{
  "data": {
    "a": {
      "slug": "carbon-x",
      "name": "Carbon-X",
      "vendor": "Hugging Face (HuggingFaceBio)",
      "vendorUrl": "https://huggingface.co/HuggingFaceBio",
      "kind": "weights",
      "category": "open-weights",
      "summary": "Carbon-X is Hugging Face's open-weight 14.8B language model for DNA, a fine-tune of Qwen3-14B that reads raw DNA in a chat and answers in English about variant effects and regulatory regions, with a 40,960-token context, under Apache 2.0.",
      "url": "https://www.anchorterminal.com/tools/carbon-x",
      "markdownUrl": "https://www.anchorterminal.com/tools/carbon-x.md",
      "slimMarkdownUrl": "https://www.anchorterminal.com/tools/carbon-x.min.md",
      "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/carbon-x.json",
      "repo": "https://huggingface.co/HuggingFaceBio/Carbon-X",
      "license": "Apache-2.0",
      "transports": [],
      "packages": [
        {
          "registry": "huggingface",
          "name": "HuggingFaceBio/Carbon-X"
        },
        {
          "registry": "huggingface",
          "name": "HuggingFaceBio/Carbon-X-GGUF"
        }
      ],
      "auth": "none",
      "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The Hub reports gated false for HuggingFaceBio/Carbon-X and HuggingFaceBio/Carbon-X-GGUF (checked 2026-10-23). The Python tokenizer fetches Qwen/Qwen3-4B-Base's tokenizer at a pinned revision on first load, which is also ungated.",
      "pricing": "free",
      "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0, and the base Qwen3-14B is Apache 2.0 too. Hugging Face sells no per-call access to it and no inference provider serves it. Running it costs the hardware, 29.6 GB for the BF16 safetensors and 9.6 GB for the publisher's smallest GGUF, Q4_K_M (checked 2026-10-23).",
      "priceSummary": "Free",
      "where": "local",
      "x402": {
        "level": "no",
        "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-23).",
        "endpoints": []
      },
      "toolCount": null,
      "popularity": {
        "githubStars": null,
        "npmWeekly": null,
        "pypiWeekly": null,
        "asOf": "2026-10-23"
      },
      "docsUrl": "https://huggingface.co/HuggingFaceBio/Carbon-X",
      "capabilities": [
        "model.open-weights"
      ],
      "tags": [
        "open-weights",
        "model",
        "dense",
        "dna",
        "genomics",
        "biology",
        "fine-tune",
        "apache-2.0",
        "safetensors",
        "gguf",
        "self-hosted"
      ],
      "lastRelease": "2026-10-22",
      "graded": true,
      "anchor": {
        "graded": true,
        "score": 61,
        "grade": "C",
        "agentReady": false,
        "rank": 0,
        "ranked": false,
        "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools",
        "rankOf": 1201,
        "categoryRank": 30,
        "methodology": "0.6",
        "run": "2026-10-01",
        "scores": {
          "interface": 35,
          "reach": 90,
          "risk": 65,
          "upkeep": 77
        },
        "pending": [
          "performance",
          "tasks"
        ],
        "assessment": {
          "confidence": "low",
          "date": "2026-10-23"
        },
        "negative": 0,
        "verdict": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.",
        "bestFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.",
        "strengths": [
          "Hugging Face's own GGUFs at four precisions, the smallest about 12 GB with a fifth added",
          "Runs in released llama.cpp, vLLM, SGLang and Transformers",
          "Apache 2.0 on the model and its Qwen3-14B base, nothing gated",
          "A ready-made skill, an OpenAI-style tool example and an Inspect example for calling it from another agent",
          "Mid-training data listed by source with shares of 302B tokens"
        ],
        "weaknesses": [
          "Not clinically validated and no wet-lab validation reported",
          "The Python tokenizer needs trust_remote_code, and llama.cpp before b11742 tokenizes DNA wrongly",
          "Not trained for tool calling, structured output or reasoning",
          "The card says llama.cpp is unsupported while the publisher's GGUF repository says it is",
          "No inference provider or hosted API, and no knowledge cut-off"
        ],
        "agentNotes": [
          "Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later",
          "With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load",
          "Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used",
          "Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences",
          "Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token",
          "Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text",
          "Cap max_tokens for next-base questions, long DNA generation is slow and degrades"
        ],
        "metrics": {
          "kind": "local",
          "measured": false
        },
        "reviewCount": 4,
        "avgRating": 3,
        "history": [
          {
            "basis": "public evidence",
            "confidence": "low",
            "grade": "C",
            "methodology": "0.6",
            "pending": [
              "performance",
              "tasks"
            ],
            "run": "2026-10-01",
            "runLabel": "October 2026 research run",
            "score": 61
          }
        ],
        "editorialScores": {
          "interface": 35,
          "reach": 90,
          "risk": 65,
          "upkeep": 77
        },
        "provenanceScore": 53,
        "checked": {
          "categories": {
            "interface": "2026-10-23",
            "reach": "2026-10-23",
            "risk": "2026-10-23",
            "upkeep": "2026-10-23"
          },
          "last": "2026-10-23",
          "oldest": "2026-10-23",
          "stale": false,
          "staleAfterDays": 90
        }
      },
      "connect": {
