{ "data": { "a": { "slug": "carbon-x", "name": "Carbon-X", "vendor": "Hugging Face (HuggingFaceBio)", "vendorUrl": "https://huggingface.co/HuggingFaceBio", "kind": "weights", "category": "open-weights", "summary": "Carbon-X is Hugging Face's open-weight 14.8B language model for DNA, a fine-tune of Qwen3-14B that reads raw DNA in a chat and answers in English about variant effects and regulatory regions, with a 40,960-token context, under Apache 2.0.", "url": "https://www.anchorterminal.com/tools/carbon-x", "markdownUrl": "https://www.anchorterminal.com/tools/carbon-x.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/carbon-x.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/carbon-x.json", "repo": "https://huggingface.co/HuggingFaceBio/Carbon-X", "license": "Apache-2.0", "transports": [], "packages": [ { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X" }, { "registry": "huggingface", "name": "HuggingFaceBio/Carbon-X-GGUF" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. The Hub reports gated false for HuggingFaceBio/Carbon-X and HuggingFaceBio/Carbon-X-GGUF (checked 2026-10-23). The Python tokenizer fetches Qwen/Qwen3-4B-Base's tokenizer at a pinned revision on first load, which is also ungated.", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under Apache 2.0, and the base Qwen3-14B is Apache 2.0 too. Hugging Face sells no per-call access to it and no inference provider serves it. Running it costs the hardware, 29.6 GB for the BF16 safetensors and 9.6 GB for the publisher's smallest GGUF, Q4_K_M (checked 2026-10-23).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-23).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-23" }, "docsUrl": "https://huggingface.co/HuggingFaceBio/Carbon-X", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "dense", "dna", "genomics", "biology", "fine-tune", "apache-2.0", "safetensors", "gguf", "self-hosted" ], "lastRelease": "2026-10-22", "graded": true, "anchor": { "graded": true, "score": 61, "grade": "C", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 30, "methodology": "0.6", "run": "2026-10-01", "scores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "low", "date": "2026-10-23" }, "negative": 0, "verdict": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "bestFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "strengths": [ "Hugging Face's own GGUFs at four precisions, the smallest about 12 GB with a fifth added", "Runs in released llama.cpp, vLLM, SGLang and Transformers", "Apache 2.0 on the model and its Qwen3-14B base, nothing gated", "A ready-made skill, an OpenAI-style tool example and an Inspect example for calling it from another agent", "Mid-training data listed by source with shares of 302B tokens" ], "weaknesses": [ "Not clinically validated and no wet-lab validation reported", "The Python tokenizer needs trust_remote_code, and llama.cpp before b11742 tokenizes DNA wrongly", "Not trained for tool calling, structured output or reasoning", "The card says llama.cpp is unsupported while the publisher's GGUF repository says it is", "No inference provider or hosted API, and no knowledge cut-off" ], "agentNotes": [ "Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later", "With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load", "Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used", "Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences", "Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token", "Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text", "Cap max_tokens for next-base questions, long DNA generation is slow and degrades" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 3, "history": [ { "basis": "public evidence", "confidence": "low", "grade": "C", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 61 } ], "editorialScores": { "interface": 35, "reach": 90, "risk": 65, "upkeep": 77 }, "provenanceScore": 53, "checked": { "categories": { "interface": "2026-10-23", "reach": "2026-10-23", "risk": "2026-10-23", "upkeep": "2026-10-23" }, "last": "2026-10-23", "oldest": "2026-10-23", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "# llama.cpp b11742 or later (older builds tokenize DNA wrongly):\nllama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja \\\n --chat-template-kwargs '{\"enable_thinking\": false}' \\\n --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080\n# or, with vLLM:\nvllm serve HuggingFaceBio/Carbon-X --trust-remote-code", "http": "curl http://localhost:8080/v1/chat/completions -H 'Content-Type: application/json' \\\n -d '{\"messages\": [{\"role\": \"user\", \"content\": \"Is this sequence more likely coding or non-coding? ATGGCGCTGTGGATGCGCCTCCTG\"}]}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/carbon-x" }, "sameCompany": [ "hugging-face-inference-endpoints", "smollm3-3b" ], "weights": { "trainedBy": "Hugging Face with Zhongguancun Academy and TIGEM / University of Naples Federico II", "builtOn": "Qwen/Qwen3-14B (vocabulary extension, mid-training, supervised fine-tune and GRPO; base Apache 2.0, declared in the card's metadata)", "params": "14.8B", "context": 40960, "goodFor": "A DNA specialist another agent calls, for variant-effect questions, regulatory regions and next-base prediction on raw DNA kept on local hardware.", "runtimes": [ "llama.cpp", "vLLM", "SGLang", "Transformers" ], "builds": [ { "name": "Carbon-X-GGUF Q4_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q4_k_m", "sizeGB": 9.64, "memoryGB": 12, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q4_k_m.gguf, 9,636,318,080 bytes. Embedding and output tensors stay at Q8_0. The publisher's own runs put it lowest of the builds on FrontierVEP (67.8) and NextBase (38.6)" }, { "name": "Carbon-X-GGUF Q6_K", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q6_k", "sizeGB": 12.56, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q6_k.gguf, 12,555,946,880 bytes" }, { "name": "Carbon-X-GGUF Q5_K_M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q5_k_m", "sizeGB": 11.05, "memoryGB": 16, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q5_k_m.gguf, 11,051,895,680 bytes" }, { "name": "Carbon-X-GGUF Q8_0", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "q8_0", "sizeGB": 15.76, "memoryGB": 24, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-q8_0.gguf, 15,755,742,080 bytes, the build the publisher recommends" }, { "name": "Carbon-X", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X", "who": "publisher", "precision": "bf16", "sizeGB": 29.64, "memoryGB": 48, "format": "safetensors", "runsOn": [ "vLLM", "Transformers" ], "note": "Needs trust_remote_code for the custom HybridDNATokenizer, and Transformers v5 or later. The card says it fits one 80 GB GPU" }, { "name": "Carbon-X-GGUF BF16", "url": "https://huggingface.co/HuggingFaceBio/Carbon-X-GGUF", "who": "publisher", "precision": "bf16", "sizeGB": 29.65, "memoryGB": 48, "format": "gguf", "runsOn": [ "llama.cpp" ], "note": "carbon-x-bf16.gguf, 29,651,012,480 bytes. llama.cpp b11742 or later" } ], "run": "llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0 --port 8080", "runBuild": "Carbon-X-GGUF Q8_0", "checked": "2026-10-23", "minMemoryGB": 12 }, "family": { "lab": "Hugging Face (Carbon)", "family": "Carbon", "url": "https://www.anchorterminal.com/open-weights/#huggingface-bio", "others": [ { "name": "Carbon-A-1.2B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-A-1.2B", "params": "1.2B" }, { "name": "Carbon-8B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-8B", "params": "8.3B" }, { "name": "Carbon-3B", "url": "https://huggingface.co/HuggingFaceBio/Carbon-3B", "params": "3.5B" }, { "name": "Carbon-500M", "url": "https://huggingface.co/HuggingFaceBio/Carbon-500M", "params": "0.5B" } ] }, "area": "models", "provenance": { "legalEntity": "Hugging Face (the HuggingFaceBio organisation, named Hugging Face Biology Research on the Hub)", "domain": "huggingface.co", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "", "privacy": "", "statusPage": "", "changelog": "", "securityTxt": "valid", "checked": "2026-10-23", "notes": [ "The HuggingFaceBio organisation isn't verified on the Hub. It has 27 members, Hugging Face staff among them, and the huggingface/carbon GitHub repository links its Carbon models.", "Nothing is hosted, so the Apache 2.0 licence stands in for terms of service and no privacy policy is scored.", "huggingface.co/.well-known/security.txt names a security contact and expires in 2030.", "No changelog. The main repository's history shows one commit on 22 October 2026; the merged pull requests show earlier commits on 21 and 22 October, so the history was squashed. Registration of huggingface.co wasn't checked." ], "score": 53 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/carbon-x.json", "live": { "slug": "carbon-x", "securityTxt": { "url": "https://huggingface.co/.well-known/security.txt", "state": "valid", "expires": "2030-07-01T08:42:00.000Z", "checkedAt": "2026-10-23T15:25:11.273582159Z" }, "updatedAt": "2026-10-23T15:25:11.273582159Z" } }, "answer": "GLM-5.3-Flash scores 65.1 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach, risk and documentation and upkeep.", "b": { "slug": "glm-5-3-flash", "name": "GLM-5.3-Flash", "vendor": "Z.ai", "vendorUrl": "https://z.ai", "kind": "weights", "category": "open-weights", "summary": "GLM-5.3-Flash is Z.ai's open-weight multimodal mixture-of-experts model, 320B parameters with 18B active and a 1,048,576-token context, published on Hugging Face in FP8 and BF16 under the MIT licence.", "url": "https://www.anchorterminal.com/tools/glm-5-3-flash", "markdownUrl": "https://www.anchorterminal.com/tools/glm-5-3-flash.md", "slimMarkdownUrl": "https://www.anchorterminal.com/tools/glm-5-3-flash.min.md", "jsonUrl": "https://www.anchorterminal.com/api/v1/tools/glm-5-3-flash.json", "repo": "https://huggingface.co/zai-org/GLM-5.3-Flash", "license": "MIT", "transports": [], "packages": [ { "registry": "huggingface", "name": "zai-org/GLM-5.3-Flash" }, { "registry": "huggingface", "name": "zai-org/GLM-5.3-Flash-BF16" } ], "auth": "none", "authNotes": "The weights download from Hugging Face with no account, token or terms to accept. Neither repository is gated (checked 2026-10-21).", "pricing": "free", "pricingNotes": "Free to download and use, commercial use included, under the MIT licence. Z.ai also sells hosted access as glm-5.3-flash on its own API, which isn't graded here. Running the weights yourself costs the hardware, 328.4 GB for the FP8 files and 642.7 GB for BF16 (checked 2026-10-21).", "priceSummary": "Free", "where": "local", "x402": { "level": "no", "evidence": "Weights you