"}`. From a terminal: `anchor compare carbon-x kolibri-1`
- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/kolibri-1.json

## Other comparisons with Carbon-X or Kolibri-1

- [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md)
- [Agents-A1-4B vs Kolibri-1](https://www.anchorterminal.com/compare/agents-a1-4b-vs-kolibri-1.md)
- [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md)
- [Apertus v1.5 8B vs Kolibri-1](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-kolibri-1.md)
- [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md)
- [Apodex-1.1-mini vs Kolibri-1](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-kolibri-1.md)
- [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md)
- [BigBang-v1 vs Kolibri-1](https://www.anchorterminal.com/compare/bigbang-v1-vs-kolibri-1.md)
- [Carbon-X vs Cosmos-Reason2-2B](https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.md)
- [Carbon-X vs Darwin-36B-Opus](https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.md)
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- [Kolibri-1 vs Nemotron 3 Nano 4B](https://www.anchorterminal.com/compare/kolibri-1-vs-nemotron-3-nano-4b.md)
- [Kolibri-1 vs Nemotron 3 Nano Omni 30B A3B Reasoning](https://www.anchorterminal.com/compare/kolibri-1-vs-nemotron-3-nano-omni-30b-a3b-reasoning.md)
- [Kolibri-1 vs Nemotron 3 Super 120B A12B](https://www.anchorterminal.com/compare/kolibri-1-vs-nemotron-3-super-120b-a12b.md)
- [Kolibri-1 vs Nemotron 3 Ultra 550B A55B](https://www.anchorterminal.com/compare/kolibri-1-vs-nemotron-3-ultra-550b-a55b.md)
- [Kolibri-1 vs occamy-1.0](https://www.anchorterminal.com/compare/kolibri-1-vs-occamy-1-0.md)
- [Kolibri-1 vs Olmo 3 7B Think](https://www.anchorterminal.com/compare/kolibri-1-vs-olmo-3-7b-think.md)
- [Kolibri-1 vs Ornith-1.5-35B-A3B](https://www.anchorterminal.com/compare/kolibri-1-vs-ornith-1-5-35b-a3b.md)
- [Kolibri-1 vs Ornith-1.5-397B](https://www.anchorterminal.com/compare/kolibri-1-vs-ornith-1-5-397b.md)
- [Kolibri-1 vs Ornith-1.5-9B](https://www.anchorterminal.com/compare/kolibri-1-vs-ornith-1-5-9b.md)
- [Kolibri-1 vs Qwen3-30B-A3B-Instruct-2507](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-30b-a3b-instruct-2507.md)
- [Kolibri-1 vs Qwen3-4B-Instruct-2507](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-4b-instruct-2507.md)
- [Kolibri-1 vs Qwen3.5-0.8B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-0-8b.md)
- [Kolibri-1 vs Qwen3.5-122B-A10B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-122b-a10b.md)
- [Kolibri-1 vs Qwen3.5-2B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-2b.md)
- [Kolibri-1 vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-397b-a17b.md)
- [Kolibri-1 vs Qwen3.5-4B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-4b.md)
- [Kolibri-1 vs Qwen3.5-9B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-5-9b.md)
- [Kolibri-1 vs Qwen3.6-27B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-6-27b.md)
- [Kolibri-1 vs Qwen3.6-35B-A3B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-6-35b-a3b.md)
- [Kolibri-1 vs Qwen3.8-27B](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-8-27b.md)
- [Kolibri-1 vs Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-8-flash-next.md)
- [Kolibri-1 vs Qwen3-Coder-30B-A3B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-coder-30b-a3b-instruct.md)
- [Kolibri-1 vs Qwen3-Coder-Next](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-coder-next.md)
- [Kolibri-1 vs Qwen3-Omni-30B-A3B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-omni-30b-a3b-instruct.md)
- [Kolibri-1 vs Qwen3-VL-2B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-vl-2b-instruct.md)
- [Kolibri-1 vs Qwen3-VL-30B-A3B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-vl-30b-a3b-instruct.md)
- [Kolibri-1 vs Qwen3-VL-32B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-vl-32b-instruct.md)
- [Kolibri-1 vs Qwen3-VL-4B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-vl-4b-instruct.md)
- [Kolibri-1 vs Qwen3-VL-8B-Instruct](https://www.anchorterminal.com/compare/kolibri-1-vs-qwen3-vl-8b-instruct.md)
- [Kolibri-1 vs Qwopus3.8-27B-Flash-V2](https://www.anchorterminal.com/compare/kolibri-1-vs-qwopus3-8-27b-flash-v2.md)
- [Kolibri-1 vs Recursive Flint](https://www.anchorterminal.com/compare/kolibri-1-vs-recursive-flint.md)
- [Kolibri-1 vs SmolLM3-3B](https://www.anchorterminal.com/compare/kolibri-1-vs-smollm3-3b.md)
- [Kolibri-1 vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/kolibri-1-vs-spark-x2-6-4b.md)
- [Kolibri-1 vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/kolibri-1-vs-swift-1-5-qwen3-8-27b.md)
- [Kolibri-1 vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/kolibri-1-vs-swift-1-5-qwen3-8-flash-next.md)
- [Kolibri-1 vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/kolibri-1-vs-thinkingcap-qwen3-8-27b.md)

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