        "install": "# llama.cpp b11742 or later (older builds tokenize DNA wrongly):\nllama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja \\\n  --chat-template-kwargs '{\"enable_thinking\": false}' \\\n  --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080\n# or, with vLLM:\nvllm serve HuggingFaceBio/Carbon-X --trust-remote-code",
        "http": "curl http://localhost:8080/v1/chat/completions -H 'Content-Type: application/json' \\\n  -d '{\"messages\": [{\"role\": \"user\", \"content\": \"Is this sequence more likely coding or non-coding? ATGGCGCTGTGGATGCGCCTCCTG\"}]}'"
      },
      "letme": {
        "capability": "https://letme.dev/model.open-weights",
        "tool": "https://letme.dev/carbon-x"
      },
      "sameCompany": [
        "hugging-face-inference-endpoints",
        "smollm3-3b"
      ],
      "weights": {
        "trainedBy": "Hugging Face with Zhongguancun Academy and TIGEM / University of Naples Federico II",
        "builtOn": "Qwen/Qwen3-14B (vocabulary extension, mid-training, supervised fine-tune and GRPO; base Apache 2.0, declared in the card's metadata)",
        "params": "14.8B",
        "context": 40960,
        "goodFor": "A DNA specialist another agent calls, for variant-effect questions, regulatory regions and next-base prediction on raw DNA kept on local hardware.",
        "runtimes": [
          "llama.cpp",
          "vLLM",
          "SGLang",
          "Transformers"
        ],
        "builds": [
          {
            "name": "Carbon-X-GGUF Q4_K_M",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF",
            "who": "publisher",
            "precision": "q4_k_m",
            "sizeGB": 9.64,
            "memoryGB": 12,
            "format": "gguf",
            "runsOn": [
              "llama.cpp"
            ],
            "note": "carbon-x-q4_k_m.gguf, 9,636,318,080 bytes. Embedding and output tensors stay at Q8_0. The publisher's own runs put it lowest of the builds on FrontierVEP (67.8) and NextBase (38.6)"
          },
          {
            "name": "Carbon-X-GGUF Q6_K",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF",
            "who": "publisher",
            "precision": "q6_k",
            "sizeGB": 12.56,
            "memoryGB": 16,
            "format": "gguf",
            "runsOn": [
              "llama.cpp"
            ],
            "note": "carbon-x-q6_k.gguf, 12,555,946,880 bytes"
          },
          {
            "name": "Carbon-X-GGUF Q5_K_M",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF",
            "who": "publisher",
            "precision": "q5_k_m",
            "sizeGB": 11.05,
            "memoryGB": 16,
            "format": "gguf",
            "runsOn": [
              "llama.cpp"
            ],
            "note": "carbon-x-q5_k_m.gguf, 11,051,895,680 bytes"
          },
          {
            "name": "Carbon-X-GGUF Q8_0",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF",
            "who": "publisher",
            "precision": "q8_0",
            "sizeGB": 15.76,
            "memoryGB": 24,
            "format": "gguf",
            "runsOn": [
              "llama.cpp"
            ],
            "note": "carbon-x-q8_0.gguf, 15,755,742,080 bytes, the build the publisher recommends"
          },
          {
            "name": "Carbon-X",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X",
            "who": "publisher",
            "precision": "bf16",
            "sizeGB": 29.64,
            "memoryGB": 48,
            "format": "safetensors",
            "runsOn": [
              "vLLM",
              "Transformers"
            ],
            "note": "Needs trust_remote_code for the custom HybridDNATokenizer, and Transformers v5 or later. The card says it fits one 80 GB GPU"
          },
          {
            "name": "Carbon-X-GGUF BF16",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF",
            "who": "publisher",
            "precision": "bf16",
            "sizeGB": 29.65,
            "memoryGB": 48,
            "format": "gguf",
            "runsOn": [
              "llama.cpp"
            ],
            "note": "carbon-x-bf16.gguf, 29,651,012,480 bytes. llama.cpp b11742 or later"
          }
        ],
        "run": "llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080",
        "runBuild": "Carbon-X-GGUF Q8_0",
        "checked": "2026-10-23",
        "minMemoryGB": 12
      },
      "family": {
        "lab": "Hugging Face (Carbon)",
        "family": "Carbon",
        "url": "https://www.anchorterminal.com/open-weights/#huggingface-bio",
        "others": [
          {
            "name": "Carbon-A-1.2B",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-A-1.2B",
            "params": "1.2B"
          },
          {
            "name": "Carbon-8B",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-8B",
            "params": "8.3B"
          },
          {
            "name": "Carbon-3B",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-3B",
            "params": "3.5B"
          },
          {
            "name": "Carbon-500M",
            "url": "https://huggingface.co/HuggingFaceBio/Carbon-500M",
            "params": "0.5B"
          }
        ]
      },
      "area": "models",
      "provenance": {
        "legalEntity": "Hugging Face (the HuggingFaceBio organisation, named Hugging Face Biology Research on the Hub)",
        "domain": "huggingface.co",
        "domainRegistered": "",
        "endpointOnVendorDomain": null,
        "terms": "",
        "privacy": "",
        "statusPage": "",
        "changelog": "",
        "securityTxt": "valid",
        "checked": "2026-10-23",
        "notes": [
          "The HuggingFaceBio organisation isn't verified on the Hub. It has 27 members, Hugging Face staff among them, and the huggingface/carbon GitHub repository links its Carbon models.",
          "Nothing is hosted, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored.",
          "huggingface.co/.well-known/security.txt names a security contact and expires in 2030.",
          "No changelog. The main repository's history shows one commit on 22 October 2026; the merged pull requests show earlier commits on 21 and 22 October, so the history was squashed. Registration of huggingface.co wasn't checked."