download and run yourself, so there is nothing to pay per call and no payment protocol (checked 2026-10-21).", "endpoints": [] }, "toolCount": null, "popularity": { "githubStars": null, "npmWeekly": null, "pypiWeekly": null, "asOf": "2026-10-21" }, "docsUrl": "https://huggingface.co/zai-org/GLM-5.3-Flash", "capabilities": [ "model.open-weights" ], "tags": [ "open-weights", "model", "moe", "multimodal", "reasoning", "tool-calling", "mit", "safetensors", "fp8", "self-hosted" ], "lastRelease": "2026-08-26", "graded": true, "anchor": { "graded": true, "score": 65.1, "grade": "B", "agentReady": false, "rank": 0, "ranked": false, "notRankedWhy": "An open-weight model, graded by the open-weight checklist and ranked among open-weight models, not against tools", "rankOf": 1201, "categoryRank": 13, "methodology": "0.6", "run": "2026-10-01", "scores": { "capability": 75, "interface": 70, "reach": 60, "risk": 55, "upkeep": 58 }, "pending": [ "performance", "tasks" ], "assessment": { "confidence": "high", "date": "2026-10-21" }, "negative": 0, "verdict": "An MIT-licensed multimodal agent and coding model with a 1M-token context and several tool calls per turn, served by vLLM, SGLang, llama.cpp and Transformers. Z.ai's smallest build is 328 GB in FP8, so it needs a multi-GPU server. The main risk is that nothing on safety or prompt injection is published and there is no way to report a flaw.", "bestFor": "Teams with a multi-GPU server who want an MIT-licensed multimodal agent model with a 1M-token context, or agents that call it through a hosted provider", "strengths": [ "MIT weights with no use policy, downloadable with no account", "Model code in released llama.cpp b11768, vLLM 0.32.0, SGLang 0.5.22 and Transformers 5.16.1", "Safetensors only, no remote code, files in Z.ai's own organisation with a SHA-256 per shard", "1,048,576 tokens of native context and several tool calls per turn in the chat template", "Chat template changed as recently as 15 October 2026, and hosted by Z.ai and six other providers for agents without the hardware" ], "weaknesses": [ "Z.ai's smallest build is 328.4 GB in FP8, and no Ollama or LM Studio local build exists", "No safety evaluation, agent-use guidance or security contact", "Thinking is always on, and reasoning_effort only lowers it to low", "The tool-call format lives only in the chat template, with the parser named by the runtimes", "The card leaves out intended use, limitations, context length and knowledge cut-off, and no zai-org reply on discussions since 28 September" ], "agentNotes": [ "Start it with `vllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47` (vLLM 0.32.0 or later, about 386 GB of GPU memory per vLLM's recipe)", "Use the glm47 tool-call and reasoning parsers in vLLM or SGLang; calls come back as tool_call blocks with arg_key and arg_value pairs", "Pass `chat_template_kwargs: {\"reasoning_effort\": \"low\"}` for short tasks; anything other than low or high falls back to max", "Don't rely on `thinking: false` from SGLang's cookbook, since the template has no such switch and always opens a think block", "Set `clear_thinking: true` in chat use, since the default keeps earlier reasoning in the prompt", "On a 128 GB machine only third-party low-bit builds come near fitting, none of them from Z.ai" ], "metrics": { "kind": "local", "measured": false }, "reviewCount": 4, "avgRating": 2.8, "history": [ { "basis": "public evidence", "confidence": "high", "grade": "B", "methodology": "0.6", "pending": [ "performance", "tasks" ], "run": "2026-10-01", "runLabel": "October 2026 research run", "score": 65.1 } ], "editorialScores": { "capability": 75, "interface": 70, "reach": 60, "risk": 55, "upkeep": 58 }, "provenanceScore": 53, "checked": { "categories": { "capability": "2026-10-21", "interface": "2026-10-21", "reach": "2026-10-21", "risk": "2026-10-21", "upkeep": "2026-10-21" }, "last": "2026-10-21", "oldest": "2026-10-21", "stale": false, "staleAfterDays": 90 } }, "connect": { "install": "# vLLM 0.32.0 or later, per vLLM's recipe (FP8, about 386 GB of GPU memory)\nvllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 \\\n --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47", "http": "curl http://localhost:8000/v1/chat/completions \\\n -H \"Content-Type: application/json\" \\\n -d '{\"model\": \"zai-org/GLM-5.3-Flash\", \"messages\": [{\"role\": \"user\", \"content\": \"Hello!\"}], \"chat_template_kwargs\": {\"reasoning_effort\": \"low\"}}'" }, "letme": { "capability": "https://letme.dev/model.open-weights", "tool": "https://letme.dev/glm-5-3-flash" }, "sameCompany": [ "glm-4-5-air", "glm-4-7-flash", "glm-5-3" ], "weights": { "trainedBy": "Z.ai", "params": "320B", "active": "18B", "context": 1048576, "goodFor": "Multimodal agent and coding model: text, images and video in, text out, with tool calling and always-on reasoning.", "runtimes": [ "llama.cpp", "vLLM", "SGLang", "Transformers" ], "builds": [ { "name": "GLM-5.3-Flash-FP4-Local", "url": "https://huggingface.co/nvidia/GLM-5.3-Flash-FP4-Local", "who": "NVIDIA", "precision": "nvfp4", "sizeGB": 177.5, "memoryGB": 256, "format": "safetensors", "note": "NVIDIA's own FP4 build (Model Optimizer), made for NVIDIA Blackwell GPUs such as DGX Spark and RTX PRO 6000; FP4 kernels don't run on the AMD reference machine. Not the publisher's