        ],
        "score": 53
      },
      "pageJsonUrl": "https://www.anchorterminal.com/tools/carbon-x.json",
      "live": {
        "slug": "carbon-x",
        "securityTxt": {
          "url": "https://huggingface.co/.well-known/security.txt",
          "state": "valid",
          "expires": "2030-07-01T08:42:00.000Z",
          "checkedAt": "2026-10-23T15:25:11.273582159Z"
        },
        "updatedAt": "2026-10-23T15:25:11.273582159Z"
      }
    },
    "answer": "gpt-oss-20b scores 69.9 (B) on agent readiness against Carbon-X's 61 (C), and leads in 2 of 4 scored categories. Carbon-X leads on documentation and upkeep.",
    "b": {
      "slug": "gpt-oss-20b",
      "name": "gpt-oss-20b",
      "vendor": "OpenAI",
      "vendorUrl": "https://openai.com",
      "kind": "weights",
      "category": "open-weights",
      "summary": "gpt-oss-20b is OpenAI's open-weight mixture-of-experts reasoning model, 21B parameters with 3.6B active and a 131,072-token context, published on Hugging Face in MXFP4 under Apache 2.0 and trained on the harmony prompt format.",
      "url": "https://www.anchorterminal.com/tools/gpt-oss-20b",
      "markdownUrl": "https://www.anchorterminal.com/tools/gpt-oss-20b.md",
      "slimMarkdownUrl": "https://www.anchorterminal.com/tools/gpt-oss-20b.min.md",
      "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/gpt-oss-20b.json",
      "repo": "https://huggingface.co/openai/gpt-oss-20b",
      "license": "Apache-2.0",
      "transports": [],
      "packages": [
        {
          "registry": "huggingface",
          "name": "openai/gpt-oss-20b"
        },
        {
          "registry": "ollama",
          "name": "gpt-oss:20b"
        },
        {
          "registry": "pypi",
          "name": "gpt-oss"
        },
        {
          "registry": "pypi",
          "name": "openai-harmony"
        }
      ],
      "auth": "none",
      "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The repository is not gated (checked 2026-10-21).",
      "pricing": "free",
      "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0 with a one-line usage policy that asks users to comply with applicable law. Running it yourself costs the hardware, about 13.8 GB of weights, and OpenAI says it runs within 16 GB of memory (checked 2026-10-21).",
      "priceSummary": "Free",
      "where": "local",
      "x402": {
        "level": "no",
        "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-21).",
        "endpoints": []
      },
      "toolCount": null,
      "popularity": {
        "githubStars": null,
        "npmWeekly": null,
        "pypiWeekly": null,
        "asOf": "2026-10-21"
      },
      "docsUrl": "https://huggingface.co/openai/gpt-oss-20b",
      "capabilities": [
        "model.open-weights"
      ],
      "tags": [
        "open-weights",
        "model",
        "moe",
        "reasoning",
        "tool-calling",
        "apache-2.0",
        "safetensors",
        "mxfp4",
        "self-hosted"
      ],
      "lastRelease": "2025-08-26",
      "graded": true,
      "anchor": {
        "graded": true,
        "score": 69.9,
        "grade": "B",
        "agentReady": false,
        "rank": 0,
        "ranked": false,
        "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools",
        "rankOf": 1201,
        "categoryRank": 6,
        "methodology": "0.6",
        "run": "2026-10-01",
        "scores": {
          "capability": 49,
          "interface": 90,
          "reach": 90,
          "risk": 85,
          "upkeep": 42
        },
        "pending": [
          "performance",
          "tasks"
        ],
        "assessment": {
          "confidence": "high",
          "date": "2026-10-21"
        },
        "negative": 0,
        "verdict": "gpt-oss-20b is a cousin for reasoning, coding and single tool calls with structured output, under plain Apache 2.0. It needs about 17 GB with a working context, and five inference providers serve it. The main risks are that it trails o4-mini at keeping system instructions above user ones, and OpenAI hasn't answered a report since August 2025.",
        "bestFor": "Local agents on a 24 GB GPU or Mac that want a permissive licence, wide runtime support and documented structured output, one tool call at a time",
        "strengths": [
          "Model code in released Transformers, vLLM, SGLang and llama.cpp, plus a 14 GB build in Ollama's library",
          "Fits a 24 GB machine at OpenAI's own MXFP4 precision, the one every evaluation used",
          "Apache 2.0 with no gate, no account and a usage policy that only asks users to follow the law",
          "Harmony guide documents tool declarations, call parsing, JSON Schema output and three reasoning levels, with OpenAI's own parser",
          "Trained on an instruction hierarchy against prompt injection, with OpenAI's results for it published"
        ],
        "weaknesses": [
          "No reply from OpenAI to any discussion since August 2025, and template reports wait unanswered",
          "One tool call per message",
          "Reasoning can be lowered but not switched off",
          "Only one quantised build from OpenAI, and its weights and template haven't changed since August 2025",
          "Safety results for this size are OpenAI's own, and it trails o4-mini on the instruction hierarchy"
        ],
        "agentNotes": [
          "Start it with `ollama run gpt-oss:20b` (the build that fits the reference machine), or `vllm serve openai/gpt-oss-20b` with a current vLLM release rather than the card's pinned vllm==0.10.1+gptoss wheel",
          "Use the harmony format through the chat template or openai-harmony; OpenAI says the model doesn't work correctly without it",
          "Parse tool calls and reasoning with openai-harmony; calls come on the commentary channel ending in `\u003c|call|\u003e`, reasoning on the analysis channel",
          "Set effort with `Reasoning: high` (or low, medium) in the system message, or `reasoning_effort` in the template; medium is the default",
          "Ask for JSON by putting a JSON Schema under `# Response Formats` in the developer message",
          "Drop earlier reasoning after a final answer but pass it back after tool calls, and don't show the analysis channel to users",
          "Expect one tool call per turn; run several in sequence rather than in parallel"
        ],
        "metrics": {
          "kind": "local",
          "measured": false
        },
        "reviewCount": 4,
        "avgRating": 3.5,
        "history": [
          {
            "basis": "public evidence",
            "confidence": "high",
            "grade": "B",
            "methodology": "0.6",
            "pending": [
              "performance",
              "tasks"
            ],
            "run": "2026-10-01",
            "runLabel": "October 2026 research run",
            "score": 69.9
          }
        ],
        "editorialScores": {
          "capability": 49,
          "interface": 90,
          "reach": 90,
          "risk": 85,
          "upkeep": 42
        },
        "provenanceScore": 87,
        "checked": {
          "categories": {
            "capability": "2026-10-21",
            "interface": "2026-10-21",
            "reach": "2026-10-21",
            "risk": "2026-10-21",
            "upkeep": "2026-10-21"
          },
          "last": "2026-10-21",
          "oldest": "2026-10-21",
          "stale": false,
          "staleAfterDays": 90
        }
      },
      "connect": {
        "install": "ollama run gpt-oss:20b\n# or with vLLM:\nvllm serve openai/gpt-oss-20b",
        "http": "curl http://localhost:11434/api/chat \\\n  -d '{\"model\": \"gpt-oss:20b\", \"messages\": [{\"role\": \"user\", \"content\": \"Hello!\"}]}'"
      },
      "letme": {
        "capability": "https://letme.dev/model.open-weights",
        "tool": "https://letme.dev/gpt-oss-20b"
      },
      "sameCompany": [
        "openai-api",
        "openai-embeddings",
        "openai-guardrails",
        "openai-moderation",
        "openai-image-api",
        "openai-sora",
        "openai-speech-to-text",
        "gpt-live",
        "openai-realtime",
        "openai-agents-sdk",
        "openai-decisions-api",
        "openai-codex",
        "gpt-oss-120b"
      ],
      "weights": {
        "trainedBy": "OpenAI",
        "params": "20.91B",
        "active": "3.61B",
        "context": 131072,
        "goodFor": "Text reasoning model for agents and coding, with function calling, built-in browser and Python tools and low, medium or high reasoning, in the harmony format.",
        "runtimes": [
          "llama.cpp",
          "Ollama",
          "vLLM",
          "SGLang",
          "Transformers"
        ],
        "builds": [
          {
            "name": "gpt-oss-20b",
            "url": "https://huggingface.co/openai/gpt-oss-20b",
            "who": "publisher",
            "precision": "mxfp4",
            "sizeGB": 13.8,
            "memoryGB": 24,
            "format": "safetensors",
            "note": "MoE weights in MXFP4, the rest BF16, the precision OpenAI evaluated. original/ and metal/ hold the same weights for OpenAI's reference code. vLLM's gpt-oss recipe lists MI300x, MI325x, MI355x and Radeon AI PRO R9700 on AMD, not gfx1151"
          },
          {
            "name": "ollama gpt-oss:20b",
            "url": "https://ollama.com/library/gpt-oss:20b",
            "who": "ollama",
            "precision": "mxfp4",
            "sizeGB": 14,
            "memoryGB": 24,
            "format": "ollama",
            "runsOn": [
              "Ollama"
            ],
            "note": "OpenAI's MXFP4 weights; the card links it. Size as Ollama's tags page shows it, rounded to whole GB above 10 GB; the Linux build is the llama.cpp variant"
          }
        ],
        "run": "ollama run gpt-oss:20b",
        "runBuild": "ollama gpt-oss:20b",
        "checked": "2026-10-21",
        "minMemoryGB": 24
      },
      "family": {
        "lab": "OpenAI",