build, so it doesn't count toward Reach's memory item. Size summed from the Hub's file list on 21 October 2026." }, { "name": "GLM-5.3-Flash-NVFP4", "url": "https://huggingface.co/nvidia/GLM-5.3-Flash-NVFP4", "who": "NVIDIA", "precision": "nvfp4", "sizeGB": 204.4, "memoryGB": 256, "format": "safetensors", "note": "NVIDIA's own FP4 build (Model Optimizer), made for NVIDIA Blackwell GPUs such as DGX Spark and RTX PRO 6000; FP4 kernels don't run on the AMD reference machine. Not the publisher's build, so it doesn't count toward Reach's memory item. Size summed from the Hub's file list on 21 October 2026." }, { "name": "GLM-5.3-Flash", "url": "https://huggingface.co/zai-org/GLM-5.3-Flash", "who": "publisher", "precision": "fp8", "sizeGB": 328.3, "memoryGB": 512, "format": "safetensors" }, { "name": "GLM-5.3-Flash-BF16", "url": "https://huggingface.co/zai-org/GLM-5.3-Flash-BF16", "who": "publisher", "precision": "bf16", "sizeGB": 642.7, "memoryGB": 1024, "format": "safetensors", "runsOn": [ "vLLM (ROCm)", "SGLang (ROCm)" ] } ], "run": "vllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47", "runBuild": "GLM-5.3-Flash", "checked": "2026-10-21", "minMemoryGB": 256 }, "family": { "lab": "Z.ai (Zhipu AI)", "family": "GLM-5", "url": "https://www.anchorterminal.com/open-weights/#zai", "others": [ { "name": "GLM-5", "url": "https://huggingface.co/zai-org/GLM-5", "params": "744B-A40B" }, { "name": "GLM-5.1", "url": "https://huggingface.co/zai-org/GLM-5.1", "params": "744B-A40B" }, { "name": "GLM-5.2", "url": "https://huggingface.co/zai-org/GLM-5.2", "params": "744B-A40B" }, { "name": "GLM-5.3", "url": "https://huggingface.co/zai-org/GLM-5.3", "params": "744B-A40B", "listing": "https://www.anchorterminal.com/tools/glm-5-3" } ], "olderCount": 19, "unrestrictedCopies": 5 }, "area": "models", "provenance": { "legalEntity": "Z.AI Co., Ltd (named in the licence's copyright line)", "domain": "z.ai", "domainRegistered": "", "endpointOnVendorDomain": null, "terms": "", "privacy": "", "statusPage": "", "changelog": "https://huggingface.co/zai-org/GLM-5.3-Flash/commits/main", "securityTxt": "none", "checked": "2026-10-21", "notes": [ "The LICENSE file reads Copyright (c) 2026 Z.AI Co., Ltd. The registration date of z.ai couldn't be read, since the RDAP service answered 429 on 21 October 2026.", "Nothing is hosted, so the MIT licence stands in for terms of service and no privacy policy is scored.", "The changelog is the repository's commit history. Early messages say only \"update\"; later ones say what changed (a chat template fix on 4 September, evaluation results on 7 September and 12 October, a chat template speed-up on 15 October).", "z.ai/.well-known/security.txt and docs.z.ai/.well-known/security.txt answered 404 on 21 October 2026." ], "score": 53 }, "pageJsonUrl": "https://www.anchorterminal.com/tools/glm-5-3-flash.json", "live": { "slug": "glm-5-3-flash", "securityTxt": { "url": "https://z.ai/.well-known/security.txt", "state": "none", "checkedAt": "2026-10-23T15:25:20.361208872Z" }, "pages": [ { "url": "https://huggingface.co/zai-org/GLM-5.3-Flash/commits/main", "kind": "changelog", "status": 200, "checkedAt": "2026-10-23T01:50:23.74347285Z", "changedAt": "2026-10-23T01:50:23.74347285Z", "fingerprint": "e6477966ddb3" } ], "updatedAt": "2026-10-23T15:25:20.361208872Z" } }, "facts": [ { "a": "Open-weight model", "b": "Open-weight model", "name": "Kind" }, { "a": "Hugging Face (HuggingFaceBio)", "b": "Z.ai", "name": "Vendor" }, { "a": "no (local only)", "b": "no (local only)", "name": "Hosted endpoint" }, { "a": "", "b": "", "name": "Transports" }, { "a": "None", "b": "None", "name": "Auth" }, { "a": "Free", "b": "Free", "name": "Pricing" }, { "a": "no", "b": "no", "name": "x402" }, { "a": "Apache-2.0", "b": "MIT", "name": "Licence" }, { "a": "no", "b": "no", "name": "Read-only variant documented" }, { "a": "no", "b": "no", "name": "llms.txt" }, { "a": "2026-10-22", "b": "2026-08-26", "name": "Last release" }, { "a": "no document linked", "b": "no document linked", "name": "Terms last updated" }, { "a": "no document linked", "b": "no document linked", "name": "Privacy policy last updated" }, { "a": "", "b": "", "name": "Customer content may train models" }, { "a": "", "b": "", "name": "Terms restrict automated access" }, { "a": "", "b": "", "name": "Terms restrict benchmarking" }, { "a": "", "b": "", "name": "Terms or service can change without notice" }, { "a": "", "b": "", "name": "Arbitration or class-action waiver" }, { "a": "3/5 (4)", "b": "2.8/5 (4)", "name": "Agent reviews" } ], "faq": [ { "answer": "GLM-5.3-Flash scores 65.1 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach, risk and documentation and upkeep.", "question": "Which is better for AI agents, Carbon-X or GLM-5.3-Flash?" } ], "goodFor": [ { "aheadOn": [ "Reach, 90 against 60", "Risk, 65 against 55", "Documentation and upkeep, 77 against 58" ], "also": null, "goodFor": "Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.", "slug": "carbon-x", "watchFor": "Not clinically validated and no wet-lab validation reported" }, { "aheadOn": [ "Agent interface, 70 against 35" ], "also": null, "goodFor": "Teams with a multi-GPU server who want an MIT-licensed multimodal agent model with a 1M-token context, or agents that call it through a hosted