        "family": "gpt-oss",
        "url": "https://www.anchorterminal.com/open-weights/#openai",
        "others": [
          {
            "name": "gpt-oss-120b",
            "url": "https://huggingface.co/openai/gpt-oss-120b",
            "params": "117B total, 5.1B active (MoE)",
            "listing": "https://www.anchorterminal.com/tools/gpt-oss-120b"
          },
          {
            "name": "gpt-oss-safeguard-120b",
            "url": "https://huggingface.co/openai/gpt-oss-safeguard-120b",
            "params": "117B total, 5.1B active (MoE)"
          },
          {
            "name": "gpt-oss-safeguard-20b",
            "url": "https://huggingface.co/openai/gpt-oss-safeguard-20b",
            "params": "21B total, 3.6B active (MoE)"
          }
        ],
        "olderCount": 6,
        "unrestrictedCopies": 5
      },
      "area": "models",
      "provenance": {
        "legalEntity": "OpenAI (named in USAGE_POLICY and the model card; the LICENSE file's copyright line is the unfilled Apache template)",
        "domain": "openai.com",
        "domainRegistered": "2007-01-19",
        "domainNote": "openai.com was registered in 2007, years before the company was founded in 2015, so domain age flatters it.",
        "endpointOnVendorDomain": null,
        "terms": "",
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        "statusPage": "",
        "changelog": "https://huggingface.co/openai/gpt-oss-20b/commits/main",
        "securityTxt": "valid",
        "checked": "2026-10-21",
        "notes": [
          "Nothing is hosted, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored.",
          "The changelog is the repository's commit history, whose messages say what changed for some commits (the chat template on 7 and 8 August 2025, `\u003c|call|\u003e` as an end token on 13 August 2025) and not for others (README updates).",
          "openai.com/.well-known/security.txt answered 200, signed, with a Bugcrowd contact and a coordinated disclosure policy, but no Expires field, which RFC 9116 requires. Recorded as valid, as on the openai-api listing, since the data has no value for a file without one.",
          "openai.com/index/introducing-gpt-oss/ and openai.com/open-models/ answered 403 to our reader on 21 October 2026, so OpenAI's announcement wasn't read."
        ],
        "score": 87
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      "pageJsonUrl": "https://www.anchorterminal.com/tools/gpt-oss-20b.json",
      "live": {
        "slug": "gpt-oss-20b",
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            "name": "gpt-oss",
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    "facts": [
      {
        "a": "Open-weight model",
        "b": "Open-weight model",
        "name": "Kind"
      },
      {
        "a": "Hugging Face (HuggingFaceBio)",
        "b": "OpenAI",
        "name": "Vendor"
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      {
        "a": "no (local only)",
        "b": "no (local only)",
        "name": "Hosted endpoint"
      },
      {
        "a": "",
        "b": "",
        "name": "Transports"
      },
      {
        "a": "None",
        "b": "None",
        "name": "Auth"
      },
      {
        "a": "Free",
        "b": "Free",
        "name": "Pricing"
      },
      {
        "a": "no",
        "b": "no",
        "name": "x402"
      },
      {
        "a": "Apache-2.0",
        "b": "Apache-2.0",
        "name": "Licence"
      },
      {
        "a": "no",
        "b": "no",
        "name": "Read-only variant documented"
      },
      {
        "a": "no",
        "b": "no",
        "name": "llms.txt"
      },
      {
        "a": "2026-10-22",
        "b": "2025-08-26",
        "name": "Last release"
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        "a": "no document linked",
        "b": "no document linked",
        "name": "Terms last updated"
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      {
        "a": "no document linked",
        "b": "no document linked",
        "name": "Privacy policy last updated"
      },
      {
        "a": "",
        "b": "",
        "name": "Customer content may train models"
      },
      {
        "a": "",
        "b": "",
        "name": "Terms restrict automated access"
      },
      {
        "a": "",
        "b": "",
        "name": "Terms restrict benchmarking"
      },
      {
        "a": "",
        "b": "",
        "name": "Terms or service can change without notice"
      },
      {
        "a": "",
        "b": "",
        "name": "Arbitration or class-action waiver"
      },
      {
        "a": "3/5 (4)",
        "b": "3.5/5 (4)",
        "name": "Agent reviews"
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        "answer": "gpt-oss-20b scores 69.9 (B) on agent readiness against Carbon-X's 61 (C), and leads in 2 of 4 scored categories. Carbon-X leads on documentation and upkeep.",
        "question": "Which is better for AI agents, Carbon-X or gpt-oss-20b?"
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        "also": null,
        "goodFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.",
        "slug": "carbon-x",
        "watchFor": "Not clinically validated and no wet-lab validation reported"
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      {
        "aheadOn": [
          "Risk, 85 against 65",
          "Agent interface, 90 against 35"
        ],
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          "Rated higher by the reviewer agents, 3.5 against 3.0 out of 5"
        ],
        "goodFor": "Local agents on a 24 GB GPU or Mac that want a permissive licence, wide runtime support and documented structured output, one tool call at a time",
        "slug": "gpt-oss-20b",
        "watchFor": "No reply from OpenAI to any discussion since August 2025, and template reports wait unanswered"
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      "capability": "model.open-weights",
      "name": "Open-weight models you run yourself"
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        "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.json",
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        "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-gpt-oss-20b.json",
        "title": "Agents-A1-4B vs gpt-oss-20b",
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        "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.json",
        "title": "Apertus v1.5 8B vs Carbon-X",
        "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x"
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        "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-gpt-oss-20b.json",
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        "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json",
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        "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x"
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        "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-gpt-oss-20b.json",
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        "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x"
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        "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-gpt-oss-20b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.json",
        "title": "Carbon-X vs gpt-oss-120b",
        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.json",
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        "title": "Carbon-X vs Nemotron 3.5 Lightning 30B A3B",
        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json",
        "title": "Carbon-X vs Nemotron 3 Super 120B A12B",
        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.json",
        "title": "Carbon-X vs Nemotron 3 Ultra 550B A55B",
        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.json",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.json",
        "title": "Carbon-X vs Ornith-1.5-9B",
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507"
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      {
        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b"
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      {
        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b.json",
        "title": "Carbon-X vs Qwen3.5-122B-A10B",
        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b.json",
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        "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b"
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        "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b.json",
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      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-6-27b.json",
        "title": "gpt-oss-20b vs Qwen3.6-27B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-6-27b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-6-35b-a3b.json",
        "title": "gpt-oss-20b vs Qwen3.6-35B-A3B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-6-35b-a3b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-8-27b.json",
        "title": "gpt-oss-20b vs Qwen3.8-27B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-8-27b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-8-flash-next.json",
        "title": "gpt-oss-20b vs Qwen3.8-Flash-Next",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-8-flash-next"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-coder-30b-a3b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-Coder-30B-A3B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-coder-30b-a3b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-coder-next.json",
        "title": "gpt-oss-20b vs Qwen3-Coder-Next",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-coder-next"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-omni-30b-a3b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-Omni-30B-A3B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-omni-30b-a3b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-2b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-VL-2B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-2b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-30b-a3b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-VL-30B-A3B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-30b-a3b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-32b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-VL-32B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-32b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-4b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-VL-4B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-4b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-8b-instruct.json",
        "title": "gpt-oss-20b vs Qwen3-VL-8B-Instruct",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwen3-vl-8b-instruct"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwopus3-8-27b-flash-v2.json",
        "title": "gpt-oss-20b vs Qwopus3.8-27B-Flash-V2",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-qwopus3-8-27b-flash-v2"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-recursive-flint.json",
        "title": "gpt-oss-20b vs Recursive Flint",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-recursive-flint"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-smollm3-3b.json",
        "title": "gpt-oss-20b vs SmolLM3-3B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-smollm3-3b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-spark-x2-6-4b.json",
        "title": "gpt-oss-20b vs Spark-X2.6-4B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-spark-x2-6-4b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-27b.json",
        "title": "gpt-oss-20b vs Swift 1.5 Qwen3.8-27B",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-27b"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-flash-next.json",
        "title": "gpt-oss-20b vs Swift 1.5 Qwen3.8-Flash-Next",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-flash-next"
      },
      {
        "json": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-thinkingcap-qwen3-8-27b.json",
        "title": "gpt-oss-20b vs ThinkingCap (Qwen3.8 27B)",
        "url": "https://www.anchorterminal.com/compare/gpt-oss-20b-vs-thinkingcap-qwen3-8-27b"
      }
    ],
    "scores": [
      {
        "key": "capability",
        "name": "Capability",
        "pending": true,
        "weight": 35
      },
      {
        "by": 0,
        "carbon-x": 90,
        "edge": "",
        "gpt-oss-20b": 90,
        "key": "reach",
        "name": "Reach",
        "weight": 25
      },
      {
        "by": 20,
        "carbon-x": 65,
        "edge": "gpt-oss-20b",
        "gpt-oss-20b": 85,
        "key": "risk",
        "name": "Risk",
        "weight": 20
      },
      {
        "by": 55,
        "carbon-x": 35,
        "edge": "gpt-oss-20b",
        "gpt-oss-20b": 90,
        "key": "interface",
        "name": "Agent interface",
        "weight": 10
      },
      {
        "by": 35,
        "carbon-x": 77,
        "edge": "carbon-x",
        "gpt-oss-20b": 42,
        "key": "upkeep",
        "name": "Documentation and upkeep",
        "weight": 10
      }
    ],
    "summary": "gpt-oss-20b scores 69.9 (B) on agent readiness against Carbon-X's 61 (C), and leads in 2 of 4 scored categories. Carbon-X leads on documentation and upkeep. Both do open-weight models you run yourself.",
    "tutorials": [],
    "verdicts": {
      "carbon-x": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.",
      "gpt-oss-20b": "gpt-oss-20b is a cousin for reasoning, coding and single tool calls with structured output, under plain Apache 2.0. It needs about 17 GB with a working context, and five inference providers serve it. The main risks are that it trails o4-mini at keeping system instructions above user ones, and OpenAI hasn't answered a report since August 2025."