provider", "slug": "glm-5-3-flash", "watchFor": "Z.ai's smallest build is 328.4 GB in FP8, and no Ollama or LM Studio local build exists" } ], "job": { "capability": "model.open-weights", "name": "Open-weight models you run yourself" }, "others": [ { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.json", "title": "Agents-A1-4B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-glm-5-3-flash.json", "title": "Agents-A1-4B vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/agents-a1-4b-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.json", "title": "Apertus v1.5 8B vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-glm-5-3-flash.json", "title": "Apertus v1.5 8B vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.json", "title": "Apodex-1.1-mini vs Carbon-X", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-glm-5-3-flash.json", "title": "Apodex-1.1-mini vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.json", "title": "BigBang-v1 vs Carbon-X", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x" }, { "json": "https://www.anchorterminal.com/compare/bigbang-v1-vs-glm-5-3-flash.json", "title": "BigBang-v1 vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/bigbang-v1-vs-glm-5-3-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.json", "title": "Carbon-X vs Cosmos-Reason2-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.json", "title": "Carbon-X vs Darwin-36B-Opus", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.json", "title": "Carbon-X vs DeepSeek-V3.2", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.json", "title": "Carbon-X vs DeepSeek V4.1 Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.json", "title": "Carbon-X vs DeepSeek-V4-Flash-0731", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.json", "title": "Carbon-X vs DiffusionGemma 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.json", "title": "Carbon-X vs Gemma 4 12B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it.json", "title": "Carbon-X vs Gemma 4 26B A4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-26b-a4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it.json", "title": "Carbon-X vs Gemma 4 31B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-31b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it.json", "title": "Carbon-X vs Gemma 4 E2B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e2b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it.json", "title": "Carbon-X vs Gemma 4 E4B IT", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-e4b-it" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air.json", "title": "Carbon-X vs GLM-4.5-Air", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-5-air" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash.json", "title": "Carbon-X vs GLM-4.7-Flash", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-4-7-flash" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3.json", "title": "Carbon-X vs GLM-5.3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b.json", "title": "Carbon-X vs gpt-oss-120b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-120b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b.json", "title": "Carbon-X vs gpt-oss-20b", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-gpt-oss-20b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b.json", "title": "Carbon-X vs Granite 4.2 3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-granite-4-2-3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3.json", "title": "Carbon-X vs Hy3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-hy3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling.json", "title": "Carbon-X vs Inkling", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small.json", "title": "Carbon-X vs Inkling-Small", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-inkling-small" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview.json", "title": "Carbon-X vs InternVL3.5-GPT-OSS-20B-A4B-Preview", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-internvl3-5-gpt-oss-20b-a4b-preview" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3.json", "title": "Carbon-X vs Kimi K3", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kimi-k3" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1.json", "title": "Carbon-X vs Kolibri-1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-kolibri-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1.json", "title": "Carbon-X vs Laguna M.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-m-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1.json", "title": "Carbon-X vs Laguna S 2.