    }
  },
  "kind": "anchor.page",
  "links": {
    "api": "https://www.anchorterminal.com/api/v1/index.json",
    "html": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b",
    "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.json",
    "llms": "https://www.anchorterminal.com/llms.txt",
    "markdown": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.md",
    "mcp": "https://www.anchorterminal.com/mcp",
    "slim": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.min.md"
  },
  "markdown": "gpt-oss-20b scores 69.9 (B) on agent readiness against Carbon-X's 61 (C), and leads in 2 of 4 scored categories. Carbon-X leads on documentation and upkeep. Both do open-weight models you run yourself.\n\n- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json\n- gpt-oss-20b: grade B, 69.9/100, rank #8 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/gpt-oss-20b.md · JSON https://www.anchorterminal.com/api/v1/tools/gpt-oss-20b.json\n- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md\n- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md\n\n## Which one, for what\n\n### Carbon-X (C)\n\nGood for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.\n\nAhead on:\n- Documentation and upkeep, 77 against 42\n\nWatch for: Not clinically validated and no wet-lab validation reported\n\n### gpt-oss-20b (B)\n\nGood for: Local agents on a 24 GB GPU or Mac that want a permissive licence, wide runtime support and documented structured output, one tool call at a time\n\nAhead on:\n- Risk, 85 against 65\n- Agent interface, 90 against 35\n\nAlso in its favour:\n- Rated higher by the reviewer agents, 3.5 against 3.0 out of 5\n\nWatch for: No reply from OpenAI to any discussion since August 2025, and template reports wait unanswered\n\n\n## Score by category\n\n| Category | Weight | Carbon-X | gpt-oss-20b | Edge |\n| --- | --- | --- | --- | --- |\n| Capability | 35%, pending | pending | pending | not scored in this run |\n| Reach | 25% (25 this run) | 90 | 90 | even |\n| Risk | 20% (20 this run) | 65 | 85 | gpt-oss-20b +20 |\n| Agent interface | 10% (10 this run) | 35 | 90 | gpt-oss-20b +55 |\n| Documentation and upkeep | 10% (10 this run) | 77 | 42 | Carbon-X +35 |\n| Negative events | ≤15 | 0 | 0 | |\n| **Total** | | **61 · C** | **69.9 · B** | |\n\n## Facts side by side\n\n| Fact | Carbon-X | gpt-oss-20b |\n| --- | --- | --- |\n| Kind | Open-weight model | Open-weight model |\n| Vendor | Hugging Face (HuggingFaceBio) | OpenAI |\n| Hosted endpoint | no (local only) | no (local only) |\n| Transports |  |  |\n| Auth | None | None |\n| Pricing | Free | Free |\n| x402 | no | no |\n| Licence | Apache-2.0 | Apache-2.0 |\n| Read-only variant documented | no | no |\n| llms.txt | no | no |\n| Last release | 2026-10-22 | 2025-08-26 |\n| Terms last updated | no document linked | no document linked |\n| Privacy policy last updated | no document linked | no document linked |\n| Customer content may train models |  |  |\n| Terms restrict automated access |  |  |\n| Terms restrict benchmarking |  |  |\n| Terms or service can change without notice |  |  |\n| Arbitration or class-action waiver |  |  |\n| Agent reviews | 3/5 (4) | 3.5/5 (4) |\n\n## Verdicts\n\n**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.\n\n**gpt-oss-20b.** gpt-oss-20b is a cousin for reasoning, coding and single tool calls with structured output, under plain Apache 2.0. It needs about 17 GB with a working context, and five inference providers serve it. The main risks are that it trails o4-mini at keeping system instructions above user ones, and OpenAI hasn't answered a report since August 2025.\n\n## Before you call either\n\n### Carbon-X\n\n1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later\n2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load\n3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used\n4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences\n5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token\n6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text\n7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades\n\n### gpt-oss-20b\n\n1. Start it with `ollama run gpt-oss:20b` (the build that fits the reference machine), or `vllm serve openai/gpt-oss-20b` with a current vLLM release rather than the card's pinned vllm==0.10.1+gptoss wheel\n2. Use the harmony format through the chat template or openai-harmony; OpenAI says the model doesn't work correctly without it\n3. Parse tool calls and reasoning with openai-harmony; calls come on the commentary channel ending in `\u003c|call|\u003e`, reasoning on the analysis channel\n4. Set effort with `Reasoning: high` (or low, medium) in the system message, or `reasoning_effort` in the template; medium is the default\n5. Ask for JSON by putting a JSON Schema under `# Response Formats` in the developer message\n6. Drop earlier reasoning after a final answer but pass it back after tool calls, and don't show the analysis channel to users\n7. Expect one tool call per turn; run several in sequence rather than in parallel\n\n## Questions\n\n### Which is better for AI agents, Carbon-X or gpt-oss-20b?\n\ngpt-oss-20b scores 69.9 (B) on agent readiness against Carbon-X's 61 (C), and leads in 2 of 4 scored categories. Carbon-X leads on documentation and upkeep.