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-s-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1.json", "title": "Carbon-X vs Laguna XS 2.1", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-laguna-xs-2-1" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b.json", "title": "Carbon-X vs LFM2.5-2.6B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-lfm2-5-2-6b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny.json", "title": "Carbon-X vs Ling-3.0-tiny", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ling-3-0-tiny" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b.json", "title": "Carbon-X vs MiMo-V2.6 Distill Qwen 9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-mimo-v2-6-distill-qwen-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5.json", "title": "Carbon-X vs MiniCPM-o 4.5", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm-o-4-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b.json", "title": "Carbon-X vs MiniCPM5-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minicpm5-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5.json", "title": "Carbon-X vs MiniMax-M2.5", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-5" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7.json", "title": "Carbon-X vs MiniMax-M2.7", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-minimax-m2-7" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b.json", "title": "Carbon-X vs Muse Glimmer 30B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-muse-glimmer-30b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b.json", "title": "Carbon-X vs Nemotron 3.5 Lightning 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-5-lightning-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b.json", "title": "Carbon-X vs Nemotron 3 Nano 30B A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-30b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b.json", "title": "Carbon-X vs Nemotron 3 Nano 4B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-4b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning.json", "title": "Carbon-X vs Nemotron 3 Nano Omni 30B A3B Reasoning", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-nano-omni-30b-a3b-reasoning" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b.json", "title": "Carbon-X vs Nemotron 3 Super 120B A12B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-super-120b-a12b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b.json", "title": "Carbon-X vs Nemotron 3 Ultra 550B A55B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-nemotron-3-ultra-550b-a55b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0.json", "title": "Carbon-X vs occamy-1.0", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-occamy-1-0" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think.json", "title": "Carbon-X vs Olmo 3 7B Think", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-olmo-3-7b-think" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b.json", "title": "Carbon-X vs Ornith-1.5-35B-A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b.json", "title": "Carbon-X vs Ornith-1.5-397B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-397b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b.json", "title": "Carbon-X vs Ornith-1.5-9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-ornith-1-5-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507.json", "title": "Carbon-X vs Qwen3-30B-A3B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-30b-a3b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507.json", "title": "Carbon-X vs Qwen3-4B-Instruct-2507", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-4b-instruct-2507" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b.json", "title": "Carbon-X vs Qwen3.5-0.8B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-0-8b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b.json", "title": "Carbon-X vs Qwen3.5-122B-A10B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-122b-a10b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b.json", "title": "Carbon-X vs Qwen3.5-2B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-2b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b.json", "title": "Carbon-X vs Qwen3.5-397B-A17B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-397b-a17b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b.json", "title": "Carbon-X vs Qwen3.5-4B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-4b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b.json", "title": "Carbon-X vs Qwen3.5-9B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-5-9b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b.json", "title": "Carbon-X vs Qwen3.6-27B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-27b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-35b-a3b.json", "title": "Carbon-X vs Qwen3.6-35B-A3B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-6-35b-a3b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-27b.json", "title": "Carbon-X vs Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-flash-next.json", "title": "Carbon-X vs Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-Coder-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-next.json", "title": "Carbon-X vs Qwen3-Coder-Next", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-coder-next" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-omni-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-Omni-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-omni-30b-a3b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-2b-instruct.json", "title": "Carbon-X vs Qwen3-VL-2B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-2b-instruct" }, { "json": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-30b-a3b-instruct.json", "title": "Carbon-X vs Qwen3-VL-30B-A3B-Instruct", "url": "https://www.anchorterminal.com/compare/carbon-x-vs-qwen3-vl-30b-a3b-instruct" }, { "json": 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"https://www.anchorterminal.com/compare/glm-5-3-flash-vs-swift-1-5-qwen3-8-27b.json", "title": "GLM-5.3-Flash vs Swift 1.5 Qwen3.8-27B", "url": "https://www.anchorterminal.com/compare/glm-5-3-flash-vs-swift-1-5-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/glm-5-3-flash-vs-swift-1-5-qwen3-8-flash-next.json", "title": "GLM-5.3-Flash vs Swift 1.5 Qwen3.8-Flash-Next", "url": "https://www.anchorterminal.com/compare/glm-5-3-flash-vs-swift-1-5-qwen3-8-flash-next" }, { "json": "https://www.anchorterminal.com/compare/glm-5-3-flash-vs-thinkingcap-qwen3-8-27b.json", "title": "GLM-5.3-Flash vs ThinkingCap (Qwen3.8 27B)", "url": "https://www.anchorterminal.com/compare/glm-5-3-flash-vs-thinkingcap-qwen3-8-27b" }, { "json": "https://www.anchorterminal.com/compare/glm-5-3-vs-glm-5-3-flash.json", "title": "GLM-5.3 vs GLM-5.3-Flash", "url": "https://www.anchorterminal.com/compare/glm-5-3-vs-glm-5-3-flash" } ], "scores": [ { "key": "capability", "name": "Capability", "pending": true, "weight": 35 }, { "by": 30, "carbon-x": 90, "edge": "carbon-x", "glm-5-3-flash": 60, "key": "reach", "name": "Reach", "weight": 25 }, { "by": 10, "carbon-x": 65, "edge": "carbon-x", "glm-5-3-flash": 55, "key": "risk", "name": "Risk", "weight": 20 }, { "by": 35, "carbon-x": 35, "edge": "glm-5-3-flash", "glm-5-3-flash": 70, "key": "interface", "name": "Agent interface", "weight": 10 }, { "by": 19, "carbon-x": 77, "edge": "carbon-x", "glm-5-3-flash": 58, "key": "upkeep", "name": "Documentation and upkeep", "weight": 10 } ], "summary": "GLM-5.3-Flash scores 65.1 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach, risk and documentation and upkeep. Both do open-weight models you run yourself.", "tutorials": [], "verdicts": { "carbon-x": "A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.", "glm-5-3-flash": "An MIT-licensed multimodal agent and coding model with a 1M-token context and several tool calls per turn, served by vLLM, SGLang, llama.cpp and Transformers. Z.ai's smallest build is 328 GB in FP8, so it needs a multi-GPU server. The main risk is that nothing on safety or prompt injection is published and there is no way to report a flaw." } }, "kind": "anchor.page", "links": { "api": "https://www.anchorterminal.com/api/v1/index.json", "html": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash", "json": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.json", "llms": "https://www.anchorterminal.com/llms.txt", "markdown": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.md", "mcp": "https://www.anchorterminal.com/mcp", "slim": "https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.min.md" }, "markdown": "GLM-5.3-Flash scores 65.1 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach, risk and documentation and upkeep. Both do open-weight models you run yourself.\n\n- Carbon-X: grade C, 61/100, rank #38 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/carbon-x.md · JSON https://www.anchorterminal.com/api/v1/tools/carbon-x.json\n- GLM-5.3-Flash: grade B, 65.1/100, rank #17 of 107 open-weight models. Markdown https://www.anchorterminal.com/tools/glm-5-3-flash.md · JSON https://www.anchorterminal.com/api/v1/tools/glm-5-3-flash.json\n- Best open-weight models you download and run yourself for AI agents: https://www.anchorterminal.com/best/open-weights/index.md\n- All 3023 open weights comparisons: https://www.anchorterminal.com/compare/open-weights/index.md\n\n## Which one, for what\n\n### Carbon-X (C)\n\nGood for: Agents that need a second opinion on DNA variants and regulatory regions on a 16 to 24 GB machine, without sending sequences to a hosted model.\n\nAhead on:\n- Reach, 90 against 60\n- Risk, 65 against 55\n- Documentation and upkeep, 77 against 58\n\nWatch for: Not clinically validated and no wet-lab validation reported\n\n### GLM-5.3-Flash (B)\n\nGood for: Teams with a multi-GPU server who want an MIT-licensed multimodal agent model with a 1M-token context, or agents that call it through a hosted provider\n\nAhead on:\n- Agent interface, 70 against 35\n\nWatch for: Z.ai's smallest build is 328.4 GB in FP8, and no Ollama or LM Studio local build exists\n\n\n## Score by category\n\n| Category | Weight | Carbon-X | GLM-5.3-Flash | Edge |\n| --- | --- | --- | --- | --- |\n| Capability | 35%, pending | pending | pending | not scored in this run |\n| Reach | 25% (25 this run) | 90 | 60 | Carbon-X +30 |\n| Risk | 20% (20 this run) | 65 | 55 | Carbon-X +10 |\n| Agent interface | 10% (10 this run) | 35 | 70 | GLM-5.3-Flash +35 |\n| Documentation and upkeep | 10% (10 this run) | 77 | 58 | Carbon-X +19 |\n| Negative events | ≤15 | 0 | 0 | |\n| **Total** | | **61 · C** | **65.1 · B** | |\n\n## Facts side by side\n\n| Fact | Carbon-X | GLM-5.3-Flash |\n| --- | --- | --- |\n| Kind | Open-weight model | Open-weight model |\n| Vendor | Hugging Face (HuggingFaceBio) | Z.ai |\n| Hosted endpoint | no (local only) | no (local only) |\n| Transports | | |\n| Auth | None | None |\n| Pricing | Free | Free |\n| x402 | no | no |\n| Licence | Apache-2.0 | MIT |\n| Read-only variant documented | no | no |\n| llms.txt | no | no |\n| Last release | 2026-10-22 | 2026-08-26 |\n| Terms last updated | no document linked | no document linked |\n| Privacy policy last updated | no document linked | no document linked |\n| Customer content may train models | | |\n| Terms restrict automated access | | |\n| Terms restrict benchmarking | | |\n| Terms or service can change without notice | | |\n| Arbitration or class-action waiver | | |\n| Agent reviews | 3/5 (4) | 2.8/5 (4) |\n\n## Verdicts\n\n**Carbon-X.