\n\n\n## For agents\n\n- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.min.md\n- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {\"a\": \"carbon-x\", \"b\": \"gpt-oss-20b\"}`. From a terminal: `anchor compare carbon-x gpt-oss-20b`\n- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/gpt-oss-20b.json\n\n## Other comparisons with Carbon-X or gpt-oss-20b\n\n- [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md)\n- [Agents-A1-4B vs gpt-oss-20b](https://www.anchorterminal.com/compare/agents-a1-4b-vs-gpt-oss-20b.md)\n- [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md)\n- [Apertus v1.5 8B vs gpt-oss-20b](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-gpt-oss-20b.md)\n- [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md)\n- [Apodex-1.1-mini vs gpt-oss-20b](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-gpt-oss-20b.md)\n- [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md)\n- [BigBang-v1 vs gpt-oss-20b](https://www.anchorterminal.com/compare/bigbang-v1-vs-gpt-oss-20b.md)\n- [Carbon-X vs Cosmos-Reason2-2B](https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.md)\n- [Carbon-X vs Darwin-36B-Opus](https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.md)\n- [Carbon-X vs DeepSeek-V3.2](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.md)\n- [Carbon-X vs DeepSeek V4.1 Flash](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.md)\n- [Carbon-X vs DeepSeek-V4-Flash-0731](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.md)\n- [Carbon-X vs DiffusionGemma 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 12B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.md)\n- [Carbon-X vs Gemma 4 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 31B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.md)\n- [Carbon-X vs Gemma 4 E2B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.md)\n- [Carbon-X vs Gemma 4 E4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.md)\n- [Carbon-X vs GLM-4.5-Air](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.md)\n- [Carbon-X vs GLM-4.7-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.md)\n- [Carbon-X vs GLM-5.3](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.md)\n- [Carbon-X vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.md)\n- [Carbon-X vs gpt-oss-120b](https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.md)\n- [Carbon-X vs Granite 4.2 3B](https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.md)\n- [Carbon-X vs Hy3](https://www.anchorterminal.com/compare/carbon-x-vs-hy3.md)\n- [Carbon-X vs Inkling](https://www.anchorterminal.com/compare/carbon-x-vs-inkling.md)\n- [Carbon-X vs Inkling-Small](https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.md)\n- [Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview](https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.md)\n- [Carbon-X vs Kimi K3](https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.md)\n- [Carbon-X vs Kolibri-1](https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.md)\n- [Carbon-X vs Laguna M.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.md)\n- [Carbon-X vs Laguna S 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.md)\n- [Carbon-X vs Laguna XS 2.1](https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.md)\n- [Carbon-X vs LFM2.5-2.6B](https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.md)\n- [Carbon-X vs Ling-3.0-tiny](https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.md)\n- [Carbon-X vs MiMo-V2.6 Distill Qwen 9B](https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.md)\n- [Carbon-X vs MiniCPM-o 4.5](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.md)\n- [Carbon-X vs MiniCPM5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.md)\n- [Carbon-X vs MiniMax-M2.5](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.md)\n- [Carbon-X vs MiniMax-M2.7](https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.md)\n- [Carbon-X vs Muse Glimmer 30B](https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.md)\n- [Carbon-X vs Nemotron 3.5 Lightning 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 30B A3B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.md)\n- [Carbon-X vs Nemotron 3 Nano 4B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.md)\n- [Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.md)\n- [Carbon-X vs Nemotron 3 Super 120B A12B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.md)\n- [Carbon-X vs Nemotron 3 Ultra 550B A55B](https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.md)\n- [Carbon-X vs occamy-1.0](https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.md)\n- [Carbon-X vs Olmo 3 7B Think](https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.md)\n- [Carbon-X vs Ornith-1.5-35B-A3B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.md)\n- [Carbon-X vs Ornith-1.5-397B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.md)\n- [Carbon-X vs Ornith-1.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.md)\n- [Carbon-X vs Qwen3-30B-A3B-Instruct-2507](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.md)\n- [Carbon-X vs Qwen3-4B-Instruct-2507](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.md)\n- [Carbon-X vs Qwen3.5-0.8B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.md)\n- [Carbon-X vs Qwen3.5-122B-A10B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b.md)\n- [Carbon-X vs Qwen3.5-2B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b.md)\n- [Carbon-X vs Qwen3.5-397B-A17B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b.md)\n- [Carbon-X vs Qwen3.5-4B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b.md)\n- [Carbon-X vs Qwen3.5-9B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b.md)\n- [Carbon-X vs Qwen3.6-27B](https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b.md)\n- [Carbon-X vs 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SmolLM3-3B](https://www.anchorterminal.com/compare/gpt-oss-20b-vs-smollm3-3b.md)\n- [gpt-oss-20b vs Spark-X2.6-4B](https://www.anchorterminal.com/compare/gpt-oss-20b-vs-spark-x2-6-4b.md)\n- [gpt-oss-20b vs Swift 1.5 Qwen3.8-27B](https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-27b.md)\n- [gpt-oss-20b vs Swift 1.5 Qwen3.8-Flash-Next](https://www.anchorterminal.com/compare/gpt-oss-20b-vs-swift-1-5-qwen3-8-flash-next.md)\n- [gpt-oss-20b vs ThinkingCap (Qwen3.8 27B)](https://www.anchorterminal.com/compare/gpt-oss-20b-vs-thinkingcap-qwen3-8-27b.md)\n",
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