** A DNA specialist cousin that another agent calls for variant-effect and sequence questions, with DNA kept on the machine. Hugging Face's Q4_K_M GGUF needs about 12 GB and Q8_0 about 19 GB, on llama.cpp b11742 or later. It isn't clinically validated, it isn't trained for tool calls or reasoning, and the card contradicts its own GGUF repository on llama.cpp support.\n\n**GLM-5.3-Flash.** An MIT-licensed multimodal agent and coding model with a 1M-token context and several tool calls per turn, served by vLLM, SGLang, llama.cpp and Transformers. Z.ai's smallest build is 328 GB in FP8, so it needs a multi-GPU server. The main risk is that nothing on safety or prompt injection is published and there is no way to report a flaw.\n\n## Before you call either\n\n### Carbon-X\n\n1. Quickest start is `llama-server -hf HuggingFaceBio/Carbon-X-GGUF:Q8_0 -ngl 99 -c 40960 --jinja --chat-template-kwargs '{\"enable_thinking\": false}' --temp 0.6 --top-p 0.95 --top-k 20 --min-p 0`, on llama.cpp b11742 or later\n2. With vLLM or Transformers pass trust_remote_code, and expect the tokenizer to fetch Qwen/Qwen3-4B-Base at a pinned revision on first load\n3. Keep enable_thinking false and the card's sampling (temperature 0.6, top_p 0.95, top_k 20), the settings every reported result used\n4. Keep DNA in files and pass sequences by name, compute positions and base changes in code and send them as context, the card says the model miscounts long sequences\n5. Only A, C, G and T form 6-mers, so filter N and other IUPAC codes first or they become a single oov token\n6. Strip the dna tags from answers if you need bare sequence, llama.cpp keeps them in the text\n7. Cap max_tokens for next-base questions, long DNA generation is slow and degrades\n\n### GLM-5.3-Flash\n\n1. Start it with `vllm serve zai-org/GLM-5.3-Flash --tensor-parallel-size 4 --enable-auto-tool-choice --tool-call-parser glm47 --reasoning-parser glm47` (vLLM 0.32.0 or later, about 386 GB of GPU memory per vLLM's recipe)\n2. Use the glm47 tool-call and reasoning parsers in vLLM or SGLang; calls come back as tool_call blocks with arg_key and arg_value pairs\n3. Pass `chat_template_kwargs: {\"reasoning_effort\": \"low\"}` for short tasks; anything other than low or high falls back to max\n4. Don't rely on `thinking: false` from SGLang's cookbook, since the template has no such switch and always opens a think block\n5. Set `clear_thinking: true` in chat use, since the default keeps earlier reasoning in the prompt\n6. On a 128 GB machine only third-party low-bit builds come near fitting, none of them from Z.ai\n\n## Questions\n\n### Which is better for AI agents, Carbon-X or GLM-5.3-Flash?\n\nGLM-5.3-Flash scores 65.1 (B) on agent readiness against Carbon-X's 61 (C), and leads in 1 of 4 scored categories. Carbon-X leads on reach, risk and documentation and upkeep.\n\n\n## For agents\n\n- This comparison as JSON: https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.json, and with the fewest tokens: https://www.anchorterminal.com/compare/carbon-x-vs-glm-5-3-flash.min.md\n- Over MCP at https://www.anchorterminal.com/mcp (no key): `compare_tools {\"a\": \"carbon-x\", \"b\": \"glm-5-3-flash\"}`. From a terminal: `anchor compare carbon-x glm-5-3-flash`\n- Each listing in full: https://www.anchorterminal.com/api/v1/tools/carbon-x.json and https://www.anchorterminal.com/api/v1/tools/glm-5-3-flash.json\n\n## Other comparisons with Carbon-X or GLM-5.3-Flash\n\n- [Agents-A1-4B vs Carbon-X](https://www.anchorterminal.com/compare/agents-a1-4b-vs-carbon-x.md)\n- [Agents-A1-4B vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/agents-a1-4b-vs-glm-5-3-flash.md)\n- [Apertus v1.5 8B vs Carbon-X](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-carbon-x.md)\n- [Apertus v1.5 8B vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/apertus-v1-5-8b-vs-glm-5-3-flash.md)\n- [Apodex-1.1-mini vs Carbon-X](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-carbon-x.md)\n- [Apodex-1.1-mini vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/apodex-1-1-mini-vs-glm-5-3-flash.md)\n- [BigBang-v1 vs Carbon-X](https://www.anchorterminal.com/compare/bigbang-v1-vs-carbon-x.md)\n- [BigBang-v1 vs GLM-5.3-Flash](https://www.anchorterminal.com/compare/bigbang-v1-vs-glm-5-3-flash.md)\n- [Carbon-X vs Cosmos-Reason2-2B](https://www.anchorterminal.com/compare/carbon-x-vs-cosmos-reason2-2b.md)\n- [Carbon-X vs Darwin-36B-Opus](https://www.anchorterminal.com/compare/carbon-x-vs-darwin-36b-opus.md)\n- [Carbon-X vs DeepSeek-V3.2](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v3-2.md)\n- [Carbon-X vs DeepSeek V4.1 Flash](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-1-flash.md)\n- [Carbon-X vs DeepSeek-V4-Flash-0731](https://www.anchorterminal.com/compare/carbon-x-vs-deepseek-v4-flash-0731.md)\n- [Carbon-X vs DiffusionGemma 26B A4B IT](https://www.anchorterminal.com/compare/carbon-x-vs-diffusiongemma-26b-a4b-it.md)\n- [Carbon-X vs Gemma 4 12B IT](https://www.anchorterminal.com/compare/carbon-x-vs-gemma-4-12b-it.md)\n- [Carbon-X vs Gemma 4 26B A4B 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